Gene description for PSMC5
Gene name proteasome 26S subunit, ATPase 5
Gene symbol PSMC5
Other names/aliases RPT6
S8
SUG-1
SUG1
TBP10
TRIP1
p45
p45/SUG
Species Homo sapiens
 Experiment description of studies that identified PSMC5 in Retinal pigment epithelial cells

1
Experiment ID1256
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24400796   
OrganismHomo sapiens
Experiment descriptionExosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.
AuthorsKang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H.
Journal name J Proteome Res.
Publication year2014
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140174: EV-METRIC:13%, 13%

2
Experiment ID2699
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

3
Experiment ID2700
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

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