Gene description for MAPK8
Gene name mitogen-activated protein kinase 8
Gene symbol MAPK8
Other names/aliases JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
Species Homo sapiens
 Experiment description of studies that identified MAPK8 in Plasma

1
Experiment ID2130
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched)
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyMass spectometry
Luciferase assay
ELISA
EV-TRACK -

2
Experiment ID2131
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched)
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyMass spectometry
Luciferase assay
ELISA
EV-TRACK -

3
Experiment ID2132
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched) - responders
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyELISA
EV-TRACK -

4
Experiment ID2133
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched) - responders
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyELISA
EV-TRACK -

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