Gene description for Rac1
Gene name	CG2248 gene product from transcript CG2248-RA
Gene symbol	Rac1
Other names/aliases	2248 CG2248 D-Rac D-Rac 1 D-Rac1 DRac DRac1 DRacA Dm Rac1 DmRAC DmRAC1 DmelCG2248 Dmrac1 Drac Drac1 Drac1a DracA GTPase Rac1 RAC1 Rac Rac GTPase Rac-1 RacA dRac dRac1 rac rac1
Species	Drosophila melanogaster
Database cross references - Rac1
Vesiclepedia	VP_38146
ExoCarta	ExoCarta_38146
Entrez Gene	38146
Rac1 identified in extracellular vesicles derived from the following tissue/cell type
Drosophila S2 cells [Exosomes]      More >>>	22437826
Drosophila wing imaginal Disc [Extracellular vesicles]      More >>>	25471885
Hematocytes [Microvesicles]      More >>>	21901833
Hematocytes [Microvesicles]      More >>>	21901833
Experiment description of studies that identified Rac1 in extracellular vesicles
1 Experiment ID 1278 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 22437826    Organism Drosophila melanogaster Experiment description Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Authors Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. Journal name J Biol Chem Publication year 2012 Sample Drosophila S2 cells Sample name S2 cells Isolation/purification methods Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120033: EV-METRIC:33%
2 Experiment ID 979 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 25471885    Organism Drosophila melanogaster Experiment description The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Authors Matusek T, Wendler F, PolèS, Pizette S, D'Angelo G, Füer M, Thénd PP. Journal name Nature Publication year 2014 Sample Drosophila wing imaginal Disc Sample name C18 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140287: EV-METRIC:11%, 22%
3 Experiment ID 161 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [HCT ETD II iontrap] PubMed ID 21901833    Organism Drosophila melanogaster Experiment description Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Authors Koppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T Journal name Proteomics Publication year 2011 Sample Hematocytes Sample name Kc167 Isolation/purification methods Differential centrifugation Sucrose density gradient Ultracentrifugation Flotation density - Molecules identified in the study Protein PTM Ubiquitination Methods used in the study Western blotting Mass spectrometry [HCT ETD II iontrap] EV-TRACK EV110006: EV-METRIC:63%
4 Experiment ID 162 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry [HCT ETD II iontrap] PubMed ID 21901833    Organism Drosophila melanogaster Experiment description Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Authors Koppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T Journal name Proteomics Publication year 2011 Sample Hematocytes Sample name S2 Isolation/purification methods Differential centrifugation Sucrose density gradient Ultracentrifugation Flotation density - Molecules identified in the study Protein PTM Ubiquitination Methods used in the study Western blotting Mass spectrometry [HCT ETD II iontrap] EV-TRACK EV110006: EV-METRIC:63%