Gene description for PSMB4 |
Gene name |
proteasome (prosome, macropain) subunit, beta type, 4 |
Gene symbol |
PSMB4 |
Other names/aliases |
HN3 HsN3 PROS-26 PROS26 |
Species |
Homo sapiens |
Database cross references - PSMB4 |
Vesiclepedia |
VP_5692 |
ExoCarta |
ExoCarta_5692 |
Entrez Gene |
5692 |
HGNC |
9541 |
MIM |
602177 |
PSMB4 identified in extracellular vesicles derived from the following tissue/cell type |
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Microparticles] More >>>
|
16342139
|
Bladder cancer cells [Exosomes] More >>>
|
20224111
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Colorectal cancer cells [Microvesicles] More >>>
|
19930720
|
Colorectal cancer cells [Exosomes] More >>>
|
22285593
|
Colorectal cancer cells [Exosomes] More >>>
|
22285593
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Endothelial cells [Exosomes/Extracellular vesicles] More >>>
|
24009886
|
Epithelial cells [Membrane blebs] More >>>
|
19567368
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Glioblastoma cells [Microvesicles] More >>>
|
19011622
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Extracellular vesicles] More >>>
|
27770278
|
Glioblastoma cells [Exosomes] More >>>
|
29937354
|
Glioblastoma cells [Exosomes] More >>>
|
25261722
|
Keratinocytes [Exosomes] More >>>
|
19530224
|
Keratinocytes [Exosomes] More >>>
|
19530224
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Malignant pleural effusions [Exosomes/Microvesicles/Ectosomes/Microparticles] More >>>
|
23585444
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Mesenchymal stem cells [Exosomes] More >>>
|
Unpublished / Not applicable
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
19389847
|
Neuroblastoma cells [Exosomes] More >>>
|
25053844
|
Osteosarcoma cells [Matrix vesicles] More >>>
|
21515422
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Plasma [Microparticles] More >>>
|
23056467
|
Plasma [Exosomes] More >>>
|
22046311
|
Plasma [Extracellular vesicles] More >>>
|
26154623
|
Platelets [Microparticles] More >>>
|
16212402
|
Platelets [Microparticles] More >>>
|
23601281
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22030351
|
Prostate cancer cells [Exosomes] More >>>
|
24347249
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Red blood cells [Microvesicles/Nanovesicles] More >>>
|
18346024
|
Seminal fluid [Exosomes/Prostasomes] More >>>
|
18819103
|
Serum [Exosomes] More >>>
|
22808001
|
T cells [Exosomes] More >>>
|
28811610
|
T cells [Exosomes] More >>>
|
28811610
|
T cells [Microvesicles] More >>>
|
28811610
|
T cells [Microvesicles] More >>>
|
28811610
|
T cells [Apoptotic bodies] More >>>
|
28811610
|
Thymus [Exosomes] More >>>
|
23844026
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Umblical cord mesenchymal stem cells [Microvesicles] More >>>
|
29148239
|
Urine [Exosomes/Membrane vesicles] More >>>
|
22106071
|
Experiment description of studies that identified PSMB4 in extracellular vesicles |
1
|
Experiment ID | 79 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
2
|
Experiment ID | 80 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
3
|
Experiment ID | 81 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
4
|
Experiment ID | 308 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | B cells |
Sample name | B cells - Chronic B cell lymphoid patient |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 76 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20224111
|
Organism | Homo sapiens |
Experiment description | Proteomics analysis of bladder cancer exosomes. |
Authors | Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. |
Journal name |
MCP
|
Publication year | 2010 |
Sample | Bladder cancer cells |
Sample name | HT1376 |
Isolation/purification methods | Differential centrifugation Sucrose density gradient |
Flotation density | 1.10-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Western blotting FACS |
EV-TRACK |
EV100014: EV-METRIC:38%, 14%, 44%
|
|
|
6
|
Experiment ID | 582 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | SF295 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 584 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | SNB-19 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
10
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
11
|
Experiment ID | 952 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
12
|
Experiment ID | 954 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
13
|
Experiment ID | 956 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
14
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
15
|
Experiment ID | 1207 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 1 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
16
|
Experiment ID | 1208 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 2 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
17
|
Experiment ID | 1209 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 3 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
18
|
Experiment ID | 1210 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 4 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
19
|
Experiment ID | 1211 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 5 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
20
|
Experiment ID | 1212 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 1 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
21
|
Experiment ID | 1214 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 3 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
22
|
Experiment ID | 303 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray [Illumina]
|
PubMed ID |
19930720
|
Organism | Homo sapiens |
Experiment description | Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells |
Authors | Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS |
Journal name |
BMC Genomics
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | Differential centrifugation Ultrafiltration OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein mRNA |
Methods used in the study | Western blotting RT-PCR Microarray [Illumina] |
EV-TRACK |
-
|
|
|
23
|
Experiment ID | 347 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Orbitrap]
|
PubMed ID |
22285593
|
Organism | Homo sapiens |
Experiment description | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. |
Authors | Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ |
Journal name |
Methods
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | LIM1863 - Ultracentrifugation |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV120024: EV-METRIC:25%, 33%, 50%
|
|
|
24
|
Experiment ID | 349 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Orbitrap]
|
PubMed ID |
22285593
|
Organism | Homo sapiens |
Experiment description | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. |
Authors | Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ |
Journal name |
Methods
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | LIM1863 - OptiPrep density gradient |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV120024: EV-METRIC:25%, 33%, 50%
|
|
|
25
|
Experiment ID | 486 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
26
|
Experiment ID | 487 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
27
|
Experiment ID | 488 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Shed vesicles-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
28
|
Experiment ID | 517 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
29
|
Experiment ID | 518 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
30
|
Experiment ID | 696 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- insulin induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
31
|
Experiment ID | 697 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- non-induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
32
|
Experiment ID | 1049 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215 - NI |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
33
|
Experiment ID | 1050 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | lim1215 - II |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
34
|
Experiment ID | 562 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
35
|
Experiment ID | 563 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
36
|
Experiment ID | 564 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
37
|
Experiment ID | 565 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ ORBITRAP]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ ORBITRAP] |
EV-TRACK |
-
|
|
|
38
|
Experiment ID | 925 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P150 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
39
|
Experiment ID | 927 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P450 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
40
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|
41
|
Experiment ID | 177 |
Identified molecule | protein
|
Extracellular vesicle type | Membrane blebs |
Identification method | Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
19567368
|
Organism | Homo sapiens |
Experiment description | Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells |
Authors | Alcazar O, Hawkridge AM, Collier TS, Cousins SW, Bhattacharya SK, Muddiman DC, Marin-Castano ME |
Journal name |
Mol Cell Proteomics
|
Publication year | 2009 |
Sample | Epithelial cells |
Sample name | ARPE-19 (Retinal epithelial cells) |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry [LTQ-FT Ultra] |
EV-TRACK |
-
|
|
|
42
|
Experiment ID | 861 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
43
|
Experiment ID | 862 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 2 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
44
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
45
|
Experiment ID | 1039 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | A172 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
46
|
Experiment ID | 1040 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | LN229 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
47
|
Experiment ID | 1041 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U87MG |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
48
|
Experiment ID | 1042 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
49
|
Experiment ID | 1043 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | T98G |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
50
|
Experiment ID | 1044 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | CCF-STTG1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
51
|
Experiment ID | 1072 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Lethally irradiated GBM157 - apoExo - biorep2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
52
|
Experiment ID | 1243 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of TNF-. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|
53
|
Experiment ID | 398 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
19530224
|
Organism | Homo sapiens |
Experiment description | Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. |
Authors | Chavez-Muñoz C, Kilani RT, Ghahary A. |
Journal name |
J Cell Physiol
|
Publication year | 2009 |
Sample | Keratinocytes |
Sample name | Differentiated-Keratinocytes |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
54
|
Experiment ID | 399 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
19530224
|
Organism | Homo sapiens |
Experiment description | Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. |
Authors | Chavez-Muñoz C, Kilani RT, Ghahary A. |
Journal name |
J Cell Physiol
|
Publication year | 2009 |
Sample | Keratinocytes |
Sample name | Undifferentiated-Keratinocytes |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
55
|
Experiment ID | 596 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | ACHN |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
56
|
Experiment ID | 597 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | CAKI |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
57
|
Experiment ID | 598 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Kidney cancer cells |
Sample name | RXF 393 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
58
|
Experiment ID | 521 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Normal-Madin-Darby canine kidney cell (MDCK) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
59
|
Experiment ID | 522 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Ras-transformed MDCK cells (21D1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
60
|
Experiment ID | 602 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | CCRF-CEM |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
61
|
Experiment ID | 603 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | HL-60 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
62
|
Experiment ID | 605 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | MOLT-4 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
63
|
Experiment ID | 607 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | SR |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
64
|
Experiment ID | 608 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | A549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
65
|
Experiment ID | 610 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | HOP-62 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
66
|
Experiment ID | 615 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H460 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
67
|
Experiment ID | 519 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles/Ectosomes/Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23585444
|
Organism | Homo sapiens |
Experiment description | Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. |
Authors | Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Malignant pleural effusions |
Sample name | Non-small cell lung cancer patient-Lung cancer pleural effusion |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130049: EV-METRIC:38%
|
|
|
68
|
Experiment ID | 617 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | LOX IMVI |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
69
|
Experiment ID | 618 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | M14 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
70
|
Experiment ID | 619 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | MALME-3M |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
71
|
Experiment ID | 621 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-2 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
72
|
Experiment ID | 622 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | SK-MEL-28 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
73
|
Experiment ID | 126 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
Unpublished / Not applicable
|
Organism | Homo sapiens |
Experiment description | Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? |
Authors | Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim |
Journal name |
Mesenchymal Stem Cell Therapy
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | huES9.E1 |
Isolation/purification methods | HPLC |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Antibody array Mass spectrometry |
EV-TRACK |
-
|
|
|
74
|
Experiment ID | 244 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
75
|
Experiment ID | 310 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 2 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
76
|
Experiment ID | 394 |
Identified molecule | mRNA
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19389847
|
Organism | Homo sapiens |
Experiment description | Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. |
Authors | Bruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, Tetta C, Camussi G. |
Journal name |
J Am Soc Nephrol
|
Publication year | 2009 |
Sample | Mesenchymal stem cells |
Sample name | Normal-Mesenchymal stem cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | mRNA |
Methods used in the study | Microarray |
EV-TRACK |
-
|
|
|
77
|
Experiment ID | 903 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25053844
|
Organism | Homo sapiens |
Experiment description | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons |
Authors | Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ. |
Journal name |
Nucleic Acids Res
|
Publication year | 2014 |
Sample | Neuroblastoma cells |
Sample name | SH-SY5Y |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140076: EV-METRIC:38%
|
|
|
78
|
Experiment ID | 428 |
Identified molecule | protein
|
Extracellular vesicle type | Matrix vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
21515422
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. |
Authors | Thouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S. |
Journal name |
J Proteomics
|
Publication year | 2011 |
Sample | Osteosarcoma cells |
Sample name | Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
79
|
Experiment ID | 492 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | IGROV1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
80
|
Experiment ID | 493 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-3 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
81
|
Experiment ID | 628 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-4 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
82
|
Experiment ID | 992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
83
|
Experiment ID | 993 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR433 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
84
|
Experiment ID | 994 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
85
|
Experiment ID | 995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | SKOV3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
86
|
Experiment ID | 473 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23056467
|
Organism | Homo sapiens |
Experiment description | Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. |
Authors | Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Patients of external counterpulsation therapy-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
87
|
Experiment ID | 863 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22046311
|
Organism | Mus musculus |
Experiment description | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections |
Authors | Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA. |
Journal name |
PLoS One
|
Publication year | 2011 |
Sample | Plasma |
Sample name | Peripheral blood plasma - P. yoelii 17X infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS Mass spectrometry |
EV-TRACK |
EV110102: EV-METRIC:25%, 25%
|
|
|
88
|
Experiment ID | 1226 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
26154623
|
Organism | Homo sapiens |
Experiment description | Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals |
Authors | de Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2015 |
Sample | Plasma |
Sample name | Donar 1 fr7+8 |
Isolation/purification methods | Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150034: EV-METRIC:17%, 57%
|
|
|
89
|
Experiment ID | 369 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
16212402
|
Organism | Homo sapiens |
Experiment description | The platelet microparticle proteome. |
Authors | Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. |
Journal name |
J Proteome Res
|
Publication year | 2005 |
Sample | Platelets |
Sample name | Normal donors-Platelets |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
90
|
Experiment ID | 520 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
23601281
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of human platelet-derived microparticles. |
Authors | Capriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A. |
Journal name |
Anal Chim Acta
|
Publication year | 2013 |
Sample | Platelets |
Sample name | Platelets purifird from blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
91
|
Experiment ID | 139 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | DU145 - Rep 3 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
92
|
Experiment ID | 141 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | VCaP - Rep 3 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
93
|
Experiment ID | 277 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Q-TOF]
|
PubMed ID |
22030351
|
Organism | Homo sapiens |
Experiment description | Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways |
Authors | Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM |
Journal name |
MCP
|
Publication year | 2011 |
Sample | Prostate cancer cells |
Sample name | PC-3 |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
94
|
Experiment ID | 1121 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24347249
|
Organism | Homo sapiens |
Experiment description | Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. |
Authors | Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. |
Journal name |
Mol Carcinog
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | LNCaP- Hypoxic |
Isolation/purification methods | Differential centrifugation Ultracentrifugation ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140124: EV-METRIC:43%, 25%
|
|
|
95
|
Experiment ID | 376 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Microvesicle, Storage day 21-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
96
|
Experiment ID | 377 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Microvesicle, Storage day 3-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
97
|
Experiment ID | 378 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Microvesicle, Storage day 42-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
98
|
Experiment ID | 379 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Nanovesicle, Storage day 21-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
99
|
Experiment ID | 380 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Nanovesicle, Storage day 3-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
100
|
Experiment ID | 381 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
18346024
|
Organism | Homo sapiens |
Experiment description | The proteome of red cell membranes and vesicles during storage in blood bank conditions. |
Authors | Bosman GJ1, Lasonder E, Luten M, Roerdinkholder-Stoelwinder B, Novotnà VM, Bos H, De Grip WJ. |
Journal name |
Transfusion
|
Publication year | 2008 |
Sample | Red blood cells |
Sample name | Nanovesicle, Storage day 42-Red blood cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
101
|
Experiment ID | 389 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Prostasomes |
Identification method | Mass spectrometry
|
PubMed ID |
18819103
|
Organism | Homo sapiens |
Experiment description | Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. |
Authors | Poliakov A, Spilman M, Dokland T, Amling CL, Mobley JA. |
Journal name |
Prostate
|
Publication year | 2009 |
Sample | Seminal fluid |
Sample name | Normal donors-Seminal fluid |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
102
|
Experiment ID | 971 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
22808001
|
Organism | Homo sapiens |
Experiment description | Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. |
Authors | Musante L, Saraswat M, Duriez E, Byrne B, Ravidà, Domon B, Holthofer H. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Serum |
Sample name | Serum -Tuberculosis patient 1 |
Isolation/purification methods | Filtration ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120006: EV-METRIC:56%
|
|
|
103
|
Experiment ID | 707 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Control |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
104
|
Experiment ID | 710 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Activated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
105
|
Experiment ID | 711 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Activated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
106
|
Experiment ID | 714 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
107
|
Experiment ID | 715 |
Identified molecule | protein
|
Extracellular vesicle type | Apoptotic bodies |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
108
|
Experiment ID | 538 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23844026
|
Organism | Homo sapiens |
Experiment description | Characterization of human thymic exosomes. |
Authors | Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Thymus |
Sample name | Normal-Thymus |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130018: EV-METRIC:63%
|
|
|
109
|
Experiment ID | 680 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
110
|
Experiment ID | 681 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
111
|
Experiment ID | 682 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Preterm newborns- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
112
|
Experiment ID | 683 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
113
|
Experiment ID | 684 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
114
|
Experiment ID | 685 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29148239
|
Organism | Homo sapiens |
Experiment description | Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. |
Authors | Bruschi M, Santucci L, Ravera S, Bartolucci M, Petretto A, Calzia D, Ghiggeri GM, Ramenghi LA, Candiano G, Panfoli I. |
Journal name |
Proteomics Clin Appl
|
Publication year | 2018 |
Sample | Umblical cord mesenchymal stem cells |
Sample name | Term infants- replicate 3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sonication Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
115
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
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