 Gene description for HCN2 |
| Gene name |
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 |
| Gene symbol |
HCN2 |
| Other names/aliases |
BCNG-2
BCNG2
EIG17
FEB2
GEFSP11
HAC-1 |
| Species |
Homo sapiens |
| Experiment description of studies that identified HCN2 in Glioblastoma cells |
| 1
|
| Experiment ID | 203 |
| Identified molecule | mrna
|
| Extracellular vesicle type | Microvesicles |
| MISEV | EVs |
| Identification method | Microarray
|
| PubMed ID |
19011622 
|
| Organism | Homo sapiens |
| Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
| Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
| Journal name |
Nat Cell Biol
|
| Publication year | 2008 |
| Sample | Glioblastoma cells |
| Sample name | Glioblastoma cells |
| Isolation/purification methods | Differential centrifugation
Ultracentrifugation
Filtration |
| Flotation density | - |
| Molecules identified in the study | Protein
miRNA
mRNA |
| Methods used in the study | RT-PCR
Antibody array
Microarray |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 494 |
| Identified molecule | mRNA
|
| Extracellular vesicle type | Microvesicles |
| MISEV | EVs |
| Identification method | Microarray
|
| PubMed ID |
23344721
|
| Organism | Homo sapiens |
| Experiment description | miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. |
| Authors | Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O. |
| Journal name |
Mol Ther Nucleic Acids
|
| Publication year | 2012 |
| Sample | Glioblastoma cells |
| Sample name | Primary glioblastoma multiforme cells (11/5) |
| Isolation/purification methods | - |
| Flotation density | - |
| Molecules identified in the study | mRNA |
| Methods used in the study | Microarray |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 495 |
| Identified molecule | mRNA
|
| Extracellular vesicle type | Microvesicles |
| MISEV | EVs |
| Identification method | Microarray
|
| PubMed ID |
23344721
|
| Organism | Homo sapiens |
| Experiment description | miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. |
| Authors | Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O. |
| Journal name |
Mol Ther Nucleic Acids
|
| Publication year | 2012 |
| Sample | Glioblastoma cells |
| Sample name | Primary glioblastoma multiforme cells (20/3) |
| Isolation/purification methods | - |
| Flotation density | - |
| Molecules identified in the study | mRNA |
| Methods used in the study | Microarray |
| EV-TRACK |
-
|
|
|
