Gene description for PCNA
Gene name	proliferating cell nuclear antigen
Gene symbol	PCNA
Other names/aliases	-
Species	Homo sapiens
Database cross references - PCNA
Vesiclepedia	VP_5111
ExoCarta	ExoCarta_5111
Entrez Gene	5111
HGNC	8729
MIM	176740
PCNA identified in extracellular vesicles derived from the following tissue/cell type
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
Astrocytoma cells [Extracellular vesicles]      More >>>	30006486
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes]      More >>>	20458337
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
B cells [Exosomes/Microvesicles/Oncosomes/Microparticles]      More >>>	23818640
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Bladder cancer cells [Extracellular vesicles]      More >>>	29207636
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Breast cancer cells [Extracellular vesicles]      More >>>	27894104
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Bronchial epithelial cells [Extracellular vesicles]      More >>>	29127410
Chronic lymphocytic leukemia cells [Exosomes]      More >>>	26100252
Chronic lymphocytic leukemia cells [Exosomes]      More >>>	26100252
Colorectal cancer cells [Exosomes]      More >>>	19837982
Colorectal cancer cells [Microvesicles]      More >>>	19930720
Colorectal cancer cells [Exosomes]      More >>>	22285593
Colorectal cancer cells [Exosomes]      More >>>	22285593
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles]      More >>>	23230278
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Membrane vesicles]      More >>>	23585443
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes]      More >>>	24009881
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Extracellular vesicles]      More >>>	27894104
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Microvesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Colorectal cancer cells [Extracellular vesicles]      More >>>	28842968
Endothelial cells [Membrane vesicles/Extracellular vesicles]      More >>>	23436686
Endothelial cells [Exosomes/Extracellular vesicles]      More >>>	24009886
Epithelial cells [Exosomes]      More >>>	25776846
Glioblastoma cells [Microvesicles]      More >>>	19011622
Leukemia cells [Extracellular vesicles]      More >>>	27894104
Lung cancer cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Melanoma cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Exosomes]      More >>>	23333927
Ovarian cancer cells [Extracellular vesicles]      More >>>	27894104
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Ovarian cancer cells [Exosomes]      More >>>	24434149
Prostate cancer cells [Exosomes]      More >>>	22030351
Prostate cancer cells [Extracellular vesicles]      More >>>	27894104
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
Prostate cancer cells [Extracellular vesicles]      More >>>	28881726
T cells [Microparticles]      More >>>	16342139
T cells [Microparticles]      More >>>	16342139
T cells [Apoptotic bodies]      More >>>	28811610
T cells [Microvesicles]      More >>>	28811610
T cells [Apoptotic bodies]      More >>>	28811610
T cells [Microvesicles]      More >>>	28811610
T cells [Apoptotic bodies]      More >>>	28811610
Thymus [Exosomes]      More >>>	23844026
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Umblical cord mesenchymal stem cells [Microvesicles]      More >>>	29148239
Urothelial cells [Extracellular vesicles]      More >>>	29207636
Urothelial cells [Extracellular vesicles]      More >>>	29207636
Experiment description of studies that identified PCNA in extracellular vesicles
1 Experiment ID 1059 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 1 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1060 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 2 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 1061 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373 - EVs 3 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 1063 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30006486    Organism Homo sapiens Experiment description The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Authors Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. Journal name Mol Cell Proteomics. Publication year 2018 Sample Astrocytoma cells Sample name U373vIII - EVs 2 Isolation/purification methods Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.09-1.13 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
5 Experiment ID 79 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
6 Experiment ID 80 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
7 Experiment ID 81 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 20458337    Organism Homo sapiens Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. Journal name ICB Publication year 2010 Sample B cells Sample name RN (HLA-DR15) Isolation/purification methods Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [FT-ICR] Western blotting EV-TRACK EV100035: EV-METRIC:44%
8 Experiment ID 534 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name EBV- and KSHV-infected B cells (JSC-1, BC1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
9 Experiment ID 535 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name EBV-infected B cells (#1, HLJ, IM9, CP) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
10 Experiment ID 536 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name KSHV-infected B cell (JC, BC3, BCP1, BCBL1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
11 Experiment ID 537 Identified molecule protein Extracellular vesicle type Exosomes/Microvesicles/Oncosomes/Microparticles Identification method Mass spectrometry PubMed ID 23818640    Organism Homo sapiens Experiment description Modulation of B-cell exosome proteins by gamma herpesvirus infection. Authors Meckes DG Jr, Gunawardena HP, Dekroon RM, Heaton PR, Edwards RH, Ozgur S, Griffith JD, Damania B, Raab-Traub N. Journal name Proc Natl Acad Sci U S A Publication year 2013 Sample B cells Sample name Normal B cells (BJAB) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130064: EV-METRIC:25%
12 Experiment ID 905 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
13 Experiment ID 930 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Bladder cancer cells Sample name TCCSUP Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
14 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
15 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
16 Experiment ID 1207 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 1 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
17 Experiment ID 1208 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 2 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
18 Experiment ID 1209 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 3 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
19 Experiment ID 1210 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 4 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
20 Experiment ID 1211 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultrafiltration and size exclusion chromatography sample 5 Isolation/purification methods Ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
21 Experiment ID 1213 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultracentrifugation, sample 2 Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
22 Experiment ID 1214 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29127410    Organism Homo sapiens Experiment description Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Authors Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Journal name Sci Rep. Publication year 2017 Sample Bronchial epithelial cells Sample name Ultracentrifugation, sample 3 Isolation/purification methods Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170061: EV-METRIC:62%, 50%, 50%
23 Experiment ID 901 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name JVM-3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150015: EV-METRIC:22%, 44%
24 Experiment ID 902 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 26100252    Organism Homo sapiens Experiment description Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Authors Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. Journal name Blood Publication year 2015 Sample Chronic lymphocytic leukemia cells Sample name MEC-1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.17 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS Western blotting EV-TRACK EV150015: EV-METRIC:22%, 44%
25 Experiment ID 21 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry    Supporting data    MS     PubMed ID 19837982    Organism Homo sapiens Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Authors Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson Journal name MCP Publication year 2009 Sample Colorectal cancer cells Sample name LIM1215 Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.10-1.12 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting EV-TRACK EV100013: EV-METRIC:25%, 56%
26 Experiment ID 303 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray [Illumina] PubMed ID 19930720    Organism Homo sapiens Experiment description Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Authors Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS Journal name BMC Genomics Publication year 2009 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods Differential centrifugation Ultrafiltration OptiPrep density gradient Flotation density 1.09 g/mL Molecules identified in the study Protein mRNA Methods used in the study Western blotting RT-PCR Microarray [Illumina] EV-TRACK -
27 Experiment ID 347 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Orbitrap] PubMed ID 22285593    Organism Homo sapiens Experiment description Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Authors Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ Journal name Methods Publication year 2012 Sample Colorectal cancer cells Sample name LIM1863 - Ultracentrifugation Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting EV-TRACK EV120024: EV-METRIC:25%, 33%, 50%
28 Experiment ID 348 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Orbitrap] PubMed ID 22285593    Organism Homo sapiens Experiment description Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Authors Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ Journal name Methods Publication year 2012 Sample Colorectal cancer cells Sample name LIM1863 - EpCAM immunoaffinity Isolation/purification methods Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [Orbitrap] Western blotting EV-TRACK EV120024: EV-METRIC:25%, 33%, 50%
29 Experiment ID 486 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130020: EV-METRIC:38%
30 Experiment ID 487 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130020: EV-METRIC:38%
31 Experiment ID 488 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles Identification method Mass spectrometry PubMed ID 23230278    Organism Homo sapiens Experiment description Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Authors Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Shed vesicles-Colorectal cancer cells (LIM1863) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130020: EV-METRIC:38%
32 Experiment ID 517 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
33 Experiment ID 518 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles Identification method Mass spectrometry PubMed ID 23585443    Organism Homo sapiens Experiment description Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Authors Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. Journal name Proteomics Publication year 2013 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130010: EV-METRIC:44%
34 Experiment ID 549 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW480 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
35 Experiment ID 550 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles/Microvesicles/Ectosomes Identification method Mass spectrometry PubMed ID 24009881    Organism Homo sapiens Experiment description Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Authors Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. Journal name J Extracell Vesicles Publication year 2012 Sample Colorectal cancer cells Sample name SW620 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120013: EV-METRIC:50%
36 Experiment ID 587 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name Colo205 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
37 Experiment ID 591 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name HT29 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
38 Experiment ID 592 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Colorectal cancer cells Sample name KM12 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
39 Experiment ID 696 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- insulin induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
40 Experiment ID 697 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215- non-induced Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170021: EV-METRIC:44%, 44%
41 Experiment ID 1049 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name LIM1215 - NI Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
42 Experiment ID 1050 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28842968    Organism Homo sapiens Experiment description Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Authors Liem M, Ang CS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Colorectal cancer cells Sample name lim1215 - II Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170021: EV-METRIC:44%, 44%
43 Experiment ID 502 Identified molecule protein Extracellular vesicle type Membrane vesicles/Extracellular vesicles Identification method Mass spectrometry PubMed ID 23436686    Organism Homo sapiens Experiment description A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Authors Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. Journal name Proteomics Publication year 2013 Sample Endothelial cells Sample name Serum-starved-Human umbilical vascular endothelial cells Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130048: EV-METRIC:44%
44 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%
45 Experiment ID 861 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 25776846    Organism Homo sapiens Experiment description Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Authors Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. Journal name Immunol Cell Biol Publication year 2015 Sample Epithelial cells Sample name Thymic tissue - culture 1 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV150045: EV-METRIC:25%
46 Experiment ID 203 Identified molecule mrna Extracellular vesicle type Microvesicles Identification method Microarray PubMed ID 19011622    Organism Homo sapiens Experiment description Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Authors Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO Journal name Nat Cell Biol Publication year 2008 Sample Glioblastoma cells Sample name Glioblastoma cells Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein miRNA mRNA Methods used in the study RT-PCR Antibody array Microarray EV-TRACK -
47 Experiment ID 602 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Leukemia cells Sample name CCRF-CEM Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
48 Experiment ID 610 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Lung cancer cells Sample name HOP-62 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
49 Experiment ID 618 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name M14 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
50 Experiment ID 619 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MALME-3M Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
51 Experiment ID 620 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name MDA-MB-435 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
52 Experiment ID 623 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-5 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
53 Experiment ID 492 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name IGROV1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
54 Experiment ID 493 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23333927    Organism Homo sapiens Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes. Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. Journal name J Proteomics Publication year 2013 Sample Ovarian cancer cells Sample name OVCAR-3 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130002: EV-METRIC:67%, 56%
55 Experiment ID 628 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Ovarian cancer cells Sample name OVCAR-4 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
56 Experiment ID 992 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
57 Experiment ID 993 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR433 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
58 Experiment ID 994 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name OVCAR5 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
59 Experiment ID 995 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 24434149    Organism Homo sapiens Experiment description In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Authors Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. Journal name Biochem Biophys Res Commun. Publication year 2014 Sample Ovarian cancer cells Sample name SKOV3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140099: EV-METRIC:44%
60 Experiment ID 277 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry [Q-TOF] PubMed ID 22030351    Organism Homo sapiens Experiment description Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Authors Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM Journal name MCP Publication year 2011 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK -
61 Experiment ID 633 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DU145 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
62 Experiment ID 851 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
63 Experiment ID 852 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
64 Experiment ID 853 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS - Rep 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
65 Experiment ID 855 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DUCaP - in CSS with DHT treatment - Rep 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
66 Experiment ID 1195 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 28881726    Organism Homo sapiens Experiment description Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Authors Soekmadji C, Riches JD, Russell PJ, Ruelcke JE, McPherson S, Wang C, Hovens CM, Corcoran NM; Australian Prostate Cancer Collaboration BioResource, Hill MM, Nelson CC. Journal name Oncotarget. Publication year 2016 Sample Prostate cancer cells Sample name DUCaP, EtOH Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV170047: EV-METRIC:44%, 0%, 44%, 44%, 44%, 33%, 33%, 33%
67 Experiment ID 306 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF] PubMed ID 16342139    Organism Homo sapiens Experiment description Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization Authors Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L Journal name Proteomics Publication year 2006 Sample T cells Sample name CEM T cell - PHA activation Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] EV-TRACK -
68 Experiment ID 307 Identified molecule protein Extracellular vesicle type Microparticles Identification method Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF] PubMed ID 16342139    Organism Homo sapiens Experiment description Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization Authors Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L Journal name Proteomics Publication year 2006 Sample T cells Sample name CEM T cell - ActD activation Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] EV-TRACK -
69 Experiment ID 709 Identified molecule protein Extracellular vesicle type Apoptotic bodies Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Control Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
70 Experiment ID 711 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Activated Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
71 Experiment ID 712 Identified molecule protein Extracellular vesicle type Apoptotic bodies Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Activated Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
72 Experiment ID 714 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Apoptotic Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
73 Experiment ID 715 Identified molecule protein Extracellular vesicle type Apoptotic bodies Identification method Mass spectrometry PubMed ID 28811610    Organism Homo sapiens Experiment description Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. Authors Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. Journal name Sci Rep Publication year 2017 Sample T cells Sample name Jurkat cells - Apoptotic Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170063: EV-METRIC:75%, 75%
74 Experiment ID 538 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23844026    Organism Homo sapiens Experiment description Characterization of human thymic exosomes. Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. Journal name PLoS One Publication year 2013 Sample Thymus Sample name Normal-Thymus Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130018: EV-METRIC:63%
75 Experiment ID 680 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
76 Experiment ID 681 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
77 Experiment ID 682 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Preterm newborns- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
78 Experiment ID 683 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
79 Experiment ID 684 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
80 Experiment ID 685 Identified molecule protein Extracellular vesicle type Microvesicles Identification method Mass spectrometry PubMed ID 29148239    Organism Homo sapiens Experiment description Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Authors Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. Journal name Proteomics Clin Appl Publication year 2018 Sample Umblical cord mesenchymal stem cells Sample name Term infants- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Sonication Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
81 Experiment ID 906 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Urothelial cells Sample name SVHUC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%
82 Experiment ID 931 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29207636    Organism Homo sapiens Experiment description Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Authors Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF. Journal name Oncotarget Publication year 2017 Sample Urothelial cells Sample name SVHUC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV170042: EV-METRIC:22%, 22%, 22%, 14%