Gene description for ACTB
Gene name	actin beta
Gene symbol	ACTB
Other names/aliases	BKRNS BNS BRWS1 CSMH DDS1 PS1TP5BP1 THC8
Species	Homo sapiens
Experiment description of studies that identified ACTB in Platelets
1 Experiment ID 369 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 16212402    Organism Homo sapiens Experiment description The platelet microparticle proteome. Authors Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. Journal name J Proteome Res Publication year 2005 Sample Platelets Sample name Normal donors-Platelets Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
2 Experiment ID 406 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 19806257    Organism Homo sapiens Experiment description Proteomic and functional characterisation of platelet microparticle size classes. Authors Dean WL, Lee MJ, Cummins TD, Schultz DJ, Powell DW. Journal name Thromb Haemost Publication year 2009 Sample Platelets Sample name Normal donors-Platelets Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 1344 Identified molecule protein Extracellular vesicle type Platelet-derived microparticles MISEV EV-like nanoparticles Identification method Western blotting PubMed ID 33009394    Organism Homo sapiens Experiment description Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Authors Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. Journal name Nat Commun Publication year 2020 Sample Platelets Sample name Platelets derived from umbilical cord blood Isolation/purification methods Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Flow cytometry Western blotting qPCR EV-TRACK -
4 Experiment ID 2529 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Western blotting PubMed ID 34293122    Organism Homo sapiens Experiment description Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Authors Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Journal name Blood Publication year 2021 Sample Platelets Sample name Platelets (thrombin-activated) - healthy volunteers Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting Immuno-EM Flow cytometry EV-TRACK -