Gene description for CD81
Gene name CD81 molecule
Gene symbol CD81
Other names/aliases CVID6
S5.7
TAPA1
TSPAN28
Species Homo sapiens
 Experiment description of studies that identified CD81 in Faeces

1
Experiment ID1325
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33431899   
OrganismHomo sapiens
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameHealthy volunteers
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
HPLC
EV-TRACK -

2
Experiment ID1326
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33431899   
OrganismHomo sapiens
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameType 2 diabetes patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
HPLC
EV-TRACK -

3
Experiment ID2355
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36708245   
OrganismHomo sapiens
Experiment descriptionFaeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases
AuthorsFizanne L, Villard A, Benabbou N, Recoquillon S, Soleti R, Delage E, Wertheimer M, Vidal-Gómez X, Oullier T, Chaffron S, Martínez MC, Neunlist M, Boursier J, Andriantsitohaina R.
Journal name J Extracell Vesicles
Publication year2023
SampleFaeces
Sample nameControl - non-NAFLD/non-NASH donor
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyPierce Chromogenic Endotoxin Quant Kit
Western blotting
EV-TRACK -

4
Experiment ID2356
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36708245   
OrganismHomo sapiens
Experiment descriptionFaeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases
AuthorsFizanne L, Villard A, Benabbou N, Recoquillon S, Soleti R, Delage E, Wertheimer M, Vidal-Gómez X, Oullier T, Chaffron S, Martínez MC, Neunlist M, Boursier J, Andriantsitohaina R.
Journal name J Extracell Vesicles
Publication year2023
SampleFaeces
Sample nameNAFLD patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyPierce Chromogenic Endotoxin Quant Kit
Western blotting
EV-TRACK -

5
Experiment ID2357
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36708245   
OrganismHomo sapiens
Experiment descriptionFaeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases
AuthorsFizanne L, Villard A, Benabbou N, Recoquillon S, Soleti R, Delage E, Wertheimer M, Vidal-Gómez X, Oullier T, Chaffron S, Martínez MC, Neunlist M, Boursier J, Andriantsitohaina R.
Journal name J Extracell Vesicles
Publication year2023
SampleFaeces
Sample nameNASH patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyPierce Chromogenic Endotoxin Quant Kit
Western blotting
EV-TRACK -

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