Gene description for NME2 |
Gene name |
NME/NM23 nucleoside diphosphate kinase 2 |
Gene symbol |
NME2 |
Other names/aliases |
NDKB NDPK-B NDPKB NM23-H2 NM23B PUF |
Species |
Homo sapiens |
Database cross references - NME2 |
Vesiclepedia |
VP_4831 |
ExoCarta |
ExoCarta_4831 |
Entrez Gene |
4831 |
HGNC |
7850 |
MIM |
156491 |
NME2 identified in extracellular vesicles derived from the following tissue/cell type |
Ascites [Microvesicles] More >>>
|
21630462
|
Ascites [Microvesicles] More >>>
|
21630462
|
Ascites [Microvesicles] More >>>
|
21630462
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23983189
|
B cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23983189
|
Bladder cancer cells [Exosomes] More >>>
|
20224111
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Colorectal cancer cells [Exosomes] More >>>
|
17956143
|
Colorectal cancer cells [Microvesicles] More >>>
|
19930720
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Endothelial cells [Exosomes/Extracellular vesicles] More >>>
|
24009886
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Glioblastoma cells [Microvesicles] More >>>
|
19011622
|
Glioblastoma cells [Microvesicles] More >>>
|
23807490
|
Hepatocytes [Microvesicles] More >>>
|
19650833
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles] More >>>
|
23585444
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Mesenchymal stem cells [Exosomes] More >>>
|
Unpublished / Not applicable
|
Mesenchymal stem cells [Microvesicles] More >>>
|
19389847
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Monocytes [Microparticles] More >>>
|
19548909
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Placenta [Exosomes] More >>>
|
25157233
|
Plasma [Microparticles] More >>>
|
22669077
|
Platelets [Microparticles] More >>>
|
23601281
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22030351
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Extracellular vesicles] More >>>
|
28881726
|
Prostate cancer cells [Exosomes] More >>>
|
25844599
|
Retinal pigment epithelial cells [Exosomes] More >>>
|
24400796
|
Saliva [Exosomes] More >>>
|
19199708
|
Seminal plasma [Prostasomes] More >>>
|
23707955
|
T cells [Microparticles] More >>>
|
16342139
|
T cells [Microparticles] More >>>
|
16342139
|
T cells [Microvesicles] More >>>
|
28811610
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Urine [Exosomes] More >>>
|
22418980
|
Urine [Exosomes] More >>>
|
22418980
|
Urine [Exosomes/Membrane vesicles] More >>>
|
23082778
|
Urine [Exosomes/Membrane vesicles] More >>>
|
23082778
|
Urine [Exosomes/Microvesicles] More >>>
|
23533145
|
Urine [Exosomes/Microvesicles] More >>>
|
23533145
|
Experiment description of studies that identified NME2 in extracellular vesicles |
1
|
Experiment ID | 157 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 1 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
2
|
Experiment ID | 158 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 2 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
3
|
Experiment ID | 159 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
21630462
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer ascites |
Authors | Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP, Gho YS |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Ascites |
Sample name | Malignant ascites - Colorectal cancer patient 3 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
EV110017: EV-METRIC:38%
|
|
|
4
|
Experiment ID | 1059 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1060 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1061 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373 - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1062 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 1 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1063 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 2 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1064 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 79 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
11
|
Experiment ID | 80 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
12
|
Experiment ID | 81 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
13
|
Experiment ID | 545 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23983189
|
Organism | Homo sapiens |
Experiment description | Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. |
Authors | Harshman SW, Canella A, Ciarlariello PD, Rocci A, Agarwal K, Smith EM, Talabere T, Efebera YA, Hofmeister CC, Benson DM Jr, Paulaitis ME, Freitas MA, Pichiorri F. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | B cells |
Sample name | MM.1S |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130092: EV-METRIC:22%
|
|
|
14
|
Experiment ID | 546 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23983189
|
Organism | Homo sapiens |
Experiment description | Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. |
Authors | Harshman SW, Canella A, Ciarlariello PD, Rocci A, Agarwal K, Smith EM, Talabere T, Efebera YA, Hofmeister CC, Benson DM Jr, Paulaitis ME, Freitas MA, Pichiorri F. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | B cells |
Sample name | U266 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130092: EV-METRIC:22%
|
|
|
15
|
Experiment ID | 76 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20224111
|
Organism | Homo sapiens |
Experiment description | Proteomics analysis of bladder cancer exosomes. |
Authors | Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. |
Journal name |
MCP
|
Publication year | 2010 |
Sample | Bladder cancer cells |
Sample name | HT1376 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.10-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Western blotting FACS |
EV-TRACK |
EV100014: EV-METRIC:38%, 14%, 44%
|
|
|
16
|
Experiment ID | 585 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | SNB-75 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
17
|
Experiment ID | 586 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
19
|
Experiment ID | 577 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
20
|
Experiment ID | 579 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MDA-MB-468 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
21
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
22
|
Experiment ID | 950 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
23
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
24
|
Experiment ID | 952 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
25
|
Experiment ID | 954 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
26
|
Experiment ID | 955 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D6 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
27
|
Experiment ID | 956 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
28
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
29
|
Experiment ID | 1207 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 1 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
30
|
Experiment ID | 1208 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 2 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
31
|
Experiment ID | 1209 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 3 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
32
|
Experiment ID | 1210 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 4 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
33
|
Experiment ID | 1211 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 5 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
34
|
Experiment ID | 1212 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 1 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
35
|
Experiment ID | 1213 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 2 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
36
|
Experiment ID | 1214 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 3 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
37
|
Experiment ID | 901 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | JVM-3 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
38
|
Experiment ID | 902 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | MEC-1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry FACS Western blotting |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
39
|
Experiment ID | 20 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
17956143
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human colorectal cancer cells. |
Authors | Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS |
Journal name |
JPR
|
Publication year | 2007 |
Sample | Colorectal cancer cells |
Sample name | HT29 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density | 1.16 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting |
EV-TRACK |
-
|
|
|
40
|
Experiment ID | 303 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray [Illumina]
|
PubMed ID |
19930720
|
Organism | Homo sapiens |
Experiment description | Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells |
Authors | Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS |
Journal name |
BMC Genomics
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | Differential centrifugation Ultrafiltration OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein mRNA |
Methods used in the study | Western blotting RT-PCR Microarray [Illumina] |
EV-TRACK |
-
|
|
|
41
|
Experiment ID | 486 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
42
|
Experiment ID | 487 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
43
|
Experiment ID | 488 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Shed vesicles-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
44
|
Experiment ID | 517 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
45
|
Experiment ID | 518 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
46
|
Experiment ID | 587 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | Colo205 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
47
|
Experiment ID | 589 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | HCT-116 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
48
|
Experiment ID | 590 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | HCT-15 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
49
|
Experiment ID | 592 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | KM12 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
50
|
Experiment ID | 1050 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | lim1215 - II |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
51
|
Experiment ID | 925 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P150 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
52
|
Experiment ID | 927 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P450 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
53
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|
54
|
Experiment ID | 862 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 2 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
55
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
56
|
Experiment ID | 1274 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23807490
|
Organism | Homo sapiens |
Experiment description | Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. |
Authors | Li CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, Grau GE, Combes V, Bebawy M, Gong J, Brammah S, Buckland ME, Suter CM. |
Journal name |
RNA Biol.
|
Publication year | 2013 |
Sample | Glioblastoma cells |
Sample name | U251 cells |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray |
EV-TRACK |
EV130098: EV-METRIC:29%
|
|
|
57
|
Experiment ID | 405 |
Identified molecule | mRNA
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19650833
|
Organism | Homo sapiens |
Experiment description | Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. |
Authors | Herrera MB, Fonsato V, Gatti S, Deregibus MC, Sordi A, Cantarella D, Calogero R, Bussolati B, Tetta C, Camussi G. |
Journal name |
J Cell Mol Med
|
Publication year | 2010 |
Sample | Hepatocytes |
Sample name | Normal-Hepatocytes |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | mRNA |
Methods used in the study | Microarray |
EV-TRACK |
-
|
|
|
58
|
Experiment ID | 594 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | 786-O |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
59
|
Experiment ID | 596 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | ACHN |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
60
|
Experiment ID | 597 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | CAKI |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
61
|
Experiment ID | 600 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | TK-10 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
62
|
Experiment ID | 602 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | CCRF-CEM |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
63
|
Experiment ID | 604 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | K562 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
64
|
Experiment ID | 605 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | MOLT-4 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
65
|
Experiment ID | 607 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | SR |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
66
|
Experiment ID | 616 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H522 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
67
|
Experiment ID | 519 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Ectosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23585444
|
Organism | Homo sapiens |
Experiment description | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. |
Authors | Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Malignant pleural effusions |
Sample name | Non-small cell lung cancer patient-Lung cancer pleural effusion |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130049: EV-METRIC:38%
|
|
|
68
|
Experiment ID | 620 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | MDA-MB-435 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
69
|
Experiment ID | 621 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-2 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
70
|
Experiment ID | 622 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-28 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
71
|
Experiment ID | 623 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-5 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
72
|
Experiment ID | 126 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
Unpublished / Not applicable
|
Organism | Homo sapiens |
Experiment description | Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? |
Authors | Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim |
Journal name |
Mesenchymal Stem Cell Therapy
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | huES9.E1 |
Isolation/purification methods | HPLC |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Antibody array Mass spectrometry |
EV-TRACK |
-
|
|
|
73
|
Experiment ID | 394 |
Identified molecule | mRNA
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19389847
|
Organism | Homo sapiens |
Experiment description | Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. |
Authors | Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, Tetta C, Camussi G. |
Journal name |
J Am Soc Nephrol
|
Publication year | 2009 |
Sample | Mesenchymal stem cells |
Sample name | Normal-Mesenchymal stem cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | mRNA |
Methods used in the study | Microarray |
EV-TRACK |
-
|
|
|
74
|
Experiment ID | 401 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
75
|
Experiment ID | 402 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by IgG-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
76
|
Experiment ID | 403 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by LPS-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
77
|
Experiment ID | 404 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19548909
|
Organism | Homo sapiens |
Experiment description | Differential stimulation of monocytic cells results in distinct populations of microparticles. |
Authors | Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD. |
Journal name |
J Thromb Haemost
|
Publication year | 2009 |
Sample | Monocytes |
Sample name | Stimulated by P-selectin-Ig-Monocytes (THP-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
78
|
Experiment ID | 467 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_exosome-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
79
|
Experiment ID | 468 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_microparticle-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
80
|
Experiment ID | 630 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-8 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
81
|
Experiment ID | 631 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | SK-OV-3 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
82
|
Experiment ID | 992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
83
|
Experiment ID | 993 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR433 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
84
|
Experiment ID | 994 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
85
|
Experiment ID | 995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | SKOV3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
86
|
Experiment ID | 739 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25157233
|
Organism | Homo sapiens |
Experiment description | Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. |
Authors | Salomon C, Yee S, Scholz-Romero K, Kobayashi M, Vaswani K, Kvaskoff D, Illanes SE, Mitchell MD, Rice GE. |
Journal name |
Front Pharmacol
|
Publication year | 2014 |
Sample | Placenta |
Sample name | HTR-8/Svneo |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140214: EV-METRIC:33%
|
|
|
87
|
Experiment ID | 454 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
22669077
|
Organism | Homo sapiens |
Experiment description | The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. |
Authors | Bosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Normal-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
88
|
Experiment ID | 520 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23601281
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of human platelet-derived microparticles. |
Authors | Capriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A. |
Journal name |
Anal Chim Acta
|
Publication year | 2013 |
Sample | Platelets |
Sample name | Platelets purifird from blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
89
|
Experiment ID | 138 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | DU145 - Rep 2 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
90
|
Experiment ID | 277 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Q-TOF]
|
PubMed ID |
22030351
|
Organism | Homo sapiens |
Experiment description | Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways |
Authors | Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM |
Journal name |
MCP
|
Publication year | 2011 |
Sample | Prostate cancer cells |
Sample name | PC-3 |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
91
|
Experiment ID | 633 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DU145 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
92
|
Experiment ID | 634 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | PC-3 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
93
|
Experiment ID | 851 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
94
|
Experiment ID | 853 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS - Rep 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
95
|
Experiment ID | 855 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS with DHT treatment - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
96
|
Experiment ID | 857 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28881726
|
Organism | Homo sapiens |
Experiment description | Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer |
Authors | Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Prostate cancer cells |
Sample name | DUCaP - in CSS with DHT treatment - Rep 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
|
|
|
97
|
Experiment ID | 963 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25844599
|
Organism | Homo sapiens |
Experiment description | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors | Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | DU145 Tax-Sen |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150027: EV-METRIC:11%, 56%
|
|
|
98
|
Experiment ID | 1256 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24400796
|
Organism | Homo sapiens |
Experiment description | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. |
Authors | Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. |
Journal name |
J Proteome Res.
|
Publication year | 2014 |
Sample | Retinal pigment epithelial cells |
Sample name | ARPE-19 |
Isolation/purification methods | ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140174: EV-METRIC:13%, 13%
|
|
|
99
|
Experiment ID | 66 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
19199708
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR |
Journal name |
JPR
|
Publication year | 2009 |
Sample | Saliva |
Sample name | Saliva |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting Immunoelectron microscopy |
EV-TRACK |
-
|
|
|
100
|
Experiment ID | 1138 |
Identified molecule | protein
|
Extracellular vesicle type | Prostasomes |
Identification method | Mass spectrometry
|
PubMed ID |
23707955
|
Organism | Homo sapiens |
Experiment description | Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). |
Authors | Ronquist KG, Ek B, Morrell J, Stavreus-Evers A, Ströolst B, Humblot P, Ronquist G, Larsson A. |
Journal name |
Biochim Biophys Acta
|
Publication year | 2013 |
Sample | Seminal plasma |
Sample name | normal male |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1-1.5 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130152: EV-METRIC:14%, 14%
|
|
|
101
|
Experiment ID | 306 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | T cells |
Sample name | CEM T cell - PHA activation |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
102
|
Experiment ID | 307 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | T cells |
Sample name | CEM T cell - ActD activation |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
103
|
Experiment ID | 708 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Control |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
104
|
Experiment ID | 680 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
105
|
Experiment ID | 681 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
106
|
Experiment ID | 682 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
107
|
Experiment ID | 683 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
108
|
Experiment ID | 684 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
109
|
Experiment ID | 685 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
110
|
Experiment ID | 444 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22418980
|
Organism | Homo sapiens |
Experiment description | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors | Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal_high density-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120083: EV-METRIC:22%
|
|
|
111
|
Experiment ID | 445 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22418980
|
Organism | Homo sapiens |
Experiment description | A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors | Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal_low density-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120083: EV-METRIC:22%
|
|
|
112
|
Experiment ID | 478 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
113
|
Experiment ID | 479 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of hernia-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
114
|
Experiment ID | 512 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Low-grade prostate cancer patient-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|
115
|
Experiment ID | 513 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|