Gene description for RAP2B
Gene name	RAP2B, member of RAS oncogene family
Gene symbol	RAP2B
Other names/aliases	-
Species	Bos taurus
Experiment description of studies that identified RAP2B in Bovine milk
1 Experiment ID 439 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 22129587    Organism Bos taurus Experiment description Bovine milk exosome proteome. Authors Reinhardt TA, Lippolis JD, Nonnecke BJ, Sacco RE. Journal name J Proteomics Publication year 2012 Sample Bovine milk Sample name Normal cow-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120041: EV-METRIC:56%
2 Experiment ID 503 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23459212    Organism Bos taurus Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD. Journal name J Proteomics Publication year 2013 Sample Bovine milk Sample name Staphylococcus aureus-infected-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130111: EV-METRIC:43%
3 Experiment ID 1045 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 12 h and 24 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1046 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 72 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
5 Experiment ID 1047 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 48 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
6 Experiment ID 1048 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - mature milk Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
7 Experiment ID 2815 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Western blotting Mass spectrometry Small RNA sequencing EV-TRACK -
8 Experiment ID 2822 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Mass spectrometry Small RNA sequencing EV-TRACK -