Gene description for Rac1
Gene name CG2248 gene product from transcript CG2248-RA
Gene symbol Rac1
Other names/aliases 2248
CG2248
D-Rac
D-Rac 1
D-Rac1
DRac
DRac1
DRacA
Dm Rac1
DmRAC
DmRAC1
DmelCG2248
Dmrac1
Drac
Drac1
Drac1a
DracA
GTPase Rac1
RAC1
Rac
Rac GTPase
Rac-1
RacA
dRac
dRac1
rac
rac1
Species Drosophila melanogaster
 Database cross references - Rac1
Vesiclepedia VP_38146
ExoCarta ExoCarta_38146
Entrez Gene 38146
 Rac1 identified in extracellular vesicles derived from the following tissue/cell type
Drosophila S2 cells [Exosomes]      More >>> 22437826   
Drosophila wing imaginal Disc [Extracellular vesicles]      More >>> 25471885   
Hematocytes [Microvesicles]      More >>> 21901833   
Hematocytes [Microvesicles]      More >>> 21901833   
 Experiment description of studies that identified Rac1 in extracellular vesicles
1
Experiment ID1278
Identified moleculeprotein
Extracellular vesicle typeExosomes
Identification method Mass spectrometry
PubMed ID 22437826   
OrganismDrosophila melanogaster
Experiment descriptionMechanism of evenness interrupted (Evi)-exosome release at synaptic boutons.
AuthorsKoles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V.
Journal name J Biol Chem
Publication year2012
SampleDrosophila S2 cells
Sample nameS2 cells
Isolation/purification methodsUltracentrifugation
Density gradient centrifugation
Flotation density1.15-1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120033: EV-METRIC:33%
2
Experiment ID979
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
Identification method Mass spectrometry
PubMed ID 25471885   
OrganismDrosophila melanogaster
Experiment descriptionThe ESCRT machinery regulates the secretion and long-range activity of Hedgehog.
AuthorsMatusek T, Wendler F, PolèS, Pizette S, D'Angelo G, Füer M, Thénd PP.
Journal name Nature
Publication year2014
SampleDrosophila wing imaginal Disc
Sample nameC18
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140287: EV-METRIC:11%, 22%
3
Experiment ID161
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [HCT ETD II iontrap]
PubMed ID 21901833   
OrganismDrosophila melanogaster
Experiment descriptionProteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells
AuthorsKoppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T
Journal name Proteomics
Publication year2011
SampleHematocytes
Sample nameKc167
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
PTM Ubiquitination
Methods used in the studyWestern blotting
Mass spectrometry [HCT ETD II iontrap]
EV-TRACK EV110006: EV-METRIC:63%
4
Experiment ID162
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
Identification method Mass spectrometry [HCT ETD II iontrap]
PubMed ID 21901833   
OrganismDrosophila melanogaster
Experiment descriptionProteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells
AuthorsKoppen T, Weckmann A, MüS, Staubach S, Bloch W, Dohmen RJ, Schwientek T
Journal name Proteomics
Publication year2011
SampleHematocytes
Sample nameS2
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
PTM Ubiquitination
Methods used in the studyWestern blotting
Mass spectrometry [HCT ETD II iontrap]
EV-TRACK EV110006: EV-METRIC:63%