Gene description for TNFSF10
Gene name	TNF superfamily member 10
Gene symbol	TNFSF10
Other names/aliases	APO2L Apo-2L CD253 TANCR TL2 TNLG6A TRAIL
Species	Homo sapiens
Experiment description of studies that identified TNFSF10 in T cells
1 Experiment ID 292 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting FACS PubMed ID 10415024    Organism Homo sapiens Experiment description Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles Authors Martíz-Lorenzo MJ, Anel A, Gamen S, Monle n I, Lasierra P, Larrad L, Piño A, Alava MA, Naval J Journal name J Immunol Publication year 1999 Sample T cells Sample name Jurkat - PHA stimulated Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK -
2 Experiment ID 293 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting FACS PubMed ID 10415024    Organism Homo sapiens Experiment description Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles Authors Martíz-Lorenzo MJ, Anel A, Gamen S, Monle n I, Lasierra P, Larrad L, Piño A, Alava MA, Naval J Journal name J Immunol Publication year 1999 Sample T cells Sample name T cell blasts Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting FACS EV-TRACK -
3 Experiment ID 1005 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts - exosomes pulldown with EWI-2 as a bait Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130110: EV-METRIC:22%