Gene description for TNFSF10
Gene name	TNF superfamily member 10
Gene symbol	TNFSF10
Other names/aliases	APO2L Apo-2L CD253 TANCR TL2 TNLG6A TRAIL
Species	Homo sapiens
Experiment description of studies that identified TNFSF10 in Colorectal cancer cells
1 Experiment ID 22 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting Immunoelectron Microscopy PubMed ID 15940614    Organism Homo sapiens Experiment description Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Authors Huber V, Fais S, Iero M, Lugini L, Canese P, Squarcina P, Zaccheddu A, Colone M, Arancia G, Gentile M, Seregni E, Valenti R, Ballabio G, Belli F, Leo E, Parmiani G, Rivoltini L. Journal name GASTRO Publication year 2005 Sample Colorectal cancer cells Sample name SW403 1869col CRC28462 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Immunoelectron microscopy FACS EV-TRACK -
2 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles MISEV EVs Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina] EV-TRACK -