Gene description for CPNE8
Gene name	copine VIII
Gene symbol	CPNE8
Other names/aliases	-
Species	Homo sapiens
Database cross references - CPNE8
Vesiclepedia	VP_144402
ExoCarta	ExoCarta_144402
Entrez Gene	144402
HGNC	23498
CPNE8 identified in extracellular vesicles derived from the following tissue/cell type
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	26378940
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Dendritic cells [Exosomes]      More >>>	26858453
Dendritic cells [Extracellular vesicles]      More >>>	26858453
Dendritic cells [Extracellular vesicles]      More >>>	26858453
Epithelial cells [Exosomes]      More >>>	25776846
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Prostate cancer cells [Extracellular vesicles]      More >>>	27894104
Prostate cancer cells [Extracellular vesicles]      More >>>	27894104
Prostate cancer cells [Exosomes]      More >>>	25844599
Urine [Exosomes]      More >>>	15326289
Urine [Microparticles]      More >>>	18373357
Urine [Microparticles]      More >>>	18373357
Urine [Exosomes/Membrane particles]      More >>>	19158352
Urine [Exosomes/Membrane vesicles]      More >>>	22106071
Urine [Exosomes]      More >>>	22418980
Urine [Exosomes]      More >>>	22418980
Urine [Exosomes/Membrane vesicles]      More >>>	23082778
Urine [Exosomes/Membrane vesicles]      More >>>	23082778
Urine [Exosomes/Nanovesicles]      More >>>	23511837
Urine [Exosomes/Nanovesicles]      More >>>	23511837
Urine [Exosomes/Microvesicles]      More >>>	23533145
Urine [Exosomes/Microvesicles]      More >>>	23533145
Urine [Exosomes]      More >>>	25471207
Urine [Extracellular vesicles]      More >>>	29988836
Experiment description of studies that identified CPNE8 in extracellular vesicles
1 Experiment ID 80 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
2 Experiment ID 81 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
3 Experiment ID 581 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SF268 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
4 Experiment ID 576 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name HS 578T Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
5 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
6 Experiment ID 1029 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 26378940    Organism Homo sapiens Experiment description Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Authors Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. Journal name Anal Chem. Publication year 2015 Sample Breast cancer cells Sample name SKBR3B - 100 K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150004: EV-METRIC:67%, 38%
7 Experiment ID 1207 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 1 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
8 Experiment ID 1208 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 2 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
9 Experiment ID 1209 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 3 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
10 Experiment ID 1210 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 4 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
11 Experiment ID 1211 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 5 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
12 Experiment ID 589 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HCT-116 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
13 Experiment ID 564 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F3 100K) Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.11 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
14 Experiment ID 570 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ FUSION] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (CD63 PD) Isolation/purification methods Differential centrifugation Ultracentrifugation Immunobeads (CD63 PD) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ FUSION] EV-TRACK -
15 Experiment ID 572 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ FUSION] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (CD81 PD) Isolation/purification methods Differential centrifugation Ultracentrifugation Immunobeads (CD81 PD) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ FUSION] EV-TRACK -
16 Experiment ID 861 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25776846    Organism Homo sapiens Experiment description Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Authors Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. Journal name Immunol Cell Biol Publication year 2015 Sample Epithelial cells Sample name Thymic tissue - culture 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150045: EV-METRIC:25%
17 Experiment ID 595 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name A498 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
18 Experiment ID 596 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name ACHN Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
19 Experiment ID 597 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name CAKI Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
20 Experiment ID 598 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name RXF 393 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
21 Experiment ID 600 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name TK-10 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
22 Experiment ID 604 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name K562 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
23 Experiment ID 605 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name MOLT-4 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
24 Experiment ID 606 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name RPMI-8226 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
25 Experiment ID 607 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name SR Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
26 Experiment ID 609 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name EKVX Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
27 Experiment ID 610 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name HOP-62 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
28 Experiment ID 612 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H226 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
29 Experiment ID 616 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H522 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
30 Experiment ID 618 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name M14 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
31 Experiment ID 619 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MALME-3M Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
32 Experiment ID 621 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-2 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
33 Experiment ID 623 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-5 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
34 Experiment ID 492 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
35 Experiment ID 493 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
36 Experiment ID 628 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-4 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
37 Experiment ID 992 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
38 Experiment ID 993 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR433 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
39 Experiment ID 994 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR5 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
40 Experiment ID 995 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name SKOV3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
41 Experiment ID 633 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DU145 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
42 Experiment ID 634 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
43 Experiment ID 963 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Sen Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
44 Experiment ID 13 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 15326289    Organism Homo sapiens Experiment description Identification and proteomic profiling of exosomes in human urine. Authors Pisitkun T, Shen RF, Knepper MA Journal name PNAS Publication year 2004 Sample Urine Sample name Urine - Normal Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LCQ DECA XP] Western blotting EV-TRACK -
45 Experiment ID 382 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 18373357    Organism Homo sapiens Experiment description Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Authors Smalley DM, Sheman NE, Nelson K, Theodorescu D. Journal name J Proteome Res Publication year 2008 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
46 Experiment ID 383 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 18373357    Organism Homo sapiens Experiment description Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Authors Smalley DM, Sheman NE, Nelson K, Theodorescu D. Journal name J Proteome Res Publication year 2008 Sample Urine Sample name Patients of bladder cancer-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
47 Experiment ID 390 Identified molecule protein Extracellular vesicle type Exosomes/Membrane particles Identification method Mass spectrometry PubMed ID 19158352    Organism Homo sapiens Experiment description Characterization of PKD protein-positive exosome-like vesicles. Authors Hogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ. Journal name J Am Soc Nephrol Publication year 2009 Sample Urine Sample name Patients of autosomal recessive polycystic kidney disease-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
48 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120168: EV-METRIC:14%
49 Experiment ID 444 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 22418980    Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G. Journal name Kidney Int Publication year 2012 Sample Urine Sample name Normal_high density-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120083: EV-METRIC:22%
50 Experiment ID 445 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 22418980    Organism Homo sapiens Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G. Journal name Kidney Int Publication year 2012 Sample Urine Sample name Normal_low density-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120083: EV-METRIC:22%
51 Experiment ID 478 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of bladder cancer-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%
52 Experiment ID 479 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23082778    Organism Homo sapiens Experiment description Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Authors Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. Journal name J Proteome Res Publication year 2012 Sample Urine Sample name Patients of hernia-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120030: EV-METRIC:33%
53 Experiment ID 507 Identified molecule protein Extracellular vesicle type Exosomes/Nanovesicles Identification method Mass spectrometry PubMed ID 23511837    Organism Homo sapiens Experiment description Differential protein profiling of renal cell carcinoma urinary exosomes. Authors Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. Journal name Mol Biosyst Publication year 2013 Sample Urine Sample name Normal-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130016: EV-METRIC:44%
54 Experiment ID 508 Identified molecule protein Extracellular vesicle type Exosomes/Nanovesicles Identification method Mass spectrometry PubMed ID 23511837    Organism Homo sapiens Experiment description Differential protein profiling of renal cell carcinoma urinary exosomes. Authors Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. Journal name Mol Biosyst Publication year 2013 Sample Urine Sample name Renal cell carcinoma patient-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130016: EV-METRIC:44%
55 Experiment ID 512 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles Identification method Mass spectrometry PubMed ID 23533145    Organism Homo sapiens Experiment description In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Authors Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. Journal name Proteomics Publication year 2013 Sample Urine Sample name Low-grade prostate cancer patient-Expressed prostatic secretions in urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130224: EV-METRIC:14%
56 Experiment ID 513 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles Identification method Mass spectrometry PubMed ID 23533145    Organism Homo sapiens Experiment description In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Authors Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. Journal name Proteomics Publication year 2013 Sample Urine Sample name Normal-Expressed prostatic secretions in urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130224: EV-METRIC:14%
57 Experiment ID 725 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25471207    Organism Homo sapiens Experiment description Intraluminal proteome and peptidome of human urinary extracellular vesicles. Authors Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. Journal name Proteomics Clin Appl. Publication year 2015 Sample Urine Sample name Normal crude urine- Trypsinized Isolation/purification methods Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140189: EV-METRIC:25%
58 Experiment ID 751 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29988836    Organism Homo sapiens Experiment description Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Authors Oeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I. Journal name J Extracell Vesicles Publication year 2018 Sample Urine Sample name Urine - Fraction 8 and 9 pooled Isolation/purification methods Filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170025: EV-METRIC:62%