Gene description for NAP1L4
Gene name	nucleosome assembly protein 1-like 4
Gene symbol	NAP1L4
Other names/aliases	NAP1L4b NAP2 NAP2L hNAP2
Species	Homo sapiens
Database cross references - NAP1L4
Vesiclepedia	VP_4676
ExoCarta	ExoCarta_4676
Entrez Gene	4676
HGNC	7640
MIM	601651
NAP1L4 identified in extracellular vesicles derived from the following tissue/cell type
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Brain cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Chronic lymphocytic leukemia cells [Exosomes]      More >>>	26100252
Colorectal cancer cells [Microvesicles]      More >>>	19930720
Colorectal cancer cells [Exosomes]      More >>>	22285593
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Endothelial cells [Microparticles]      More >>>	18563738
Endothelial cells [Microparticles]      More >>>	18563738
Endothelial cells [Microparticles]      More >>>	18563738
Endothelial cells [Exosomes/Extracellular vesicles]      More >>>	24009886
Glioblastoma cells [Microvesicles]      More >>>	19011622
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Kidney cancer cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Leukemia cells [Exosomes]      More >>>	24939845
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Lung cancer cells [Extracellular vesicles]      More >>>	24946052
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Neonatal myoblast cells [Microvesicles/Nanovesicles]      More >>>	23000592
Neuroblastoma cells [Exosomes]      More >>>	25053844
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Plasma [Microparticles]      More >>>	23056467
Platelets [Microparticles]      More >>>	23601281
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
T cells [Microparticles]      More >>>	16342139
T cells [Apoptotic bodies]      More >>>	28811610
T cells [Exosomes]      More >>>	23463506
T cells [Exosomes]      More >>>	23463506
Thymus [Exosomes]      More >>>	23844026
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Urine [Exosomes/Membrane vesicles]      More >>>	22106071
Experiment description of studies that identified NAP1L4 in extracellular vesicles
1 Experiment ID 1059 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1062 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1064 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 3 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 79 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
5 Experiment ID 81 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
6 Experiment ID 534 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name EBV- and KSHV-infected B cells (JSC-1, BC1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
7 Experiment ID 535 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name EBV-infected B cells (#1, HLJ, IM9, CP) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
8 Experiment ID 536 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name KSHV-infected B cell (JC, BC3, BCP1, BCBL1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
9 Experiment ID 537 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name Normal B cells (BJAB) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
10 Experiment ID 905 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
11 Experiment ID 930 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
12 Experiment ID 581 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SF268 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
13 Experiment ID 584 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SNB-19 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
14 Experiment ID 585 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Brain cancer cells Sample name SNB-75 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
15 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
16 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
17 Experiment ID 902 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name MEC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS Western blotting EV-TRACK EV150015: EV-METRIC:22%, 44%
18 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina] EV-TRACK -
19 Experiment ID 348 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Orbitrap] PubMed ID 22285593    Organism Homo sapiens Experiment description Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Authors Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ Journal name Methods Publication year 2012 Sample Colorectal cancer cells Sample name LIM1863 - EpCAM immunoaffinity Isolation/purification methods Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting EV-TRACK EV120024: EV-METRIC:25%, 33%, 50%
20 Experiment ID 517 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
21 Experiment ID 518 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
22 Experiment ID 549 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
23 Experiment ID 550 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
24 Experiment ID 587 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name Colo205 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
25 Experiment ID 588 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HCC 2998 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
26 Experiment ID 589 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HCT-116 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
27 Experiment ID 696 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- insulin induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
28 Experiment ID 697 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- non-induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
29 Experiment ID 1049 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215 - NI Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
30 Experiment ID 1050 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name lim1215 - II Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
31 Experiment ID 385 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
32 Experiment ID 386 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by PAI-1-Endothelial cell (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
33 Experiment ID 387 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by TNF-alpha-Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
34 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%
35 Experiment ID 203 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray PubMed ID 19011622    Organism Homo sapiens Experiment description Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Authors Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO Journal name Nat Cell Biol Publication year 2008 Sample Glioblastoma cells Sample name Glioblastoma cells Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA mRNA Methods used in the study RT-PCR Antibody array Microarray EV-TRACK -
36 Experiment ID 596 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name ACHN Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
37 Experiment ID 597 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Kidney cancer cells Sample name CAKI Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
38 Experiment ID 607 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name SR Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
39 Experiment ID 1248 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24939845    Organism Homo sapiens Experiment description Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Authors Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. Journal name J Biol Chem. Publication year 2014 Sample Leukemia cells Sample name CEM - uninfected Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140028: EV-METRIC:33%
40 Experiment ID 609 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name EKVX Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
41 Experiment ID 611 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name HOP-92 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
42 Experiment ID 612 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H226 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
43 Experiment ID 615 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H460 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
44 Experiment ID 616 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name NCI-H522 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
45 Experiment ID 889 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
46 Experiment ID 890 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
47 Experiment ID 891 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
48 Experiment ID 893 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
49 Experiment ID 894 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
50 Experiment ID 895 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 24946052    Organism Homo sapiens Experiment description Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Authors Choi DY, You S, Jung JH, Lee JC, Rho JK, Lee KY, Freeman MR, Kim KP, Kim J. Journal name Proteomics Publication year 2014 Sample Lung cancer cells Sample name PC9 - gefitinib-resistant - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density Not provided Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140109: EV-METRIC:25%
51 Experiment ID 620 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MDA-MB-435 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
52 Experiment ID 467 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_exosome-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
53 Experiment ID 468 Identified molecule protein Extracellular vesicle type Microvesicles/Nanovesicles Identification method Mass spectrometry PubMed ID 23000592    Organism Homo sapiens Experiment description In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Authors Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. Journal name J Proteomics Publication year 2012 Sample Neonatal myoblast cells Sample name Patient of developmental heart defect_microparticle-Neonatal myoblast cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
54 Experiment ID 903 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25053844    Organism Homo sapiens Experiment description Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Authors Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ. Journal name Nucleic Acids Res Publication year 2014 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140076: EV-METRIC:38%
55 Experiment ID 628 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-4 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
56 Experiment ID 632 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name NCI-ADR-RES Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
57 Experiment ID 992 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
58 Experiment ID 993 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR433 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
59 Experiment ID 994 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR5 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
60 Experiment ID 995 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name SKOV3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
61 Experiment ID 473 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 23056467    Organism Homo sapiens Experiment description Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Authors Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. Journal name PLoS One Publication year 2012 Sample Plasma Sample name Patients of external counterpulsation therapy-Blood Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
62 Experiment ID 520 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry PubMed ID 23601281    Organism Homo sapiens Experiment description Proteomic characterization of human platelet-derived microparticles. Authors Capriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A. Journal name Anal Chim Acta Publication year 2013 Sample Platelets Sample name Platelets purifird from blood Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
63 Experiment ID 851 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
64 Experiment ID 852 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
65 Experiment ID 853 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
66 Experiment ID 1195 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget. Publication year 2016 Sample Prostate cancer cells Sample name DUCaP, EtOH Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
67 Experiment ID 307 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF] PubMed ID 16342139    Organism Homo sapiens Experiment description Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization Authors Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L Journal name Proteomics Publication year 2006 Sample T cells Sample name CEM T cell - ActD activation Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] EV-TRACK -
68 Experiment ID 715 Identified molecule protein Extracellular vesicle type Apoptotic bodies Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Apoptotic Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
69 Experiment ID 1005 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts - exosomes pulldown with EWI-2 as a bait Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130110: EV-METRIC:22%
70 Experiment ID 1008 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130110: EV-METRIC:22%
71 Experiment ID 538 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23844026    Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130018: EV-METRIC:63%
72 Experiment ID 680 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
73 Experiment ID 681 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
74 Experiment ID 682 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
75 Experiment ID 683 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
76 Experiment ID 684 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
77 Experiment ID 685 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
78 Experiment ID 437 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 22106071    Organism Homo sapiens Experiment description Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Authors Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. Journal name Proteomics Publication year 2012 Sample Urine Sample name Normal donors-Urine Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120168: EV-METRIC:14%