Gene description for CD81 |
Gene name |
CD81 molecule |
Gene symbol |
CD81 |
Other names/aliases |
CVID6 S5.7 TAPA1 TSPAN28 |
Species |
Homo sapiens |
Experiment description of studies that identified CD81 in Fibroblasts |
1
|
Experiment ID | 1803 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35917363
|
Organism | Homo sapiens |
Experiment description | CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness |
Authors | Nigri J, Leca J, Tubiana SS, Finetti P, Guillaumond F, Martinez S, Lac S, Iovanna JL, Audebert S, Camoin L, Vasseur S, Bertucci F, Tomasini R. |
Journal name |
Sci Signal
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | CAF - Pancreatic ductal adenocarcinoma |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1804 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35917363
|
Organism | Homo sapiens |
Experiment description | CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness |
Authors | Nigri J, Leca J, Tubiana SS, Finetti P, Guillaumond F, Martinez S, Lac S, Iovanna JL, Audebert S, Camoin L, Vasseur S, Bertucci F, Tomasini R. |
Journal name |
Sci Signal
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | CAF - Pancreatic ductal adenocarcinoma |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 1899 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1900 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1901 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | BJ |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1902 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | BJ |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1903 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1904 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1905 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1906 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1907 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 1908 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 1909 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 1910 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
15
|
Experiment ID | 1911 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36266345
|
Organism | Homo sapiens |
Experiment description | Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression |
Authors | Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Fibroblasts |
Sample name | MRC-5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
16
|
Experiment ID | 3150 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
29438363
|
Organism | Homo sapiens |
Experiment description | CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells |
Authors | Miki Y, Yashiro M, Okuno T, Kitayama K, Masuda G, Hirakawa K, Ohira M. |
Journal name |
Br J Cancer
|
Publication year | 2018 |
Sample | Fibroblasts |
Sample name | NF65 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
17
|
Experiment ID | 3036 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
33893753
|
Organism | Homo sapiens |
Experiment description | Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy |
Authors | Roberto J, Poulin KL, Parks RJ, Vacratsis PO. |
Journal name |
Proteomics
|
Publication year | 2021 |
Sample | Fibroblasts |
Sample name | GM03813 - SMA type 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 3037 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
33893753
|
Organism | Homo sapiens |
Experiment description | Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy |
Authors | Roberto J, Poulin KL, Parks RJ, Vacratsis PO. |
Journal name |
Proteomics
|
Publication year | 2021 |
Sample | Fibroblasts |
Sample name | GM03814 - Normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|