Gene description for C4A
Gene name	complement C4A (Rodgers blood group)
Gene symbol	C4A
Other names/aliases	C4 C4A2 C4A3 C4A4 C4A6 C4AD C4S CO4 CPAMD2 RG
Species	Homo sapiens
Experiment description of studies that identified C4A in Urine
1 Experiment ID 478 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of bladder cancer-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%
2 Experiment ID 479 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of hernia-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%
3 Experiment ID 507 Identified molecule protein Extracellular vesicle type Exosomes/Nanovesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23511837    Organism Homo sapiens Experiment description Differential protein profiling of renal cell carcinoma urinary exosomes. Authors Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. Journal name Mol Biosyst Publication year 2013 Sample Urine Sample name Normal-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130016: EV-METRIC:44%
4 Experiment ID 508 Identified molecule protein Extracellular vesicle type Exosomes/Nanovesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23511837    Organism Homo sapiens Experiment description Differential protein profiling of renal cell carcinoma urinary exosomes. Authors Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. Journal name Mol Biosyst Publication year 2013 Sample Urine Sample name Renal cell carcinoma patient-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130016: EV-METRIC:44%
5 Experiment ID 512 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23533145    Organism Homo sapiens Experiment description In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Authors Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. Journal name Proteomics Publication year 2013 Sample Urine Sample name Low-grade prostate cancer patient-Expressed prostatic secretions in urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130224: EV-METRIC:14%
6 Experiment ID 513 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23533145    Organism Homo sapiens Experiment description In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Authors Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. Journal name Proteomics Publication year 2013 Sample Urine Sample name Normal-Expressed prostatic secretions in urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130224: EV-METRIC:14%
7 Experiment ID 725 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25471207    Organism Homo sapiens Experiment description Intraluminal proteome and peptidome of human urinary extracellular vesicles. Authors Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. Journal name Proteomics Clin Appl. Publication year 2015 Sample Urine Sample name Normal crude urine- Trypsinized Isolation/purification methods Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140189: EV-METRIC:25%
8 Experiment ID 1027 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24211404    Organism Homo sapiens Experiment description Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. Authors Zubiri I, Posada-Ayala M, Sanz-Maroto A, Calvo E, Martin-Lorenzo M, Gonzalez-Calero L, de la Cuesta F, Lopez JA, Fernandez-Fernandez B, Ortiz A, Vivanco F, Alvarez-Llamas G. Journal name J Proteomics. Publication year 2014 Sample Urine Sample name Urine - Diabetic nephropathy (DN) patients Isolation/purification methods Ultracentrifugation ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140245: EV-METRIC:22%, 25%, 22%