Gene description for ITGBL1
Gene name integrin subunit beta like 1
Gene symbol ITGBL1
Other names/aliases OSCP
TIED
Species Homo sapiens
 Experiment description of studies that identified ITGBL1 in Plasma

1
Experiment ID3307
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
ELISA
PubMed ID 32139701   
OrganismHomo sapiens
Experiment descriptionPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
AuthorsJi Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameHealthy volunteers
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

2
Experiment ID3308
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
ELISA
PubMed ID 32139701   
OrganismHomo sapiens
Experiment descriptionPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
AuthorsJi Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameNon-metastatic colorectal cancer patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

3
Experiment ID3309
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32139701   
OrganismHomo sapiens
Experiment descriptionPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
AuthorsJi Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameMetastatic colorectal cancer patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID3310
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 32139701   
OrganismHomo sapiens
Experiment descriptionPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
AuthorsJi Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameColorectal cancer patients with lung metastasis
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyELISA
EV-TRACK -

5
Experiment ID3311
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 32139701   
OrganismHomo sapiens
Experiment descriptionPrimary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
AuthorsJi Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameColorectal cancer patients with liver metastasis
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyELISA
EV-TRACK -

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