Gene description for Mlkl
Gene name mixed lineage kinase domain-like
Gene symbol Mlkl
Other names/aliases 9130019I15Rik
Species Mus musculus
 Experiment description of studies that identified Mlkl in Plasma

1
Experiment ID1871
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36063142   
OrganismMus musculus
Experiment descriptionNecroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL
AuthorsGupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B.
Journal name J Extracell Vesicles
Publication year2022
SamplePlasma
Sample namePlasma from Ripk3-/- mice
Isolation/purification methodsDifferential centrifugation
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID1872
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36063142   
OrganismMus musculus
Experiment descriptionNecroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL
AuthorsGupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B.
Journal name J Extracell Vesicles
Publication year2022
SamplePlasma
Sample namePlasma from Ripk3+/+ mice
Isolation/purification methodsDifferential centrifugation
ExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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