Gene description for Krt1
Gene name keratin 1
Gene symbol Krt1
Other names/aliases Krt-2.1
Krt2-1
Krt86
Species Mus musculus
 Database cross references - Krt1
Vesiclepedia VP_16678
ExoCarta ExoCarta_16678
Entrez Gene 16678
 Krt1 identified in extracellular vesicles derived from the following tissue/cell type
Breast cancer cells [Exosomes]      More >>> 29115712   
Breast cancer cells [Exosomes]      More >>> 29115712   
Breast cancer cells [Exosomes]      More >>> 29115712   
Breast cancer cells [Exosomes]      More >>> 29115712   
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>> 30035390   
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>> 30035390   
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>> 30035390   
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>> 30035390   
Myeloid-derived suppressor cells [Exosomes]      More >>> 24295599   
Myeloid-derived suppressor cells [Exosomes]      More >>> 24295599   
Oligodendrocytes [Exosomes]      More >>> 21136642   
Oligodendrocytes [Exosomes]      More >>> 21136642   
 Experiment description of studies that identified Krt1 in extracellular vesicles
1
Experiment ID1051
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29115712   
OrganismMus musculus
Experiment descriptionProteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
AuthorsGangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleBreast cancer cells
Sample name67NR
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
2
Experiment ID1052
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29115712   
OrganismMus musculus
Experiment descriptionProteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
AuthorsGangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleBreast cancer cells
Sample name66cl4
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
3
Experiment ID1053
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29115712   
OrganismMus musculus
Experiment descriptionProteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
AuthorsGangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleBreast cancer cells
Sample name4T1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -
4
Experiment ID1054
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 29115712   
OrganismMus musculus
Experiment descriptionProteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
AuthorsGangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S.
Journal name Proteomics.
Publication year2017
SampleBreast cancer cells
Sample name4T1.2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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5
Experiment ID1055
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30035390   
OrganismMus musculus
Experiment descriptionArrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.
AuthorsAnand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S.
Journal name Proteomics.
Publication year2018
SampleMouse embryonic fibroblasts
Sample nameMEFs - WT 10K
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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6
Experiment ID1056
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30035390   
OrganismMus musculus
Experiment descriptionArrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.
AuthorsAnand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S.
Journal name Proteomics.
Publication year2018
SampleMouse embryonic fibroblasts
Sample nameMEFs - WT exosomes
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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7
Experiment ID1057
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30035390   
OrganismMus musculus
Experiment descriptionArrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.
AuthorsAnand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S.
Journal name Proteomics.
Publication year2018
SampleMouse embryonic fibroblasts
Sample nameMEFs - Arrdc1 KO 10K
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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8
Experiment ID1058
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 30035390   
OrganismMus musculus
Experiment descriptionArrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.
AuthorsAnand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S.
Journal name Proteomics.
Publication year2018
SampleMouse embryonic fibroblasts
Sample nameMEFs - Arrdc1 KO exosomes
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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9
Experiment ID1126
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24295599   
OrganismMus musculus
Experiment descriptionExosomes from myeloid-derived suppressor cells carry biologically active proteins.
AuthorsBurke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C.
Journal name J Proteome Res
Publication year2014
SampleMyeloid-derived suppressor cells
Sample nameConventional MDSC's-BALB/c mice injected with 4T1 cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140063: EV-METRIC:71%
10
Experiment ID1127
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 24295599   
OrganismMus musculus
Experiment descriptionExosomes from myeloid-derived suppressor cells carry biologically active proteins.
AuthorsBurke M, Choksawangkarn W, Edwards N, Ostrand-Rosenberg S, Fenselau C.
Journal name J Proteome Res
Publication year2014
SampleMyeloid-derived suppressor cells
Sample nameInflammatory MDSC's-BALB/c mice injected with 4T1 cells expressing IL-1.
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140063: EV-METRIC:71%
11
Experiment ID33
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 21136642   
OrganismMus musculus
Experiment descriptionOligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
AuthorsEva-Maria Krär-Albers, Niko Bretz, Stefan Tenzer, Christine Winterstein, Wiebke Mös, Hendrik Berger, Klaus-Armin Nave, HansjöSchild, Jacqueline Trotter
Journal name PROTEOMICS_CL
Publication year2007
SampleOligodendrocytes
Sample nameOligodendrocytes
Oli-neu
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density1.10-1.14 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [QTOF]
Western blotting
Immunoelectron microscopy
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12
Experiment ID419
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 21136642   
OrganismMus musculus
Experiment descriptionOligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
AuthorsKrÃmer-Albers EM, Bretz N, Tenzer S, Winterstein C, Möbius W, Berger H, Nave KA, Schild H, Trotter J.
Journal name Proteomics Clin Appl
Publication year2007
SampleOligodendrocytes
Sample nameNormal-Oligodendrocytes
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
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