Gene description for APCS
Gene name amyloid P component, serum
Gene symbol APCS
Other names/aliases PTX2
SAP
Species Homo sapiens
 Database cross references - APCS
Vesiclepedia VP_325
ExoCarta ExoCarta_325
Entrez Gene 325
HGNC 584
MIM 104770
 APCS identified in extracellular vesicles derived from the following tissue/cell type
Ascites [Microvesicles]      More >>> 21630462   
Ascites [Microvesicles]      More >>> 21630462   
Ascites [Microvesicles]      More >>> 21630462   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Breast milk [Extracellular vesicles]      More >>> 27601599   
Carotid atherosclerotic plaques [Microparticles]      More >>> 20031610   
Carotid atherosclerotic plaques [Microparticles]      More >>> 20031610   
Epididymal fluid [Prostasomes]      More >>> 18482993   
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles]      More >>> 23585444   
Neutrophils [Microparticles]      More >>> 23660474   
Neutrophils [Microparticles]      More >>> 23660474   
Plasma [Exosomes]      More >>> 24115447   
Plasma [Membrane vesicles/Microparticles]      More >>> 20156641   
Plasma [Microparticles]      More >>> 22329422   
Plasma [Microparticles]      More >>> 23056467   
Plasma [Exosomes]      More >>> 22046311   
Plasma [Extracellular vesicles]      More >>> 26154623   
Plasma [Extracellular vesicles]      More >>> 26154623   
Plasma [Extracellular vesicles]      More >>> 26154623   
Platelets [Microparticles]      More >>> 19806257   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Red blood cells [Microvesicles/Nanovesicles]      More >>> 18346024   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Umblical cord mesenchymal stem cells [Microvesicles]      More >>> 29148239   
Urine [Exosomes]      More >>> 15326289   
Urine [Exosomes]      More >>> 19056867   
Urine [Microparticles]      More >>> 18373357   
Urine [Microparticles]      More >>> 18373357   
Urine [Exosomes/Membrane vesicles]      More >>> 22106071   
Urine [Exosomes]      More >>> 22418980   
Urine [Exosomes]      More >>> 22418980   
Urine [Exosomes/Membrane vesicles]      More >>> 23082778   
Urine [Exosomes/Membrane vesicles]      More >>> 23082778   
Urine [Exosomes/Membrane vesicles]      More >>> 23376485   
Urine [Exosomes/Nanovesicles]      More >>> 23511837   
Urine [Exosomes/Nanovesicles]      More >>> 23511837   
Urine [Exosomes/Microvesicles]      More >>> 23533145   
Urine [Exosomes/Microvesicles]      More >>> 23533145   
Urine [Exosomes]      More >>> 25471207   
 Experiment description of studies that identified APCS in extracellular vesicles
1
Experiment ID157
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 1
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
2
Experiment ID158
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 2
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
3
Experiment ID159
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [LTQ]
PubMed ID 21630462   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of microvesicles derived from human colorectal cancer ascites
AuthorsChoi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS
Journal name Proteomics
Publication year2011
SampleAscites
Sample nameMalignant ascites - Colorectal cancer patient 3
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
OptiPrep density gradient
Flotation density1.09 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK EV110017: EV-METRIC:38%
4
Experiment ID574
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components
AuthorsVan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name MCP
Publication year2016
SampleBreast milk
Sample nameBreast milk - normal
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
5
Experiment ID951
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
6
Experiment ID952
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - D3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
7
Experiment ID957
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 27601599   
OrganismHomo sapiens
Experiment descriptionComprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.
Authorsvan Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH
Journal name Mol Cell Proteomics
Publication year2016
SampleBreast milk
Sample nameMilk - derived EVs - pooled
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.12-1.18 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV160000: EV-METRIC:50%
8
Experiment ID408
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Proton Nucelar Magnetic Resonance Spectrometry
PubMed ID 20031610   
OrganismHomo sapiens
Experiment descriptionProteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
AuthorsMayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM.
Journal name Circ Cardiovasc Genet
Publication year2009
SampleCarotid atherosclerotic plaques
Sample nameNormal-Carotid atherosclerotic plaque
Isolation/purification methods-
Flotation density-
Molecules identified in the studyMetabolites
Methods used in the studyProton Nucelar Magnetic Resonance Spectrometry
EV-TRACK -
9
Experiment ID409
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 20031610   
OrganismHomo sapiens
Experiment descriptionProteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
AuthorsMayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM.
Journal name Circ Cardiovasc Genet
Publication year2009
SampleCarotid atherosclerotic plaques
Sample namePatients of carotid atherosclerosis-Carotid atherosclerotic plaque
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
10
Experiment ID384
Identified moleculeprotein
Extracellular vesicle typeProstasomes
Identification method Mass spectrometry
PubMed ID 18482993   
OrganismHomo sapiens
Experiment descriptionProtein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.
AuthorsThimon V, Frenette G, Saez F, Thabet M, Sullivan R.
Journal name Hum Reprod
Publication year2008
SampleEpididymal fluid
Sample nameNormal-Epididymal fluid
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
11
Experiment ID519
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles/Ectosomes/Microparticles
Identification method Mass spectrometry
PubMed ID 23585444   
OrganismHomo sapiens
Experiment descriptionIdentification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
AuthorsPark JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP.
Journal name Proteomics
Publication year2013
SampleMalignant pleural effusions
Sample nameNon-small cell lung cancer patient-Lung cancer pleural effusion
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130049: EV-METRIC:38%
12
Experiment ID526
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23660474   
OrganismHomo sapiens
Experiment descriptionHeterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
AuthorsDalli J, Montero Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M.
Journal name Mol Cell Proteomics
Publication year2013
SampleNeutrophils
Sample nameStimulated in fluid phase-Neutrophil
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
13
Experiment ID527
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23660474   
OrganismHomo sapiens
Experiment descriptionHeterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
AuthorsDalli J, Montero Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M.
Journal name Mol Cell Proteomics
Publication year2013
SampleNeutrophils
Sample nameStimulated in immobile phase-Neutrophil
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
14
Experiment ID353
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry [Orbitrap Velos]
PubMed ID 24115447   
OrganismHomo sapiens
Experiment descriptionComparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma
AuthorsMathivanan,S.
Journal name Proteomics
Publication year2013
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [Orbitrap Velos]
Western blotting
EV-TRACK EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%
15
Experiment ID412
Identified moleculeprotein
Extracellular vesicle typeMembrane vesicles/Microparticles
Identification method Mass spectrometry
PubMed ID 20156641   
OrganismHomo sapiens
Experiment descriptionProteomics of microparticles after deep venous thrombosis.
AuthorsRamacciotti E, Hawley AE, Wrobleski SK, Myers DD Jr, Strahler JR, Andrews PC, Guire KE, Henke PK, Wakefield TW.
Journal name Thromb Res
Publication year2010
SamplePlasma
Sample nameNormal donors and patients of deep venous thrombosis-Plasma
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
16
Experiment ID443
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 22329422   
OrganismHomo sapiens
Experiment descriptionQuantitative proteome profiling of normal human circulating microparticles.
AuthorsØstergaard O, Nielsen CT, Iversen LV, Jacobsen S, Tanassi JT, Heegaard NH.
Journal name J Proteome Res
Publication year2012
SamplePlasma
Sample nameNormal-Platelet-poor plasma
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
17
Experiment ID473
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 23056467   
OrganismHomo sapiens
Experiment descriptionCause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.
AuthorsAl Kaabi A, Traupe T, Stutz M, Buchs N, Heller M.
Journal name PLoS One
Publication year2012
SamplePlasma
Sample namePatients of external counterpulsation therapy-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
18
Experiment ID863
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22046311   
OrganismMus musculus
Experiment descriptionExosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
AuthorsMartin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA.
Journal name PLoS One
Publication year2011
SamplePlasma
Sample namePeripheral blood plasma - P. yoelii 17X infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
Mass spectrometry
EV-TRACK EV110102: EV-METRIC:25%, 25%
19
Experiment ID1223
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 1
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%
20
Experiment ID1224
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 2
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%
21
Experiment ID1225
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 3
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%
22
Experiment ID406
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 19806257   
OrganismHomo sapiens
Experiment descriptionProteomic and functional characterisation of platelet microparticle size classes.
AuthorsDean WL, Lee MJ, Cummins TD, Schultz DJ, Powell DW.
Journal name Thromb Haemost
Publication year2009
SamplePlatelets
Sample nameNormal donors-Platelets
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
23
Experiment ID376
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 21-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
24
Experiment ID377
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 3-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
25
Experiment ID378
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameMicrovesicle, Storage day 42-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
26
Experiment ID379
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 21-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
27
Experiment ID380
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 3-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
28
Experiment ID381
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles/Nanovesicles
Identification method Mass spectrometry
PubMed ID 18346024   
OrganismHomo sapiens
Experiment descriptionThe proteome of red cell membranes and vesicles during storage in blood bank conditions.
AuthorsBosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ.
Journal name Transfusion
Publication year2008
SampleRed blood cells
Sample nameNanovesicle, Storage day 42-Red blood cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
29
Experiment ID680
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
30
Experiment ID681
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
31
Experiment ID682
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample namePreterm newborns- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
32
Experiment ID683
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
33
Experiment ID684
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
34
Experiment ID685
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry
PubMed ID 29148239   
OrganismHomo sapiens
Experiment descriptionMetabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.
AuthorsBruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I.
Journal name Proteomics Clin Appl
Publication year2018
SampleUmblical cord mesenchymal stem cells
Sample nameTerm infants- replicate 3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sonication
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
35
Experiment ID13
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 15326289   
OrganismHomo sapiens
Experiment descriptionIdentification and proteomic profiling of exosomes in human urine.
AuthorsPisitkun T, Shen RF, Knepper MA
Journal name PNAS
Publication year2004
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsUltracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LCQ DECA XP]
Western blotting
EV-TRACK -
36
Experiment ID63
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 19056867   
OrganismHomo sapiens
Experiment descriptionLarge-scale proteomics and phosphoproteomics of urinary exosomes.
AuthorsGonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year2009
SampleUrine
Sample nameUrine - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
EV-TRACK -
37
Experiment ID382
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 18373357   
OrganismHomo sapiens
Experiment descriptionIsolation and identification of potential urinary microparticle biomarkers of bladder cancer.
AuthorsSmalley DM, Sheman NE, Nelson K, Theodorescu D.
Journal name J Proteome Res
Publication year2008
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
38
Experiment ID383
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
Identification method Mass spectrometry
PubMed ID 18373357   
OrganismHomo sapiens
Experiment descriptionIsolation and identification of potential urinary microparticle biomarkers of bladder cancer.
AuthorsSmalley DM, Sheman NE, Nelson K, Theodorescu D.
Journal name J Proteome Res
Publication year2008
SampleUrine
Sample namePatients of bladder cancer-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -
39
Experiment ID437
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 22106071   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
AuthorsWang Z, Hill S, Luther JM, Hachey DL, Schey KL.
Journal name Proteomics
Publication year2012
SampleUrine
Sample nameNormal donors-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120168: EV-METRIC:14%
40
Experiment ID444
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22418980   
OrganismHomo sapiens
Experiment descriptionA multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
AuthorsRaj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year2012
SampleUrine
Sample nameNormal_high density-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120083: EV-METRIC:22%
41
Experiment ID445
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22418980   
OrganismHomo sapiens
Experiment descriptionA multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
AuthorsRaj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year2012
SampleUrine
Sample nameNormal_low density-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120083: EV-METRIC:22%
42
Experiment ID478
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23082778   
OrganismHomo sapiens
Experiment descriptionComparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.
AuthorsChen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT.
Journal name J Proteome Res
Publication year2012
SampleUrine
Sample namePatients of bladder cancer-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120030: EV-METRIC:33%
43
Experiment ID479
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23082778   
OrganismHomo sapiens
Experiment descriptionComparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.
AuthorsChen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT.
Journal name J Proteome Res
Publication year2012
SampleUrine
Sample namePatients of hernia-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120030: EV-METRIC:33%
44
Experiment ID498
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
Identification method Mass spectrometry
PubMed ID 23376485   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of podocyte exosome-enriched fraction from normal human urine.
AuthorsPrunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S.
Journal name J Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130051: EV-METRIC:38%
45
Experiment ID507
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameNormal-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%
46
Experiment ID508
Identified moleculeprotein
Extracellular vesicle typeExosomes/Nanovesicles
Identification method Mass spectrometry
PubMed ID 23511837   
OrganismHomo sapiens
Experiment descriptionDifferential protein profiling of renal cell carcinoma urinary exosomes.
AuthorsRaimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M.
Journal name Mol Biosyst
Publication year2013
SampleUrine
Sample nameRenal cell carcinoma patient-Urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130016: EV-METRIC:44%
47
Experiment ID512
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameLow-grade prostate cancer patient-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%
48
Experiment ID513
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
Identification method Mass spectrometry
PubMed ID 23533145   
OrganismHomo sapiens
Experiment descriptionIn-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
AuthorsPrincipe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR.
Journal name Proteomics
Publication year2013
SampleUrine
Sample nameNormal-Expressed prostatic secretions in urine
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130224: EV-METRIC:14%
49
Experiment ID725
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 25471207   
OrganismHomo sapiens
Experiment descriptionIntraluminal proteome and peptidome of human urinary extracellular vesicles.
AuthorsLiu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H.
Journal name Proteomics Clin Appl.
Publication year2015
SampleUrine
Sample nameNormal crude urine- Trypsinized
Isolation/purification methodsDifferential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140189: EV-METRIC:25%