Gene description for RNF213
Gene name	ring finger protein 213
Gene symbol	RNF213
Other names/aliases	ALO17 C17orf27 KIAA1618 MYMY2 MYSTR NET57
Species	Homo sapiens
Experiment description of studies that identified RNF213 in Urine
1 Experiment ID 63 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 19056867    Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting EV-TRACK -
2 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120168: EV-METRIC:14%
3 Experiment ID 540 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23886663    Organism Homo sapiens Experiment description LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Authors Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, Standaert DG, Kojima K, Mobley JA, West AB. Journal name Hum Mol Genet Publication year 2013 Sample Urine Sample name Normal-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130075: EV-METRIC:11%, 11%, 33%
4 Experiment ID 1027 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24211404    Organism Homo sapiens Experiment description Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. Authors Zubiri I, Posada-Ayala M, Sanz-Maroto A, Calvo E, Martin-Lorenzo M, Gonzalez-Calero L, de la Cuesta F, Lopez JA, Fernandez-Fernandez B, Ortiz A, Vivanco F, Alvarez-Llamas G. Journal name J Proteomics. Publication year 2014 Sample Urine Sample name Urine - Diabetic nephropathy (DN) patients Isolation/purification methods Ultracentrifugation ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140245: EV-METRIC:22%, 25%, 22%