Gene description for Rac1 |
Gene name |
CG2248 gene product from transcript CG2248-RA |
Gene symbol |
Rac1 |
Other names/aliases |
2248 CG2248 D-Rac D-Rac 1 D-Rac1 DRac DRac1 DRacA Dm Rac1 DmRAC DmRAC1 DmelCG2248 Dmrac1 Drac Drac1 Drac1a DracA GTPase Rac1 RAC1 Rac Rac GTPase Rac-1 RacA dRac dRac1 rac rac1 |
Species |
Drosophila melanogaster |
Database cross references - Rac1 |
Vesiclepedia |
VP_38146 |
ExoCarta |
ExoCarta_38146 |
Entrez Gene |
38146 |
Rac1 identified in extracellular vesicles derived from the following tissue/cell type |
Drosophila S2 cells [Exosomes] More >>>
|
22437826
|
Drosophila wing imaginal Disc [Extracellular vesicles] More >>>
|
25471885
|
Hematocytes [Microvesicles] More >>>
|
21901833
|
Hematocytes [Microvesicles] More >>>
|
21901833
|
Experiment description of studies that identified Rac1 in extracellular vesicles |
1
|
Experiment ID | 1278 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22437826
|
Organism | Drosophila melanogaster |
Experiment description | Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. |
Authors | Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. |
Journal name |
J Biol Chem
|
Publication year | 2012 |
Sample | Drosophila S2 cells |
Sample name | S2 cells |
Isolation/purification methods | Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120033: EV-METRIC:33%
|
|
|
2
|
Experiment ID | 979 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
25471885
|
Organism | Drosophila melanogaster |
Experiment description | The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. |
Authors | Matusek T, Wendler F, PolèS, Pizette S, D'Angelo G, Füer M, Thénd PP. |
Journal name |
Nature
|
Publication year | 2014 |
Sample | Drosophila wing imaginal Disc |
Sample name | C18 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140287: EV-METRIC:11%, 22%
|
|
|
3
|
Experiment ID | 161 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [HCT ETD II iontrap]
|
PubMed ID |
21901833
|
Organism | Drosophila melanogaster |
Experiment description | Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells |
Authors | Koppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Hematocytes |
Sample name | Kc167 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein PTM Ubiquitination |
Methods used in the study | Western blotting Mass spectrometry [HCT ETD II iontrap] |
EV-TRACK |
EV110006: EV-METRIC:63%
|
|
|
4
|
Experiment ID | 162 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [HCT ETD II iontrap]
|
PubMed ID |
21901833
|
Organism | Drosophila melanogaster |
Experiment description | Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells |
Authors | Koppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Hematocytes |
Sample name | S2 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein PTM Ubiquitination |
Methods used in the study | Western blotting Mass spectrometry [HCT ETD II iontrap] |
EV-TRACK |
EV110006: EV-METRIC:63%
|
|
|