Gene description for CD63
Gene name CD63 molecule
Gene symbol CD63
Other names/aliases AD1
HOP-26
ME491
MLA1
OMA81H
Pltgp40
TSPAN30
Species Homo sapiens
 Experiment description of studies that identified CD63 in Serum

1
Experiment ID1031
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (ExoRNeasy)
Isolation/purification methodsexoEasy columns
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

2
Experiment ID1032
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (ExoRNeasy)
Isolation/purification methodsexoEasy columns
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

3
Experiment ID1033
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (qEV)
Isolation/purification methodsqEV size-exclusion column
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

4
Experiment ID1034
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (qEV)
Isolation/purification methodsqEV size-exclusion column
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

5
Experiment ID1035
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (Exo-spin)
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

6
Experiment ID1036
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (Exo-spin)
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -

7
Experiment ID1509
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 3
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID1510
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 4
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID1511
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 5
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID1512
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 6
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID2881
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 30918259   
OrganismHomo sapiens
Experiment descriptionSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
AuthorsIm EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC.
Journal name Nat Commun
Publication year2019
SampleSerum
Sample nameBALB/c implanted with MDA-MB-231-luci (+)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID2882
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 30918259   
OrganismHomo sapiens
Experiment descriptionSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
AuthorsIm EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC.
Journal name Nat Commun
Publication year2019
SampleSerum
Sample nameBALB/c implanted with MDA-MB-231-luci (+)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID2883
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 30918259   
OrganismHomo sapiens
Experiment descriptionSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
AuthorsIm EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC.
Journal name Nat Commun
Publication year2019
SampleSerum
Sample nameBALB/c implanted with MDA-MB-231-luci (+)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

14
Experiment ID2884
Identified moleculeprotein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 30918259   
OrganismHomo sapiens
Experiment descriptionSulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
AuthorsIm EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC.
Journal name Nat Commun
Publication year2019
SampleSerum
Sample nameBALB/c implanted with MDA-MB-231-luci (+)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID3068
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample nameHealthy controls
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

16
Experiment ID3069
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 33827783   
OrganismHomo sapiens
Experiment descriptionExosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment
AuthorsXie Z, Gao Y, Ho C, Li L, Jin C, Wang X, Zou C, Mao Y, Wang X, Li Q, Fu D, Zhang YF.
Journal name Gut
Publication year2022
SampleSerum
Sample namePancreatic ductal adenocarcinoma patients
Isolation/purification methodsTotal Exosome isolation Kit
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

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