Gene description for H4C2
Gene name	H4 clustered histone 2
Gene symbol	H4C2
Other names/aliases	H4-16 H4/I H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4FI HIST1H4B
Species	Homo sapiens
Experiment description of studies that identified H4C2 in Endothelial cells
1 Experiment ID 385 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
2 Experiment ID 386 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by PAI-1-Endothelial cell (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 387 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by TNF-alpha-Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 502 Identified molecule protein Extracellular vesicle type Membrane vesicles/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23436686    Organism Homo sapiens Experiment description A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Authors Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. Journal name Proteomics Publication year 2013 Sample Endothelial cells Sample name Serum-starved-Human umbilical vascular endothelial cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130048: EV-METRIC:44%
5 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%