Gene description for CA9
Gene name	carbonic anhydrase 9
Gene symbol	CA9
Other names/aliases	CAIX MN
Species	Homo sapiens
Experiment description of studies that identified CA9 in Glioblastoma cells
1 Experiment ID 203 Identified molecule mrna Extracellular vesicle type Microvesicles MISEV EVs Identification method Microarray PubMed ID 19011622    Organism Homo sapiens Experiment description Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Authors Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO Journal name Nat Cell Biol Publication year 2008 Sample Glioblastoma cells Sample name Glioblastoma cells Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA mRNA Methods used in the study RT-PCR Antibody array Microarray EV-TRACK -
2 Experiment ID 494 Identified molecule mRNA Extracellular vesicle type Microvesicles MISEV EVs Identification method Microarray PubMed ID 23344721    Organism Homo sapiens Experiment description miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Authors Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O. Journal name Mol Ther Nucleic Acids Publication year 2012 Sample Glioblastoma cells Sample name Primary glioblastoma multiforme cells (11/5) Isolation/purification methods - Flotation density - Molecules identified in the study mRNA Methods used in the study Microarray EV-TRACK -
3 Experiment ID 495 Identified molecule mRNA Extracellular vesicle type Microvesicles MISEV EVs Identification method Microarray PubMed ID 23344721    Organism Homo sapiens Experiment description miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Authors Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O. Journal name Mol Ther Nucleic Acids Publication year 2012 Sample Glioblastoma cells Sample name Primary glioblastoma multiforme cells (20/3) Isolation/purification methods - Flotation density - Molecules identified in the study mRNA Methods used in the study Microarray EV-TRACK -
4 Experiment ID 1242 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25261722    Organism Homo sapiens Experiment description Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Authors Kore RA, Abraham EC. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Glioblastoma cells Sample name U373 cells treated with 10ng/ml of IL-1. Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140183: EV-METRIC:22%