Gene description for H4C4
Gene name	H4 clustered histone 4
Gene symbol	H4C4
Other names/aliases	H4-16 H4/b H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C5 H4C6 H4C8 H4C9 H4FB HIST1H4D dJ221C16.9
Species	Homo sapiens
Experiment description of studies that identified H4C4 in Bladder cancer cells
1 Experiment ID 76 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 20224111    Organism Homo sapiens Experiment description Proteomics analysis of bladder cancer exosomes. Authors Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. Journal name MCP Publication year 2010 Sample Bladder cancer cells Sample name HT1376 Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.10-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Western blotting FACS EV-TRACK EV100014: EV-METRIC:38%, 14%, 44%
2 Experiment ID 905 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
3 Experiment ID 930 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%