Gene description for ACTN4
Gene name	actinin alpha 4
Gene symbol	ACTN4
Other names/aliases	ACTININ-4 FSGS FSGS1
Species	Homo sapiens
Experiment description of studies that identified ACTN4 in Liver cancer cells
1 Experiment ID 1551 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 10K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 1552 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 1553 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 10K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
4 Experiment ID 1554 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 32082513    Organism Homo sapiens Experiment description Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Authors Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G. Journal name J Extracell Vesicles Publication year 2020 Sample Liver cancer cells Sample name Huh-7 - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 2476 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -
6 Experiment ID 2477 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34401050    Organism Homo sapiens Experiment description TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Authors Liu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP. Journal name J Extracell Vesicles Publication year 2021 Sample Liver cancer cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immuno-EM Mass spectrometry EV-TRACK -