Gene description for GPC1
Gene name	glypican 1
Gene symbol	GPC1
Other names/aliases	glypican
Species	Homo sapiens
Database cross references - GPC1
Vesiclepedia	VP_2817
ExoCarta	ExoCarta_2817
Entrez Gene	2817
HGNC	4449
MIM	600395
GPC1 identified in extracellular vesicles derived from the following tissue/cell type
Ascites [Microvesicles]      More >>>	21630462
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Colorectal cancer cells [Microvesicles]      More >>>	19930720
Colorectal cancer cells [Exosomes]      More >>>	23161513
Colorectal cancer cells [Exosomes]      More >>>	23161513
Colorectal cancer cells [Exosomes]      More >>>	23161513
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Endothelial cells [Exosomes/Extracellular vesicles]      More >>>	24009886
Epithelial cells [Exosomes]      More >>>	25776846
Glioblastoma cells [Microvesicles]      More >>>	19011622
Glioblastoma cells [Exosomes]      More >>>	25802036
Glioblastoma cells [Exosomes]      More >>>	25261722
Keratinocytes [Exosomes]      More >>>	19530224
Keratinocytes [Exosomes]      More >>>	19530224
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cells [Exosomes/Extracellular vesicles]      More >>>	23645497
Kidney cells [Exosomes/Extracellular vesicles]      More >>>	23645497
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Mesenchymal stem cells [Exosomes]      More >>>	Unpublished / Not applicable
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Prostate cancer cells [Extracellular vesicles]      More >>>	27894104
Prostate cancer cells [Exosomes]      More >>>	25844599
Prostate cancer cells [Exosomes]      More >>>	25844599
Prostate cancer cells [Exosomes]      More >>>	24371517
Prostate cancer cells [Exosomes]      More >>>	24371517
Retinal pigment epithelial cells [Exosomes]      More >>>	24400796
Saliva [Exosomes]      More >>>	19199708
Squamous carcinoma cells [Exosomes]      More >>>	20124223
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Urine [Exosomes/Membrane vesicles]      More >>>	22106071
Urine [Exosomes/Membrane vesicles]      More >>>	23376485
Experiment description of studies that identified GPC1 in extracellular vesicles
1 Experiment ID 159 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [LTQ] PubMed ID 21630462    Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer ascites Authors Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS Journal name Proteomics Publication year 2011 Sample Ascites Sample name Malignant ascites - Colorectal cancer patient 3 Isolation/purification methods Differential centrifugation Sucrose density gradient OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK EV110017: EV-METRIC:38%
2 Experiment ID 1059 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1060 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 2 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 1061 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 3 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
5 Experiment ID 905 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
6 Experiment ID 930 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
7 Experiment ID 580 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name T-47D Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
8 Experiment ID 581 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SF268 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
9 Experiment ID 584 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SNB-19 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
10 Experiment ID 585 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SNB-75 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
11 Experiment ID 586 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name U251 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
12 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
13 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
14 Experiment ID 578 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
15 Experiment ID 1207 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 1 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
16 Experiment ID 1208 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 2 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
17 Experiment ID 1209 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 3 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
18 Experiment ID 1210 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 4 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
19 Experiment ID 1211 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 5 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
20 Experiment ID 1212 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultracentrifugation, sample 1 Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
21 Experiment ID 1213 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultracentrifugation, sample 2 Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
22 Experiment ID 1214 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultracentrifugation, sample 3 Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
23 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina] EV-TRACK -
24 Experiment ID 480 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23161513    Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130004: EV-METRIC:44%
25 Experiment ID 481 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23161513    Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130004: EV-METRIC:44%
26 Experiment ID 482 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23161513    Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130004: EV-METRIC:44%
27 Experiment ID 517 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
28 Experiment ID 518 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
29 Experiment ID 549 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
30 Experiment ID 550 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
31 Experiment ID 588 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HCC 2998 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
32 Experiment ID 592 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name KM12 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
33 Experiment ID 696 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- insulin induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
34 Experiment ID 697 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- non-induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
35 Experiment ID 1049 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215 - NI Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
36 Experiment ID 1050 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name lim1215 - II Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
37 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%
38 Experiment ID 862 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25776846    Organism Homo sapiens Experiment description Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Authors Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. Journal name Immunol Cell Biol Publication year 2015 Sample Epithelial cells Sample name Thymic tissue - culture 2 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150045: EV-METRIC:25%
39 Experiment ID 203 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray PubMed ID 19011622    Organism Homo sapiens Experiment description Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Authors Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO Journal name Nat Cell Biol Publication year 2008 Sample Glioblastoma cells Sample name Glioblastoma cells Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA mRNA Methods used in the study RT-PCR Antibody array Microarray EV-TRACK -
40 Experiment ID 723 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25802036    Organism Homo sapiens Experiment description Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Authors de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. Journal name Int J Cancer Publication year 2015 Sample Glioblastoma cells Sample name GS184 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150064: EV-METRIC:0%, 0%, 29%
41 Experiment ID 1242 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25261722    Organism Homo sapiens Experiment description Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Authors Kore RA, Abraham EC. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Glioblastoma cells Sample name U373 cells treated with 10ng/ml of IL-1. Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140183: EV-METRIC:22%
42 Experiment ID 398 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 19530224    Organism Homo sapiens Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Authors Chavez-Muñoz C, Kilani RT, Ghahary A. Journal name J Cell Physiol Publication year 2009 Sample Keratinocytes Sample name Differentiated-Keratinocytes Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
43 Experiment ID 399 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 19530224    Organism Homo sapiens Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Authors Chavez-Muñoz C, Kilani RT, Ghahary A. Journal name J Cell Physiol Publication year 2009 Sample Keratinocytes Sample name Undifferentiated-Keratinocytes Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
44 Experiment ID 594 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name 786-O Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
45 Experiment ID 521 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 23645497    Organism Canis lupus familiaris Experiment description Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Authors Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2013 Sample Kidney cells Sample name Normal-Madin-Darby canine kidney cell (MDCK) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130021: EV-METRIC:50%
46 Experiment ID 522 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 23645497    Organism Canis lupus familiaris Experiment description Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Authors Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2013 Sample Kidney cells Sample name Ras-transformed MDCK cells (21D1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130021: EV-METRIC:50%
47 Experiment ID 602 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name CCRF-CEM Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
48 Experiment ID 612 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H226 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
49 Experiment ID 889 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
50 Experiment ID 890 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
51 Experiment ID 891 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
52 Experiment ID 893 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
53 Experiment ID 894 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
54 Experiment ID 895 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
55 Experiment ID 619 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MALME-3M Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
56 Experiment ID 126 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [LTQ-FT Ultra] PubMed ID Unpublished / Not applicable Organism Homo sapiens Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim Journal name Mesenchymal Stem Cell Therapy Publication year 2011 Sample Mesenchymal stem cells Sample name huES9.E1 Isolation/purification methods HPLC Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Antibody array Mass spectrometry EV-TRACK -
57 Experiment ID 467 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_exosome-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
58 Experiment ID 468 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_microparticle-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
59 Experiment ID 627 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
60 Experiment ID 992 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
61 Experiment ID 993 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR433 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
62 Experiment ID 994 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR5 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
63 Experiment ID 995 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name SKOV3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
64 Experiment ID 633 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DU145 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
65 Experiment ID 963 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Sen Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
66 Experiment ID 964 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Res Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.13-1.18 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
67 Experiment ID 1260 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24371517    Organism Homo sapiens Experiment description Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Authors Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. Journal name J Extracell Vesicles. Publication year 2013 Sample Prostate cancer cells Sample name LNCaP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130168: EV-METRIC:11%, 11%
68 Experiment ID 1261 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24371517    Organism Homo sapiens Experiment description Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Authors Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. Journal name J Extracell Vesicles. Publication year 2013 Sample Prostate cancer cells Sample name PC3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130168: EV-METRIC:11%, 11%
69 Experiment ID 1256 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24400796    Organism Homo sapiens Experiment description Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Authors Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. Journal name J Proteome Res. Publication year 2014 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140174: EV-METRIC:13%, 13%
70 Experiment ID 66 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 19199708    Organism Homo sapiens Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR Journal name JPR Publication year 2009 Sample Saliva Sample name Saliva Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting Immunoelectron microscopy EV-TRACK -
71 Experiment ID 411 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20124223    Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV100050: EV-METRIC:22%
72 Experiment ID 680 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
73 Experiment ID 681 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
74 Experiment ID 682 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
75 Experiment ID 683 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
76 Experiment ID 685 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
77 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120168: EV-METRIC:14%
78 Experiment ID 498 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23376485    Organism Homo sapiens Experiment description Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Authors Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S. Journal name J Proteomics Publication year 2013 Sample Urine Sample name Normal-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130051: EV-METRIC:38%