Gene description for Rala
Gene name	v-ral simian leukemia viral oncogene homolog A (ras related)
Gene symbol	Rala
Other names/aliases	3010001O15Rik AW322615 Ral Rasl1
Species	Mus musculus
Database cross references - Rala
Vesiclepedia	VP_56044
ExoCarta	ExoCarta_56044
Entrez Gene	56044
Rala identified in extracellular vesicles derived from the following tissue/cell type
Breast cancer cells [Exosomes]      More >>>	29115712
Breast cancer cells [Exosomes]      More >>>	29115712
Breast cancer cells [Exosomes]      More >>>	29115712
Breast cancer cells [Exosomes]      More >>>	29115712
Melanoma cells [Extracellular vesicles]      More >>>	29907695
Melanoma cells [Extracellular vesicles]      More >>>	29907695
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>>	30035390
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>>	30035390
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>>	30035390
Mouse embryonic fibroblasts [Extracellular vesicles]      More >>>	30035390
Mov neuroglial cell [Exosomes]      More >>>	15210972
Osteoblasts [Matrix vesicles]      More >>>	17096383
T cells [Exosomes]      More >>>	23463506
Experiment description of studies that identified Rala in extracellular vesicles
1 Experiment ID 1051 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 67NR Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
2 Experiment ID 1052 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 66cl4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1053 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1054 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 4T1.2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
5 Experiment ID 1168 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29907695    Organism Mus musculus Experiment description Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Authors Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. Journal name EMBO J. Publication year 2018 Sample Melanoma cells Sample name B16F10 (16.5 K) Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry RNA sequencing EV-TRACK -
6 Experiment ID 1169 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 29907695    Organism Mus musculus Experiment description Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Authors Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. Journal name EMBO J. Publication year 2018 Sample Melanoma cells Sample name B16F1 (100 K) Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry RNA sequencing EV-TRACK -
7 Experiment ID 1055 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30035390    Organism Mus musculus Experiment description Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Authors Anand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S. Journal name Proteomics. Publication year 2018 Sample Mouse embryonic fibroblasts Sample name MEFs - WT 10K Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
8 Experiment ID 1056 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30035390    Organism Mus musculus Experiment description Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Authors Anand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S. Journal name Proteomics. Publication year 2018 Sample Mouse embryonic fibroblasts Sample name MEFs - WT exosomes Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
9 Experiment ID 1057 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30035390    Organism Mus musculus Experiment description Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Authors Anand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S. Journal name Proteomics. Publication year 2018 Sample Mouse embryonic fibroblasts Sample name MEFs - Arrdc1 KO 10K Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
10 Experiment ID 1058 Identified molecule protein Extracellular vesicle type Extracellular vesicles Identification method Mass spectrometry PubMed ID 30035390    Organism Mus musculus Experiment description Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Authors Anand S, Foot N, Ang CS, Gembus KM, Keerthikumar S, Adda CG, Mathivanan S, Kumar S. Journal name Proteomics. Publication year 2018 Sample Mouse embryonic fibroblasts Sample name MEFs - Arrdc1 KO exosomes Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
11 Experiment ID 39 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 15210972    Organism Mus musculus Experiment description Cells release prions in association with exosomes. Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G Journal name PNAS Publication year 2004 Sample Mov neuroglial cell Sample name Mov neuroglial cell Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.14 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [QSTAR] Western blotting Immunoelectron microscopy EV-TRACK -
12 Experiment ID 372 Identified molecule protein Extracellular vesicle type Matrix vesicles Identification method Mass spectrometry PubMed ID 17096383    Organism Mus musculus Experiment description Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. Authors Xiao Z, Camalier CE, Nagashima K, Chan KC, Lucas DA, de la Cruz MJ, Gignac M, Lockett S, Issaq HJ, Veenstra TD, Conrads TP, Beck GR Jr. Journal name J Cell Physiol Publication year 2007 Sample Osteoblasts Sample name MC3T3-E1 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
13 Experiment ID 1007 Identified molecule protein Extracellular vesicle type Exosomes Identification method Mass spectrometry PubMed ID 23463506    Organism Mus musculus Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts - CD81 KO mice Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130110: EV-METRIC:22%