Gene description for DEFA1B
Gene name	defensin alpha 1B
Gene symbol	DEFA1B
Other names/aliases	HNP-1 HP-1 HP1
Species	Homo sapiens
Experiment description of studies that identified DEFA1B in Breast milk
1 Experiment ID 652 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28290293    Organism Homo sapiens Experiment description Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Authors Yng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X. Journal name Food Res Int Publication year 2017 Sample Breast milk Sample name Colostrum Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.7 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
2 Experiment ID 653 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28290293    Organism Homo sapiens Experiment description Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Authors Yng M, Song D, Cao X, Wu R, Liu B, Ye W, Wu J, Yue X. Journal name Food Res Int Publication year 2017 Sample Breast milk Sample name Mature milk Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.7 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 951 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
4 Experiment ID 955 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D6 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV160000: EV-METRIC:50%
5 Experiment ID 956 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D7 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV160000: EV-METRIC:50%