Gene description for EHD4 |
Gene name |
EH-domain containing 4 |
Gene symbol |
EHD4 |
Other names/aliases |
PAST4 |
Species |
Homo sapiens |
Database cross references - EHD4 |
Vesiclepedia |
VP_30844 |
ExoCarta |
ExoCarta_30844 |
Entrez Gene |
30844 |
HGNC |
3245 |
MIM |
605892 |
EHD4 identified in extracellular vesicles derived from the following tissue/cell type |
Ascites [Microvesicles] More >>>
|
21630462
|
Ascites [Microvesicles] More >>>
|
21630462
|
Ascites [Microvesicles] More >>>
|
21630462
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles] More >>>
|
23818640
|
Bladder cancer cells [Exosomes] More >>>
|
20224111
|
Bladder cancer cells [Extracellular vesicles] More >>>
|
29207636
|
Bladder cancer cells [Extracellular vesicles] More >>>
|
29207636
|
Bladder cancer cells [Extracellular vesicles] More >>>
|
29207636
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
26378940
|
Breast milk [Exosomes] More >>>
|
17641064
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Colorectal cancer cells [Exosomes] More >>>
|
17956143
|
Colorectal cancer cells [Exosomes] More >>>
|
19837982
|
Colorectal cancer cells [Microvesicles] More >>>
|
19930720
|
Colorectal cancer cells [Exosomes] More >>>
|
22740476
|
Colorectal cancer cells [Exosomes] More >>>
|
23161513
|
Colorectal cancer cells [Exosomes] More >>>
|
23161513
|
Colorectal cancer cells [Exosomes] More >>>
|
23161513
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Dendritic cells [Extracellular vesicles] More >>>
|
26858453
|
Duodenal cancer cells [Exosomes] More >>>
|
25065644
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
19369228
|
Endothelial cells [Membrane vesicles/Extracellular vesicles] More >>>
|
23436686
|
Endothelial cells [Exosomes/Extracellular vesicles] More >>>
|
24009886
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Glioblastoma cells [Microvesicles] More >>>
|
19011622
|
Glioblastoma cells [Exosomes] More >>>
|
25802036
|
Glioblastoma cells [Exosomes] More >>>
|
29937354
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles] More >>>
|
23585444
|
Melanoma cells [Exosomes] More >>>
|
22635005
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Mesenchymal stem cells [Exosomes] More >>>
|
Unpublished / Not applicable
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Osteosarcoma cells [Matrix vesicles] More >>>
|
21515422
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Plasma [Microparticles] More >>>
|
23056467
|
Platelets [Microparticles] More >>>
|
16212402
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Exosomes] More >>>
|
25102470
|
Prostate cancer cells [Exosomes] More >>>
|
25844599
|
Prostate cancer cells [Exosomes] More >>>
|
25844599
|
Prostate cancer cells [Exosomes] More >>>
|
24391718
|
Prostate cancer cells [Exosomes] More >>>
|
24391718
|
Prostate cancer cells [Exosomes] More >>>
|
24391718
|
Prostate cancer cells [Exosomes] More >>>
|
24371517
|
Prostate cancer cells [Exosomes] More >>>
|
24371517
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Prostate epithelial cells [Exosomes] More >>>
|
24391718
|
Seminal plasma [Prostasomes] More >>>
|
23707955
|
Squamous carcinoma cells [Exosomes] More >>>
|
20124223
|
Squamous carcinoma cells [Extracellular vesicles] More >>>
|
23954818
|
T cells [Exosomes] More >>>
|
23463506
|
T cells [Exosomes] More >>>
|
23463506
|
T cells [Exosomes] More >>>
|
23463506
|
Thymus [Exosomes] More >>>
|
23844026
|
Transitional carcinoma cells [Extracellular vesicles] More >>>
|
29207636
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Urine [Exosomes] More >>>
|
15326289
|
Urine [Exosomes] More >>>
|
19056867
|
Urine [Microparticles] More >>>
|
18373357
|
Urine [Microparticles] More >>>
|
18373357
|
Urine [Exosomes/Membrane particles] More >>>
|
19158352
|
Urine [Exosomes] More >>>
|
21595033
|
Urine [Exosomes] More >>>
|
21595033
|
Urine [Exosomes] More >>>
|
21595033
|
Urine [Exosomes/Membrane vesicles] More >>>
|
22106071
|
Urine [Exosomes] More >>>
|
22418980
|
Urine [Exosomes] More >>>
|
22418980
|
Urine [Exosomes/Membrane vesicles] More >>>
|
23082778
|
Urine [Exosomes/Membrane vesicles] More >>>
|
23082778
|
Urine [Exosomes/Membrane vesicles] More >>>
|
23376485
|
Urine [Exosomes/Nanovesicles] More >>>
|
23511837
|
Urine [Exosomes/Nanovesicles] More >>>
|
23511837
|
Urine [Exosomes/Microvesicles] More >>>
|
23533145
|
Urine [Exosomes/Microvesicles] More >>>
|
23533145
|
Urine [Exosomes/Microvesicles] More >>>
|
23886663
|
Urine [Exosomes] More >>>
|
25471207
|
Urine [Extracellular vesicles] More >>>
|
29988836
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urine [Extracellular vesicles] More >>>
|
29207636
|
Urothelial cells [Extracellular vesicles] More >>>
|
29207636
|
Urothelial cells [Extracellular vesicles] More >>>
|
29207636
|
Experiment description of studies that identified EHD4 in extracellular vesicles |
1
|
Experiment ID | 157 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 1 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
2
|
Experiment ID | 158 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 2 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
3
|
Experiment ID | 159 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 3 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
4
|
Experiment ID | 1059 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1060 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1061 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1062 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1063 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1064 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 79 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
11
|
Experiment ID | 80 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
12
|
Experiment ID | 81 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
13
|
Experiment ID | 534 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | EBV- and KSHV-infected B cells (JSC-1, BC1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
14
|
Experiment ID | 535 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | EBV-infected B cells (#1, HLJ, IM9, CP) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
15
|
Experiment ID | 536 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | KSHV-infected B cell (JC, BC3, BCP1, BCBL1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
16
|
Experiment ID | 537 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Oncosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23818640
|
Organism | Homo sapiens |
Experiment description | Modulation of B-cell exosome proteins by gamma herpesvirus infection. |
Authors | Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. |
Journal name |
Proc Natl Acad Sci U S A
|
Publication year | 2013 |
Sample | B cells |
Sample name | Normal B cells (BJAB) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130064: EV-METRIC:25%
|
|
|
17
|
Experiment ID | 76 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20224111
|
Organism | Homo sapiens |
Experiment description | Proteomics analysis of bladder cancer exosomes. |
Authors | Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. |
Journal name |
MCP
|
Publication year | 2010 |
Sample | Bladder cancer cells |
Sample name | HT1376 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.10-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Western blotting FACS |
EV-TRACK |
EV100014: EV-METRIC:38%, 14%, 44%
|
|
|
18
|
Experiment ID | 905 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Bladder cancer cells |
Sample name | TCCSUP |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
19
|
Experiment ID | 930 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Bladder cancer cells |
Sample name | TCCSUP |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
20
|
Experiment ID | 934 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Bladder cancer cells |
Sample name | T24 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
21
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
22
|
Experiment ID | 1029 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
26378940
|
Organism | Homo sapiens |
Experiment description | Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. |
Authors | Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. |
Journal name |
Anal Chem.
|
Publication year | 2015 |
Sample | Breast cancer cells |
Sample name | SKBR3B - 100 K pellet |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150004: EV-METRIC:67%, 38%
|
|
|
23
|
Experiment ID | 46 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
17641064
|
Organism | Homo sapiens |
Experiment description | Exosomes with immune modulatory features are present in human breast milk. |
Authors | Admyre C, Johansson SM, Qazi KR, FiléJJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year | 2007 |
Sample | Breast milk |
Sample name | Breast milk - colostrum |
Isolation/purification methods | Differential centrifugation Filtration Sucrose density gradient |
Flotation density | 1.10-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QSTAR] Western blotting Immunoelectron microscopy FACS |
EV-TRACK |
-
|
|
|
24
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
25
|
Experiment ID | 950 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
26
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
27
|
Experiment ID | 952 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
28
|
Experiment ID | 953 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D4 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
29
|
Experiment ID | 954 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
30
|
Experiment ID | 955 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D6 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
31
|
Experiment ID | 956 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
32
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
33
|
Experiment ID | 899 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | CLL cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
34
|
Experiment ID | 900 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | CLL cells - Rep 2 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
35
|
Experiment ID | 901 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | JVM-3 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
36
|
Experiment ID | 902 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | MEC-1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry FACS Western blotting |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
37
|
Experiment ID | 20 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
17956143
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer cells. |
Authors | Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS |
Journal name |
JPR
|
Publication year | 2007 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density | 1.16 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting |
EV-TRACK |
-
|
|
|
38
|
Experiment ID | 21 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry | |
Supporting data | |
MS
| |
PubMed ID |
19837982
|
Organism | Homo sapiens |
Experiment description | Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. |
Authors | Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson |
Journal name |
MCP
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | LIM1215 |
Isolation/purification methods | Filtration Ultracentrifugation Sucrose density gradient |
Flotation density | 1.10-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV100013: EV-METRIC:25%, 56%
|
|
|
39
|
Experiment ID | 303 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray [Illumina]
|
PubMed ID |
19930720
|
Organism | Homo sapiens |
Experiment description | Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells |
Authors | Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS |
Journal name |
BMC Genomics
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | Differential centrifugation Ultrafiltration OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein mRNA |
Methods used in the study | Western blotting RT-PCR Microarray [Illumina] |
EV-TRACK |
-
|
|
|
40
|
Experiment ID | 458 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22740476
|
Organism | Homo sapiens |
Experiment description | Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. |
Authors | Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ. |
Journal name |
Electrophoresis
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120074: EV-METRIC:11%
|
|
|
41
|
Experiment ID | 480 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23161513
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors | Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | DKO-1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130004: EV-METRIC:44%
|
|
|
42
|
Experiment ID | 481 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23161513
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors | Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Dks-8 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130004: EV-METRIC:44%
|
|
|
43
|
Experiment ID | 482 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23161513
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors | Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | DLD-1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130004: EV-METRIC:44%
|
|
|
44
|
Experiment ID | 487 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
45
|
Experiment ID | 488 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Shed vesicles-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
46
|
Experiment ID | 517 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
47
|
Experiment ID | 518 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
48
|
Experiment ID | 549 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
49
|
Experiment ID | 550 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
50
|
Experiment ID | 587 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | Colo205 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
51
|
Experiment ID | 588 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | HCC 2998 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
52
|
Experiment ID | 592 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | KM12 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
53
|
Experiment ID | 593 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
54
|
Experiment ID | 696 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- insulin induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
55
|
Experiment ID | 697 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- non-induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
56
|
Experiment ID | 1049 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215 - NI |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
57
|
Experiment ID | 1050 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | lim1215 - II |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
58
|
Experiment ID | 562 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
59
|
Experiment ID | 563 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
60
|
Experiment ID | 564 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
61
|
Experiment ID | 565 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ ORBITRAP]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ ORBITRAP] |
EV-TRACK |
-
|
|
|
62
|
Experiment ID | 567 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (Igg1 FT) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (Igg1 FT) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
63
|
Experiment ID | 568 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD9 PD) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD9 PD) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
64
|
Experiment ID | 569 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD9 FT) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD9 FT) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
65
|
Experiment ID | 570 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD63 PD) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD63 PD) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
66
|
Experiment ID | 571 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD63 FT) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD63 FT) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
67
|
Experiment ID | 572 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD81 PD) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD81 PD) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
68
|
Experiment ID | 573 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ FUSION]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (CD81 FT) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Immunobeads (CD81 FT) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ FUSION] |
EV-TRACK |
-
|
|
|
69
|
Experiment ID | 1086 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25065644
|
Organism | Homo sapiens |
Experiment description | Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. |
Authors | Ohshima K, Kanto K, Hatakeyama K, Ide T, Wakabayashi-Nakao K, Watanabe Y, Sakura N, Terashima M, Yamaguchi K, Mochizuki T. |
Journal name |
Proteomics
|
Publication year | 2014 |
Sample | Duodenal cancer cells |
Sample name | AZ-P7a (metastatic) |
Isolation/purification methods | Differential centrifugation Filtration Ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140088: EV-METRIC:44%
|
|
|
70
|
Experiment ID | 385 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
71
|
Experiment ID | 386 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by PAI-1-Endothelial cell (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
72
|
Experiment ID | 387 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by TNF-alpha-Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
73
|
Experiment ID | 393 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19369228
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. |
Authors | Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. |
Journal name |
Blood
|
Publication year | 2009 |
Sample | Endothelial cells |
Sample name | Normal-Endothelial progenitor cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
74
|
Experiment ID | 502 |
Identified molecule | protein
|
Extracellular vesicle type | Membrane vesicles/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23436686
|
Organism | Homo sapiens |
Experiment description | A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. |
Authors | Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Endothelial cells |
Sample name | Serum-starved-Human umbilical vascular endothelial cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130048: EV-METRIC:44%
|
|
|
75
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|
76
|
Experiment ID | 861 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
77
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
78
|
Experiment ID | 723 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25802036
|
Organism | Homo sapiens |
Experiment description | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. |
Authors | de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. |
Journal name |
Int J Cancer
|
Publication year | 2015 |
Sample | Glioblastoma cells |
Sample name | GS184 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150064: EV-METRIC:0%, 0%, 29%
|
|
|
79
|
Experiment ID | 1072 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Lethally irradiated GBM157 - apoExo - biorep2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
80
|
Experiment ID | 598 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | RXF 393 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
81
|
Experiment ID | 599 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | SN12C |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
82
|
Experiment ID | 600 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | TK-10 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
83
|
Experiment ID | 521 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Normal-Madin-Darby canine kidney cell (MDCK) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
84
|
Experiment ID | 522 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Ras-transformed MDCK cells (21D1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
85
|
Experiment ID | 602 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | CCRF-CEM |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
86
|
Experiment ID | 605 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | MOLT-4 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
87
|
Experiment ID | 606 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | RPMI-8226 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
88
|
Experiment ID | 612 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H226 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
89
|
Experiment ID | 615 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H460 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
90
|
Experiment ID | 519 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Ectosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23585444
|
Organism | Homo sapiens |
Experiment description | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. |
Authors | Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Malignant pleural effusions |
Sample name | Non-small cell lung cancer patient-Lung cancer pleural effusion |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130049: EV-METRIC:38%
|
|
|
91
|
Experiment ID | 453 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22635005
|
Organism | Homo sapiens |
Experiment description | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. |
Authors | Peinado H, Alecković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, GarcÃa-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. |
Journal name |
Nat Med
|
Publication year | 2012 |
Sample | Melanoma cells |
Sample name | B16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120019: EV-METRIC:44%, 44%, 44%
|
|
|
92
|
Experiment ID | 617 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | LOX IMVI |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
93
|
Experiment ID | 621 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-2 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
94
|
Experiment ID | 622 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-28 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
95
|
Experiment ID | 624 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | UACC-257 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
96
|
Experiment ID | 625 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | UACC-62 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
97
|
Experiment ID | 126 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
Unpublished / Not applicable
|
Organism | Homo sapiens |
Experiment description | Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? |
Authors | Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim |
Journal name |
Mesenchymal Stem Cell Therapy
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | huES9.E1 |
Isolation/purification methods | HPLC |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Antibody array Mass spectrometry |
EV-TRACK |
-
|
|
|
98
|
Experiment ID | 310 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 2 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
99
|
Experiment ID | 401 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
100
|
Experiment ID | 402 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by IgG-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
101
|
Experiment ID | 403 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by LPS-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
102
|
Experiment ID | 404 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by P-selectin-Ig-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
103
|
Experiment ID | 467 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_exosome-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
104
|
Experiment ID | 468 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_microparticle-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
105
|
Experiment ID | 428 |
Identified molecule | protein
|
Extracellular vesicle type | Matrix vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
21515422
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. |
Authors | Thouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S. |
Journal name |
J Proteomics
|
Publication year | 2011 |
Sample | Osteosarcoma cells |
Sample name | Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
106
|
Experiment ID | 492 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | IGROV1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
107
|
Experiment ID | 493 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-3 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
108
|
Experiment ID | 631 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | SK-OV-3 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
109
|
Experiment ID | 992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
110
|
Experiment ID | 993 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR433 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
111
|
Experiment ID | 994 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
112
|
Experiment ID | 995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | SKOV3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
113
|
Experiment ID | 473 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23056467
|
Organism | Homo sapiens |
Experiment description | Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. |
Authors | Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Patients of external counterpulsation therapy-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
114
|
Experiment ID | 369 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
16212402
|
Organism | Homo sapiens |
Experiment description | The platelet microparticle proteome. |
Authors | Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. |
Journal name |
J Proteome Res
|
Publication year | 2005 |
Sample | Platelets |
Sample name | Normal donors-Platelets |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
115
|
Experiment ID | 855 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS with DHT treatment - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
116
|
Experiment ID | 856 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS with DHT treatment - Rep 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
117
|
Experiment ID | 887 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25102470
|
Organism | Homo sapiens |
Experiment description | Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro |
Authors | Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ. |
Journal name |
Biochim Biophys Acta
|
Publication year | 2014 |
Sample | Prostate cancer cells |
Sample name | PC3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.10-1.20 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140013: EV-METRIC:56%
|
|
|
118
|
Experiment ID | 963 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25844599
|
Organism | Homo sapiens |
Experiment description | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors | Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | DU145 Tax-Sen |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150027: EV-METRIC:11%, 56%
|
|
|
119
|
Experiment ID | 964 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25844599
|
Organism | Homo sapiens |
Experiment description | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors | Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | DU145 Tax-Res |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.13-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150027: EV-METRIC:11%, 56%
|
|
|
120
|
Experiment ID | 1110 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | PC346C- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
121
|
Experiment ID | 1111 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | PC346C- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
122
|
Experiment ID | 1112 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | PC346C- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
123
|
Experiment ID | 1260 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24371517
|
Organism | Homo sapiens |
Experiment description | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. |
Authors | Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | LNCaP |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV130168: EV-METRIC:11%, 11%
|
|
|
124
|
Experiment ID | 1261 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24371517
|
Organism | Homo sapiens |
Experiment description | Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. |
Authors | Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2013 |
Sample | Prostate cancer cells |
Sample name | PC3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV130168: EV-METRIC:11%, 11%
|
|
|
125
|
Experiment ID | 1104 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
126
|
Experiment ID | 1105 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
127
|
Experiment ID | 1106 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | PNT2C2- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
128
|
Experiment ID | 1107 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
129
|
Experiment ID | 1108 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
130
|
Experiment ID | 1109 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24391718
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. |
Authors | Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Prostate epithelial cells |
Sample name | RWPE-1- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130038: EV-METRIC:33%
|
|
|
131
|
Experiment ID | 1138 |
Identified molecule | protein
|
Extracellular vesicle type | Prostasomes |
Identification method | Mass spectrometry
|
PubMed ID |
23707955
|
Organism | Homo sapiens |
Experiment description | Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). |
Authors | Ronquist KG, Ek B, Morrell J, Stavreus-Evers A, Ströolst B, Humblot P, Ronquist G, Larsson A. |
Journal name |
Biochim Biophys Acta
|
Publication year | 2013 |
Sample | Seminal plasma |
Sample name | normal male |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1-1.5 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130152: EV-METRIC:14%, 14%
|
|
|
132
|
Experiment ID | 411 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20124223
|
Organism | Homo sapiens |
Experiment description | Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. |
Authors | Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2010 |
Sample | Squamous carcinoma cells |
Sample name | Squamous carcinoma cell (A431) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV100050: EV-METRIC:22%
|
|
|
133
|
Experiment ID | 1129 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23954818
|
Organism | Homo sapiens |
Experiment description | Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. |
Authors | Garnier D, Magnus N, Meehan B, Kislinger T, Rak J. |
Journal name |
Exp Cell Res
|
Publication year | 2013 |
Sample | Squamous carcinoma cells |
Sample name | Mesenchymal A431 (SHE78-7/TGF. treated) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130185: EV-METRIC:11%
|
|
|
134
|
Experiment ID | 1004 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23463506
|
Organism | Homo sapiens |
Experiment description | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. |
Authors | Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartÃS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó |
Journal name |
J Biol Chem.
|
Publication year | 2013 |
Sample | T cells |
Sample name | T lymphoblasts - exosomes pulldown with CD81 as a bait |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV130110: EV-METRIC:22%
|
|
|
135
|
Experiment ID | 1005 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23463506
|
Organism | Homo sapiens |
Experiment description | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. |
Authors | Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartÃS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó |
Journal name |
J Biol Chem.
|
Publication year | 2013 |
Sample | T cells |
Sample name | T lymphoblasts - exosomes pulldown with EWI-2 as a bait |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV130110: EV-METRIC:22%
|
|
|
136
|
Experiment ID | 1008 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23463506
|
Organism | Homo sapiens |
Experiment description | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. |
Authors | Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartÃS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó |
Journal name |
J Biol Chem.
|
Publication year | 2013 |
Sample | T cells |
Sample name | T lymphoblasts |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130110: EV-METRIC:22%
|
|
|
137
|
Experiment ID | 538 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23844026
|
Organism | Homo sapiens |
Experiment description | Characterization of human thymic exosomes. |
Authors | Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Thymus |
Sample name | Normal-Thymus |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130018: EV-METRIC:63%
|
|
|
138
|
Experiment ID | 909 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
|
PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Transitional carcinoma cells |
Sample name | T24 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
|
|
|
139
|
Experiment ID | 680 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
140
|
Experiment ID | 681 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
141
|
Experiment ID | 682 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
142
|
Experiment ID | 683 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
143
|
Experiment ID | 684 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
144
|
Experiment ID | 685 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
145
|
Experiment ID | 13 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
15326289
|
Organism | Homo sapiens |
Experiment description | Identification and proteomic profiling of exosomes in human urine. |
Authors | Pisitkun T, Shen RF, Knepper MA |
Journal name |
PNAS
|
Publication year | 2004 |
Sample | Urine |
Sample name | Urine - Normal |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LCQ DECA XP] Western blotting |
EV-TRACK |
-
|
|
|
146
|
Experiment ID | 63 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
19056867
|
Organism | Homo sapiens |
Experiment description | Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Authors | Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
Journal name |
JASN
|
Publication year | 2009 |
Sample | Urine |
Sample name | Urine - Normal |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting |
EV-TRACK |
-
|
|
|
147
|
Experiment ID | 382 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
148
|
Experiment ID | 383 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
149
|
Experiment ID | 390 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane particles |
Identification method | Mass spectrometry
|
PubMed ID |
19158352
|
Organism | Homo sapiens |
Experiment description | Characterization of PKD protein-positive exosome-like vesicles. |
Authors | Hogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ. |
Journal name |
J Am Soc Nephrol
|
Publication year | 2009 |
Sample | Urine |
Sample name | Patients of autosomal recessive polycystic kidney disease-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
150
|
Experiment ID | 429 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
151
|
Experiment ID | 430 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of basement membrane nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
152
|
Experiment ID | 431 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of early IgA nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
153
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
|
|
154
|
Experiment ID | 444 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22418980
|
Organism | Homo sapiens |
Experiment description | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors | Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal_high density-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120083: EV-METRIC:22%
|
|
|
155
|
Experiment ID | 445 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22418980
|
Organism | Homo sapiens |
Experiment description | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors | Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal_low density-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120083: EV-METRIC:22%
|
|
|
156
|
Experiment ID | 478 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
157
|
Experiment ID | 479 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of hernia-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
158
|
Experiment ID | 498 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23376485
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. |
Authors | Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130051: EV-METRIC:38%
|
|
|
159
|
Experiment ID | 507 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23511837
|
Organism | Homo sapiens |
Experiment description | Differential protein profiling of renal cell carcinoma urinary exosomes. |
Authors | Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. |
Journal name |
Mol Biosyst
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130016: EV-METRIC:44%
|
|
|
160
|
Experiment ID | 508 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23511837
|
Organism | Homo sapiens |
Experiment description | Differential protein profiling of renal cell carcinoma urinary exosomes. |
Authors | Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. |
Journal name |
Mol Biosyst
|
Publication year | 2013 |
Sample | Urine |
Sample name | Renal cell carcinoma patient-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130016: EV-METRIC:44%
|
|
|
161
|
Experiment ID | 512 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Low-grade prostate cancer patient-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|
162
|
Experiment ID | 513 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|
163
|
Experiment ID | 540 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23886663
|
Organism | Homo sapiens |
Experiment description | LRRK2 Secretion in Exosomes is Regulated by 14-3-3. |
Authors | Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, Standaert DG, Kojima K, Mobley JA, West AB. |
Journal name |
Hum Mol Genet
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130075: EV-METRIC:11%, 11%, 33%
|
|
|
164
|
Experiment ID | 725 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25471207
|
Organism | Homo sapiens |
Experiment description | Intraluminal proteome and peptidome of human urinary extracellular vesicles. |
Authors | Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. |
Journal name |
Proteomics Clin Appl.
|
Publication year | 2015 |
Sample | Urine |
Sample name | Normal crude urine- Trypsinized |
Isolation/purification methods | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140189: EV-METRIC:25%
|
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165
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Experiment ID | 751 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
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PubMed ID |
29988836
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Organism | Homo sapiens |
Experiment description | Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine |
Authors | Oeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I. |
Journal name |
J Extracell Vesicles
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Publication year | 2018 |
Sample | Urine |
Sample name | Urine - Fraction 8 and 9 pooled |
Isolation/purification methods | Filtration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170025: EV-METRIC:62%
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166
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Experiment ID | 936 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - healthy volenteer 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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167
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Experiment ID | 937 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - healthy volenteer 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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168
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Experiment ID | 941 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 1 (Stage pT3a) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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169
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Experiment ID | 942 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 2 (Stage pT3a) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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170
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Experiment ID | 943 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 3 (Stage pT2b) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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171
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Experiment ID | 944 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 4 (Stage pT2a) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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172
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Experiment ID | 945 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 5 (Stage pT1) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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173
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Experiment ID | 946 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Western blotting
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urine |
Sample name | Urine - bladder cancer patient 6 (Stage pT1) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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174
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Experiment ID | 906 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
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PubMed ID |
29207636
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Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
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Publication year | 2017 |
Sample | Urothelial cells |
Sample name | SVHUC |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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175
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Experiment ID | 931 |
Identified molecule | protein
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Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
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PubMed ID |
29207636
|
Organism | Homo sapiens |
Experiment description | Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. |
Authors | Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. |
Journal name |
Oncotarget
|
Publication year | 2017 |
Sample | Urothelial cells |
Sample name | SVHUC |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170042: EV-METRIC:22%, 22%, 22%, 14%
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