Gene description for CTNNB1
Gene name	catenin (cadherin-associated protein), beta 1, 88kDa
Gene symbol	CTNNB1
Other names/aliases	CTNNB
Species	Homo sapiens
Database cross references - CTNNB1
Vesiclepedia	VP_1499
ExoCarta	ExoCarta_1499
Entrez Gene	1499
HGNC	2514
MIM	116806
CTNNB1 identified in extracellular vesicles derived from the following tissue/cell type
Ascites [Microvesicles]      More >>>	21630462
Ascites [Microvesicles]      More >>>	21630462
Ascites [Microvesicles]      More >>>	21630462
Ascites [Microvesicles]      More >>>	21630462
Bladder cancer cells [Exosomes]      More >>>	20224111
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast milk [Extracellular vesicles]      More >>>	27601599
Colon cancer cells [Extracellular vesicles]      More >>>	27894104
Colon cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Exosomes]      More >>>	17956143
Colorectal cancer cells [Microvesicles]      More >>>	19930720
Colorectal cancer cells [Exosomes]      More >>>	22285593
Colorectal cancer cells [Exosomes]      More >>>	22285593
Colorectal cancer cells [Exosomes]      More >>>	22740476
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Dendritic cells [Exosomes]      More >>>	26858453
Dendritic cells [Exosomes]      More >>>	26858453
Endothelial cells [Microvesicles]      More >>>	17536014
Endothelial cells [Membrane vesicles/Extracellular vesicles]      More >>>	23436686
Endothelial cells [Exosomes/Extracellular vesicles]      More >>>	24009886
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles]      More >>>	23585444
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Mesenchymal stem cells [Exosomes]      More >>>	Unpublished / Not applicable
Mesenchymal stem cells [Microvesicles]      More >>>	22148876
Mesenchymal stem cells [Microvesicles]      More >>>	22148876
Mesenchymal stem cells [Microvesicles]      More >>>	22148876
Mesenchymal stem cells [Microvesicles]      More >>>	19389847
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Osteosarcoma cells [Matrix vesicles]      More >>>	21515422
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Prostate cancer cells [Exosomes]      More >>>	22030351
Saliva [Exosomes]      More >>>	19199708
Urine [Exosomes/Membrane vesicles]      More >>>	22106071
Experiment description of studies that identified CTNNB1 in extracellular vesicles
1 Experiment ID 160 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Western blotting PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Western blotting
2 Experiment ID 157 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer patient 1 Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
3 Experiment ID 158 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer patient 2 Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
4 Experiment ID 159 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer patient 3 Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
5 Experiment ID 76 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry Western blotting PubMed ID 20224111    Organism Homo sapiens Experiment description Proteomics analysis of bladder cancer exosomes. Authors Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. Journal name MCP Publication year 2010 Sample Bladder cancer cells Sample name HT1376 Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.10-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Western blotting FACS
6 Experiment ID 580 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name T-47D Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
7 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
8 Experiment ID 579 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MDA-MB-468 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
9 Experiment ID 574 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive] PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Authors Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name MCP Publication year 2016 Sample Breast milk Sample name Breast milk - normal Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry
10 Experiment ID 592 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colon cancer cells Sample name KM12 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
11 Experiment ID 593 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colon cancer cells Sample name SW620 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
12 Experiment ID 20 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry Western blotting PubMed ID 17956143    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells. Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS Journal name JPR Publication year 2007 Sample Colorectal cancer cells Sample name HT29 Isolation/purification methods Differential centrifugation Sucrose density gradient Diafiltration Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting
13 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration Optiprep density gradient Flotation density 1.098 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina]
14 Experiment ID 349 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Orbitrap] PubMed ID 22285593    Organism Homo sapiens Experiment description Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Authors Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ Journal name Methods Publication year 2012 Sample Colorectal cancer cells Sample name LIM1863 - OptiPrep density gradient Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient Flotation density Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting
15 Experiment ID 348 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Orbitrap] PubMed ID 22285593    Organism Homo sapiens Experiment description Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Authors Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ Journal name Methods Publication year 2012 Sample Colorectal cancer cells Sample name LIM1863 - EpCAM immunoaffinity Isolation/purification methods Differential centrifugation Filtration Immunobeads (EpCAM) Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting
16 Experiment ID 458 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 22740476    Organism Homo sapiens Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Authors Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ. Journal name Electrophoresis Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
17 Experiment ID 486 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
18 Experiment ID 487 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
19 Experiment ID 488 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Shed vesicles-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
20 Experiment ID 517 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
21 Experiment ID 518 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
22 Experiment ID 549 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
23 Experiment ID 550 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
24 Experiment ID 564 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Théry C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F3 100K) Isolation/purification methods Differential centrifugation Ultracenrifugation OptiPrep density gradient Flotation density 1.115 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
25 Experiment ID 565 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ ORBITRAP] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Théry C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F5 100K) Isolation/purification methods Differential centrifugation Ultracenrifugation OptiPrep density gradient Flotation density 1.145 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ ORBITRAP]
26 Experiment ID 309 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method RT-PCR PubMed ID 17536014    Organism Homo sapiens Experiment description Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Authors Deregibus MC, Cantaluppi V, Calogero R, Lo Iacono M, Tetta C, Biancone L, Bruno S, Bussolati B, Camussi G Journal name Blood Publication year 2007 Sample Endothelial cells Sample name Endothelial cells - Healthy donors Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein mRNA Methods used in the study FACS RT-PCR Microarray [Illumina]
27 Experiment ID 502 Identified molecule protein Extracellular vesicle type Membrane vesicles/Extracellular vesicles Identification method Mass spectrometry PubMed ID 23436686    Organism Homo sapiens Experiment description A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Authors Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. Journal name Proteomics Publication year 2013 Sample Endothelial cells Sample name Serum-starved-Human umbilical vascular endothelial cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
28 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
29 Experiment ID 595 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name A498 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
30 Experiment ID 596 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name ACHN Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
31 Experiment ID 598 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name RXF 393 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
32 Experiment ID 600 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name TK-10 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
33 Experiment ID 601 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name UO-31 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
34 Experiment ID 602 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name CCRF-CEM Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
35 Experiment ID 604 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name K562 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
36 Experiment ID 606 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name RPMI-8226 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
37 Experiment ID 607 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name SR Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
38 Experiment ID 608 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name A549 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
39 Experiment ID 616 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H522 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
40 Experiment ID 519 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Ectosomes/Microparticles Identification method Mass spectrometry PubMed ID 23585444    Organism Homo sapiens Experiment description Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Authors Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. Journal name Proteomics Publication year 2013 Sample Malignant pleural effusions Sample name Non-small cell lung cancer patient-Lung cancer pleural effusion Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
41 Experiment ID 617 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name LOX IMVI Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
42 Experiment ID 620 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MDA-MB-435 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
43 Experiment ID 621 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-2 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
44 Experiment ID 126 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ-FT Ultra] PubMed ID Unpublished / Not applicable Organism Homo sapiens Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim Journal name Mesenchymal Stem Cell Therapy Publication year 2011 Sample Mesenchymal stem cells Sample name huES9.E1 Isolation/purification methods HPLC Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Antibody array Mass spectrometry
45 Experiment ID 244 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry[Q-TOF] PubMed ID 22148876    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human mesenchymal stem cells Authors Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW Journal name J Proteome Res Publication year 2011 Sample Mesenchymal stem cells Sample name Mesenchymal stem cells - Rep 1 Isolation/purification methods Differential centrifugation Ultrafiltration Ultracentrifugation Sucrose density gradient Optiprep density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry[QTOF]
46 Experiment ID 310 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry[Q-TOF] PubMed ID 22148876    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human mesenchymal stem cells Authors Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW Journal name J Proteome Res Publication year 2011 Sample Mesenchymal stem cells Sample name Mesenchymal stem cells - Rep 2 Isolation/purification methods Differential centrifugation Ultrafiltration Ultracentrifugation Sucrose density gradient Optiprep density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry[QTOF]
47 Experiment ID 311 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry[Q-TOF] PubMed ID 22148876    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human mesenchymal stem cells Authors Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW Journal name J Proteome Res Publication year 2011 Sample Mesenchymal stem cells Sample name Mesenchymal stem cells - Rep 3 Isolation/purification methods Differential centrifugation Ultrafiltration Ultracentrifugation Sucrose density gradient Optiprep density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry[QTOF]
48 Experiment ID 394 Identified molecule mRNA Extracellular vesicle type Microvesicles Identification method Microarray PubMed ID 19389847    Organism Homo sapiens Experiment description Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. Authors Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, Tetta C, Camussi G. Journal name J Am Soc Nephrol Publication year 2009 Sample Mesenchymal stem cells Sample name Normal-Mesenchymal stem cells Isolation/purification methods - Flotation density - Molecules identified in the study mRNA Methods used in the study Microarray
49 Experiment ID 467 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_exosome-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
50 Experiment ID 468 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_microparticle-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
51 Experiment ID 428 Identified molecule protein Extracellular vesicle type Matrix vesicles Identification method Mass spectrometry PubMed ID 21515422    Organism Homo sapiens Experiment description Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. Authors Thouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S. Journal name J Proteomics Publication year 2011 Sample Osteosarcoma cells Sample name Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
52 Experiment ID 492 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
53 Experiment ID 493 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry
54 Experiment ID 626 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
55 Experiment ID 628 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-4 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
56 Experiment ID 630 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-8 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
57 Experiment ID 631 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name SK-OV-3 Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
58 Experiment ID 632 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name NCI-ADR-RES Isolation/purification methods Serum-free medium Differential centrifugation polymer-based precipitation Ultracenrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ]
59 Experiment ID 277 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Q-TOF] PubMed ID 22030351    Organism Homo sapiens Experiment description Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Authors Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM Journal name MCP Publication year 2011 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF]
60 Experiment ID 66 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 19199708    Organism Homo sapiens Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR Journal name JPR Publication year 2009 Sample Saliva Sample name Saliva Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting Immunoelectron microscopy
61 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry