Gene description for ACSL4
Gene name	acyl-CoA synthetase long-chain family member 4
Gene symbol	ACSL4
Other names/aliases	ACS4 FACL4 LACS4 MRX63 MRX68
Species	Homo sapiens
Database cross references - ACSL4
Vesiclepedia	VP_2182
ExoCarta	ExoCarta_2182
Entrez Gene	2182
HGNC	3571
MIM	300157
ACSL4 identified in extracellular vesicles derived from the following tissue/cell type
Ascites [Microvesicles]      More >>>	21630462
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast milk [Extracellular vesicles]      More >>>	27601599
Breast milk [Extracellular vesicles]      More >>>	27601599
Breast milk [Extracellular vesicles]      More >>>	27601599
Breast milk [Extracellular vesicles]      More >>>	27601599
Breast milk [Extracellular vesicles]      More >>>	27601599
Breast milk [Extracellular vesicles]      More >>>	27601599
Chronic lymphocytic leukemia cells [Exosomes]      More >>>	26100252
Colorectal cancer cells [Microvesicles]      More >>>	19930720
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Dendritic cells [Microvesicles]      More >>>	26858453
Dendritic cells [Microvesicles]      More >>>	26858453
Dendritic cells [Exosomes]      More >>>	26858453
Dendritic cells [Exosomes]      More >>>	26858453
Endothelial cells [Exosomes/Extracellular vesicles]      More >>>	24009886
Glioblastoma cells [Microvesicles]      More >>>	19011622
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles]      More >>>	23585444
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Mesenchymal stem cells [Microvesicles]      More >>>	22148876
Mesenchymal stem cells [Microvesicles]      More >>>	22148876
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Prostate cancer cells [Exosomes]      More >>>	24371517
Prostate cancer cells [Exosomes]      More >>>	24371517
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
Red blood cells [Microvesicles/Nanovesicles]      More >>>	18346024
T cells [Microvesicles]      More >>>	28811610
T cells [Exosomes]      More >>>	28811610
T cells [Microvesicles]      More >>>	28811610
T cells [Apoptotic bodies]      More >>>	28811610
T cells [Exosomes]      More >>>	23463506
T cells [Exosomes]      More >>>	23463506
Thymus [Exosomes]      More >>>	23844026
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Urine [Exosomes]      More >>>	19056867
Urine [Exosomes/Membrane vesicles]      More >>>	22106071
Urine [Exosomes]      More >>>	25471207
Urine [Extracellular vesicles]      More >>>	29988836
Experiment description of studies that identified ACSL4 in extracellular vesicles
1 Experiment ID 159 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer patient 3 Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK EV110017: EV-METRIC:38%
2 Experiment ID 1059 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1060 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 2 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 1061 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 3 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
5 Experiment ID 1062 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
6 Experiment ID 1063 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 2 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
7 Experiment ID 1064 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 3 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
8 Experiment ID 79 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
9 Experiment ID 80 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
10 Experiment ID 81 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
11 Experiment ID 905 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
12 Experiment ID 930 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
13 Experiment ID 580 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name T-47D Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
14 Experiment ID 582 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SF295 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
15 Experiment ID 586 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name U251 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
16 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
17 Experiment ID 574 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive] PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Authors Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name MCP Publication year 2016 Sample Breast milk Sample name Breast milk - normal Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
18 Experiment ID 950 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
19 Experiment ID 951 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
20 Experiment ID 952 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
21 Experiment ID 956 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - D7 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV160000: EV-METRIC:50%
22 Experiment ID 957 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 27601599    Organism Homo sapiens Experiment description Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Authors van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH Journal name Mol Cell Proteomics Publication year 2016 Sample Breast milk Sample name Milk - derived EVs - pooled Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV160000: EV-METRIC:50%
23 Experiment ID 902 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name MEC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS Western blotting EV-TRACK EV150015: EV-METRIC:22%, 44%
24 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina] EV-TRACK -
25 Experiment ID 517 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
26 Experiment ID 518 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
27 Experiment ID 549 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
28 Experiment ID 550 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
29 Experiment ID 588 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HCC 2998 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
30 Experiment ID 592 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name KM12 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
31 Experiment ID 696 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- insulin induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
32 Experiment ID 697 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- non-induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
33 Experiment ID 1049 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215 - NI Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
34 Experiment ID 1050 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name lim1215 - II Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
35 Experiment ID 562 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F3 10K) Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.11 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
36 Experiment ID 563 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F5 10K) Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.14 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
37 Experiment ID 564 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F3 100K) Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.11 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
38 Experiment ID 565 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ ORBITRAP] PubMed ID 26858453    Organism Homo sapiens Experiment description Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Authors Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C Journal name PNAS Publication year 2016 Sample Dendritic cells Sample name monocyte-derived dendritic cells (F5 100K) Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.14 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ ORBITRAP] EV-TRACK -
39 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%
40 Experiment ID 203 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray PubMed ID 19011622    Organism Homo sapiens Experiment description Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Authors Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO Journal name Nat Cell Biol Publication year 2008 Sample Glioblastoma cells Sample name Glioblastoma cells Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA mRNA Methods used in the study RT-PCR Antibody array Microarray EV-TRACK -
41 Experiment ID 597 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name CAKI Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
42 Experiment ID 599 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name SN12C Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
43 Experiment ID 600 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name TK-10 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
44 Experiment ID 519 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Ectosomes/Microparticles Identification method Mass spectrometry PubMed ID 23585444    Organism Homo sapiens Experiment description Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Authors Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. Journal name Proteomics Publication year 2013 Sample Malignant pleural effusions Sample name Non-small cell lung cancer patient-Lung cancer pleural effusion Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130049: EV-METRIC:38%
45 Experiment ID 622 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-28 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
46 Experiment ID 244 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry[Q-TOF] PubMed ID 22148876    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human mesenchymal stem cells Authors Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW Journal name J Proteome Res Publication year 2011 Sample Mesenchymal stem cells Sample name Mesenchymal stem cells - Rep 1 Isolation/purification methods Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry[QTOF] EV-TRACK -
47 Experiment ID 310 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry[Q-TOF] PubMed ID 22148876    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human mesenchymal stem cells Authors Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW Journal name J Proteome Res Publication year 2011 Sample Mesenchymal stem cells Sample name Mesenchymal stem cells - Rep 2 Isolation/purification methods Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry[QTOF] EV-TRACK -
48 Experiment ID 467 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_exosome-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
49 Experiment ID 468 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_microparticle-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
50 Experiment ID 492 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
51 Experiment ID 493 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
52 Experiment ID 626 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
53 Experiment ID 628 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-4 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
54 Experiment ID 629 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-5 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
55 Experiment ID 631 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name SK-OV-3 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
56 Experiment ID 992 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
57 Experiment ID 993 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR433 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
58 Experiment ID 994 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR5 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
59 Experiment ID 995 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name SKOV3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
60 Experiment ID 1260 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24371517    Organism Homo sapiens Experiment description Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Authors Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. Journal name J Extracell Vesicles. Publication year 2013 Sample Prostate cancer cells Sample name LNCaP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130168: EV-METRIC:11%, 11%
61 Experiment ID 1261 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24371517    Organism Homo sapiens Experiment description Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Authors Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. Journal name J Extracell Vesicles. Publication year 2013 Sample Prostate cancer cells Sample name PC3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130168: EV-METRIC:11%, 11%
62 Experiment ID 376 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Microvesicle, Storage day 21-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
63 Experiment ID 377 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Microvesicle, Storage day 3-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
64 Experiment ID 378 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Microvesicle, Storage day 42-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
65 Experiment ID 379 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Nanovesicle, Storage day 21-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
66 Experiment ID 380 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Nanovesicle, Storage day 3-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
67 Experiment ID 381 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 18346024    Organism Homo sapiens Experiment description The proteome of red cell membranes and vesicles during storage in blood bank conditions. Authors Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. Journal name Transfusion Publication year 2008 Sample Red blood cells Sample name Nanovesicle, Storage day 42-Red blood cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
68 Experiment ID 708 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Control Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
69 Experiment ID 710 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Activated Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
70 Experiment ID 714 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Apoptotic Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
71 Experiment ID 715 Identified molecule protein Extracellular vesicle type Apoptotic bodies Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Apoptotic Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
72 Experiment ID 1004 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts - exosomes pulldown with CD81 as a bait Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130110: EV-METRIC:22%
73 Experiment ID 1008 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130110: EV-METRIC:22%
74 Experiment ID 538 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23844026    Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130018: EV-METRIC:63%
75 Experiment ID 680 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
76 Experiment ID 681 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
77 Experiment ID 682 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
78 Experiment ID 683 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
79 Experiment ID 684 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
80 Experiment ID 685 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
81 Experiment ID 63 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 19056867    Organism Homo sapiens Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes. Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA Journal name JASN Publication year 2009 Sample Urine Sample name Urine - Normal Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting EV-TRACK -
82 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120168: EV-METRIC:14%
83 Experiment ID 725 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25471207    Organism Homo sapiens Experiment description Intraluminal proteome and peptidome of human urinary extracellular vesicles. Authors Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. Journal name Proteomics Clin Appl. Publication year 2015 Sample Urine Sample name Normal crude urine- Trypsinized Isolation/purification methods Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140189: EV-METRIC:25%
84 Experiment ID 751 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29988836    Organism Homo sapiens Experiment description Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Authors Oeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I. Journal name J Extracell Vesicles Publication year 2018 Sample Urine Sample name Urine - Fraction 8 and 9 pooled Isolation/purification methods Filtration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170025: EV-METRIC:62%