Gene description for HGS |
Gene name |
hepatocyte growth factor-regulated tyrosine kinase substrate |
Gene symbol |
HGS |
Other names/aliases |
HRS |
Species |
Homo sapiens |
Experiment description of studies that identified HGS in Plasma |
1
|
Experiment ID | 354 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry [Orbitrap Velos]
|
PubMed ID |
24115447
|
Organism | Homo sapiens |
Experiment description | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma |
Authors | Mathivanan,S. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Plasma |
Sample name | Plasma - Normal |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap Velos] Western blotting |
EV-TRACK |
EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%
|
|
|
2
|
Experiment ID | 2991 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Healthy donors |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting ELISA |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 2992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Melanoma stage IV patients |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting ELISA |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 2995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Melanoma stage IV patients - Fraction 7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | 1.44 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 2996 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Melanoma stage IV patients - Fraction 8 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | 1.56 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 2997 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Melanoma stage IV patients - Fraction 9 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | 1.178 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 2998 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Homo sapiens |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Melanoma stage IV patients - Fraction 10 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | 1.193 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|