Gene description for RPS5 |
Gene name |
ribosomal protein S5 |
Gene symbol |
RPS5 |
Other names/aliases |
S5 |
Species |
Homo sapiens |
Database cross references - RPS5 |
Vesiclepedia |
VP_6193 |
ExoCarta |
ExoCarta_6193 |
Entrez Gene |
6193 |
HGNC |
10426 |
MIM |
603630 |
RPS5 identified in extracellular vesicles derived from the following tissue/cell type |
Astrocytoma cells [Extracellular vesicles] More >>>
|
30006486
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Exosomes] More >>>
|
20458337
|
B cells [Microparticles] More >>>
|
16342139
|
Brain cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Breast cancer cells [Extracellular vesicles] More >>>
|
26378940
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Breast milk [Extracellular vesicles] More >>>
|
27601599
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Bronchial epithelial cells [Extracellular vesicles] More >>>
|
29127410
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Chronic lymphocytic leukemia cells [Exosomes] More >>>
|
26100252
|
Colorectal cancer cells [Microvesicles] More >>>
|
19930720
|
Colorectal cancer cells [Exosomes] More >>>
|
22285593
|
Colorectal cancer cells [Exosomes] More >>>
|
22285593
|
Colorectal cancer cells [Exosomes] More >>>
|
22285593
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles] More >>>
|
23230278
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Membrane vesicles] More >>>
|
23585443
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Exosomes/Extracellular vesicles/Microvesicles/Ectosomes] More >>>
|
24009881
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Microvesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Colorectal cancer cells [Extracellular vesicles] More >>>
|
28842968
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Microvesicles] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Dendritic cells [Exosomes] More >>>
|
26858453
|
Embryonic kidney cells [Exosomes] More >>>
|
25483805
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
18563738
|
Endothelial cells [Microparticles] More >>>
|
19369228
|
Endothelial cells [Membrane vesicles/Extracellular vesicles] More >>>
|
23436686
|
Endothelial cells [Exosomes/Extracellular vesicles] More >>>
|
24009886
|
Epithelial cells [Exosomes] More >>>
|
25776846
|
Glioblastoma cells [Microvesicles] More >>>
|
19011622
|
Glioblastoma cells [Exosomes] More >>>
|
25261722
|
Glioblastoma cells [Exosomes] More >>>
|
25261722
|
Hepatocytes [Microvesicles] More >>>
|
19650833
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Kidney cells [Exosomes/Extracellular vesicles] More >>>
|
23645497
|
Leukemia cells [Extracellular vesicles] More >>>
|
27894104
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Leukemia cells [Exosomes] More >>>
|
24939845
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Lung cancer cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Melanoma cells [Extracellular vesicles] More >>>
|
27894104
|
Mesenchymal stem cells [Exosomes] More >>>
|
Unpublished / Not applicable
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Mesenchymal stem cells [Microvesicles] More >>>
|
22148876
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neonatal myoblast cells [Microvesicles/Nanovesicles] More >>>
|
23000592
|
Neuroblastoma cells [Exosomes/Membrane vesicles] More >>>
|
24069378
|
Neuroblastoma cells [Exosomes] More >>>
|
25053844
|
Osteosarcoma cells [Matrix vesicles] More >>>
|
21515422
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Exosomes] More >>>
|
23333927
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Ovarian cancer cells [Exosomes] More >>>
|
24434149
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
22723089
|
Prostate cancer cells [Exosomes] More >>>
|
25844599
|
Prostate cancer cells [Exosomes] More >>>
|
25844599
|
Retinal pigment epithelial cells [Exosomes] More >>>
|
24400796
|
T cells [Microparticles] More >>>
|
16342139
|
T cells [Microparticles] More >>>
|
16342139
|
T cells [Exosomes] More >>>
|
28811610
|
T cells [Exosomes] More >>>
|
28811610
|
T cells [Exosomes] More >>>
|
28811610
|
T cells [Apoptotic bodies] More >>>
|
28811610
|
T cells [Exosomes] More >>>
|
23463506
|
Thymus [Exosomes] More >>>
|
23844026
|
Urine [Exosomes/Membrane vesicles] More >>>
|
22106071
|
Experiment description of studies that identified RPS5 in extracellular vesicles |
1
|
Experiment ID | 1064 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
30006486
|
Organism | Homo sapiens |
Experiment description | The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. |
Authors | Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J. |
Journal name |
Mol Cell Proteomics.
|
Publication year | 2018 |
Sample | Astrocytoma cells |
Sample name | U373vIII - EVs 3 |
Isolation/purification methods | Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.13 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 79 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
3
|
Experiment ID | 80 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
4
|
Experiment ID | 81 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
20458337
|
Organism | Homo sapiens |
Experiment description | MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 |
Authors | Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. |
Journal name |
ICB
|
Publication year | 2010 |
Sample | B cells |
Sample name | RN (HLA-DR15) |
Isolation/purification methods | Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II) |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [FT-ICR] Western blotting |
EV-TRACK |
EV100035: EV-METRIC:44%
|
|
|
5
|
Experiment ID | 308 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | B cells |
Sample name | B cells - Chronic B cell lymphoid patient |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 586 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Brain cancer cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 577 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 578 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1028 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
26378940
|
Organism | Homo sapiens |
Experiment description | Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. |
Authors | Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. |
Journal name |
Anal Chem.
|
Publication year | 2015 |
Sample | Breast cancer cells |
Sample name | SKBR3B - 10 K pellet |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150004: EV-METRIC:67%, 38%
|
|
|
11
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
12
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
13
|
Experiment ID | 955 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D6 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
14
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
15
|
Experiment ID | 1207 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 1 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
16
|
Experiment ID | 1208 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 2 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
17
|
Experiment ID | 1209 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 3 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
18
|
Experiment ID | 1210 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 4 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
19
|
Experiment ID | 1211 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultrafiltration and size exclusion chromatography sample 5 |
Isolation/purification methods | Ultrafiltration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
20
|
Experiment ID | 1212 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 1 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
21
|
Experiment ID | 1213 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 2 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
22
|
Experiment ID | 1214 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
29127410
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. |
Authors | Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. |
Journal name |
Sci Rep.
|
Publication year | 2017 |
Sample | Bronchial epithelial cells |
Sample name | Ultracentrifugation, sample 3 |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170061: EV-METRIC:62%, 50%, 50%
|
|
|
23
|
Experiment ID | 899 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | CLL cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
24
|
Experiment ID | 901 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | JVM-3 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
25
|
Experiment ID | 902 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
26100252
|
Organism | Homo sapiens |
Experiment description | Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts |
Authors | Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E. |
Journal name |
Blood
|
Publication year | 2015 |
Sample | Chronic lymphocytic leukemia cells |
Sample name | MEC-1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.15-1.17 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry FACS Western blotting |
EV-TRACK |
EV150015: EV-METRIC:22%, 44%
|
|
|
26
|
Experiment ID | 303 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray [Illumina]
|
PubMed ID |
19930720
|
Organism | Homo sapiens |
Experiment description | Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells |
Authors | Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS |
Journal name |
BMC Genomics
|
Publication year | 2009 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | Differential centrifugation Ultrafiltration OptiPrep density gradient |
Flotation density | 1.09 g/mL |
Molecules identified in the study | Protein mRNA |
Methods used in the study | Western blotting RT-PCR Microarray [Illumina] |
EV-TRACK |
-
|
|
|
27
|
Experiment ID | 347 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Orbitrap]
|
PubMed ID |
22285593
|
Organism | Homo sapiens |
Experiment description | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. |
Authors | Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ |
Journal name |
Methods
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | LIM1863 - Ultracentrifugation |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV120024: EV-METRIC:25%, 33%, 50%
|
|
|
28
|
Experiment ID | 349 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Orbitrap]
|
PubMed ID |
22285593
|
Organism | Homo sapiens |
Experiment description | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. |
Authors | Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ |
Journal name |
Methods
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | LIM1863 - OptiPrep density gradient |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV120024: EV-METRIC:25%, 33%, 50%
|
|
|
29
|
Experiment ID | 348 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [Orbitrap]
|
PubMed ID |
22285593
|
Organism | Homo sapiens |
Experiment description | Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. |
Authors | Tauro BJ, Greening DW, Mathias RA, Ji H, Mathivanan S, Scott AM, Simpson RJ |
Journal name |
Methods
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | LIM1863 - EpCAM immunoaffinity |
Isolation/purification methods | Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap] Western blotting |
EV-TRACK |
EV120024: EV-METRIC:25%, 33%, 50%
|
|
|
30
|
Experiment ID | 486 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
31
|
Experiment ID | 487 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
32
|
Experiment ID | 488 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23230278
|
Organism | Homo sapiens |
Experiment description | Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. |
Authors | Tauro BJ, Greening DW, Mathias RA, Mathivanan S, Ji H, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | Shed vesicles-Colorectal cancer cells (LIM1863) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130020: EV-METRIC:38%
|
|
|
33
|
Experiment ID | 517 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
34
|
Experiment ID | 518 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23585443
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. |
Authors | Ji H, Greening DW, Barnes TW, Lim JW, Tauro BJ, Rai A, Xu R, Adda C, Mathivanan S, Zhao W, Xue Y, Xu T, Zhu HJ, Simpson RJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130010: EV-METRIC:44%
|
|
|
35
|
Experiment ID | 549 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW480 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
36
|
Experiment ID | 550 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles/Microvesicles/Ectosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24009881
|
Organism | Homo sapiens |
Experiment description | Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. |
Authors | Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP, Gho YS. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Colorectal cancer cells |
Sample name | SW620 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120013: EV-METRIC:50%
|
|
|
37
|
Experiment ID | 592 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Colorectal cancer cells |
Sample name | KM12 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
38
|
Experiment ID | 696 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- insulin induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
39
|
Experiment ID | 697 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215- non-induced |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
40
|
Experiment ID | 1049 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | LIM1215 - NI |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
41
|
Experiment ID | 1050 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
28842968
|
Organism | Homo sapiens |
Experiment description | Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. |
Authors | Liem M, Ang CS, Mathivanan S. |
Journal name |
Proteomics.
|
Publication year | 2017 |
Sample | Colorectal cancer cells |
Sample name | lim1215 - II |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV170021: EV-METRIC:44%, 44%
|
|
|
42
|
Experiment ID | 562 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
43
|
Experiment ID | 563 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 10K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
44
|
Experiment ID | 564 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F3 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
45
|
Experiment ID | 565 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ ORBITRAP]
|
PubMed ID |
26858453
|
Organism | Homo sapiens |
Experiment description | Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes |
Authors | Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thé C |
Journal name |
PNAS
|
Publication year | 2016 |
Sample | Dendritic cells |
Sample name | monocyte-derived dendritic cells (F5 100K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density | 1.14 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ ORBITRAP] |
EV-TRACK |
-
|
|
|
46
|
Experiment ID | 925 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25483805
|
Organism | Homo sapiens |
Experiment description | Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties |
Authors | Vyas N, Walvekar A, Tate D, Lakshmanan V, Bansal D, Lo Cicero A, Raposo G, Palakodeti D, Dhawan J. |
Journal name |
Sci Rep
|
Publication year | 2014 |
Sample | Embryonic kidney cells |
Sample name | HEK293T - P150 - Fraction 1.12 g/mL |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.09-1.12 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140018: EV-METRIC:56%, 56%
|
|
|
47
|
Experiment ID | 385 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
48
|
Experiment ID | 386 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by PAI-1-Endothelial cell (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
49
|
Experiment ID | 387 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
18563738
|
Organism | Homo sapiens |
Experiment description | Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. |
Authors | Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. |
Journal name |
Proteomics
|
Publication year | 2008 |
Sample | Endothelial cells |
Sample name | Treated by TNF-alpha-Endothelial cells (HUVEC) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
50
|
Experiment ID | 393 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry
|
PubMed ID |
19369228
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. |
Authors | Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. |
Journal name |
Blood
|
Publication year | 2009 |
Sample | Endothelial cells |
Sample name | Normal-Endothelial progenitor cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
51
|
Experiment ID | 502 |
Identified molecule | protein
|
Extracellular vesicle type | Membrane vesicles/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23436686
|
Organism | Homo sapiens |
Experiment description | A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. |
Authors | Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, Rondeau C, Thibault P, Desjardins M, Hebert MJ. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Endothelial cells |
Sample name | Serum-starved-Human umbilical vascular endothelial cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130048: EV-METRIC:44%
|
|
|
52
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|
53
|
Experiment ID | 862 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25776846
|
Organism | Homo sapiens |
Experiment description | Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens |
Authors | Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, Ekwall O. |
Journal name |
Immunol Cell Biol
|
Publication year | 2015 |
Sample | Epithelial cells |
Sample name | Thymic tissue - culture 2 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150045: EV-METRIC:25%
|
|
|
54
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
55
|
Experiment ID | 1242 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of IL-1. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|
56
|
Experiment ID | 1243 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of TNF-. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|
57
|
Experiment ID | 405 |
Identified molecule | mRNA
|
Extracellular vesicle type | Microvesicles |
Identification method | Microarray
|
PubMed ID |
19650833
|
Organism | Homo sapiens |
Experiment description | Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. |
Authors | Herrera MB, Fonsato V, Gatti S, Deregibus MC, Sordi A, Cantarella D, Calogero R, Bussolati B, Tetta C, Camussi G. |
Journal name |
J Cell Mol Med
|
Publication year | 2010 |
Sample | Hepatocytes |
Sample name | Normal-Hepatocytes |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | mRNA |
Methods used in the study | Microarray |
EV-TRACK |
-
|
|
|
58
|
Experiment ID | 521 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Normal-Madin-Darby canine kidney cell (MDCK) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
59
|
Experiment ID | 522 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23645497
|
Organism | Canis lupus familiaris |
Experiment description | Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. |
Authors | Tauro BJ, Mathias RA, Greening DW, Gopal SK, Ji H, Kapp EA, Coleman BM, Hill AF, Kusebauch U, Hallows JL, Shteynberg D, Moritz RL, Zhu HJ, Simpson RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year | 2013 |
Sample | Kidney cells |
Sample name | Ras-transformed MDCK cells (21D1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130021: EV-METRIC:50%
|
|
|
60
|
Experiment ID | 602 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Leukemia cells |
Sample name | CCRF-CEM |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
61
|
Experiment ID | 1248 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | CEM - uninfected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
62
|
Experiment ID | 1250 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24939845
|
Organism | Homo sapiens |
Experiment description | Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. |
Authors | Jaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F. |
Journal name |
J Biol Chem.
|
Publication year | 2014 |
Sample | Leukemia cells |
Sample name | MT2 - HTLV-1 infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140028: EV-METRIC:33%
|
|
|
63
|
Experiment ID | 612 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H226 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
64
|
Experiment ID | 615 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Lung cancer cells |
Sample name | NCI-H460 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
65
|
Experiment ID | 617 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | LOX IMVI |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
66
|
Experiment ID | 625 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Melanoma cells |
Sample name | UACC-62 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
67
|
Experiment ID | 126 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
Unpublished / Not applicable
|
Organism | Homo sapiens |
Experiment description | Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? |
Authors | Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim |
Journal name |
Mesenchymal Stem Cell Therapy
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | huES9.E1 |
Isolation/purification methods | HPLC |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Antibody array Mass spectrometry |
EV-TRACK |
-
|
|
|
68
|
Experiment ID | 244 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 1 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
69
|
Experiment ID | 310 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 2 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
70
|
Experiment ID | 311 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
Identification method | Mass spectrometry[Q-TOF]
|
PubMed ID |
22148876
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of microvesicles derived from human mesenchymal stem cells |
Authors | Kim HS, Choi DY, Yun SJ, Choi SM, Kang JW, Jung JW, Hwang D, Kim KP, Kim DW |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Mesenchymal stem cells |
Sample name | Mesenchymal stem cells - Rep 3 |
Isolation/purification methods | Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry[QTOF] |
EV-TRACK |
-
|
|
|
71
|
Experiment ID | 467 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_exosome-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
72
|
Experiment ID | 468 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles/Nanovesicles |
Identification method | Mass spectrometry
|
PubMed ID |
23000592
|
Organism | Homo sapiens |
Experiment description | In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. |
Authors | Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lain챕 J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Neonatal myoblast cells |
Sample name | Patient of developmental heart defect_microparticle-Neonatal myoblast cells |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
73
|
Experiment ID | 556 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
24069378
|
Organism | Homo sapiens |
Experiment description | Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. |
Authors | Marimpietri D, Petretto A, Raffaghello L, Pezzolo A, Gagliani C, Tacchetti C, Mauri P, Melioli G, Pistoia V. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Neuroblastoma cells |
Sample name | HTLA-230 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130101: EV-METRIC:38%, 14%
|
|
|
74
|
Experiment ID | 903 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25053844
|
Organism | Homo sapiens |
Experiment description | Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons |
Authors | Goldie BJ, Dun MD, Lin M, Smith ND, Verrills NM, Dayas CV, Cairns MJ. |
Journal name |
Nucleic Acids Res
|
Publication year | 2014 |
Sample | Neuroblastoma cells |
Sample name | SH-SY5Y |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140076: EV-METRIC:38%
|
|
|
75
|
Experiment ID | 428 |
Identified molecule | protein
|
Extracellular vesicle type | Matrix vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
21515422
|
Organism | Homo sapiens |
Experiment description | Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. |
Authors | Thouverey C, Malinowska A, Balcerzak M, Strzelecka-Kiliszek A, Buchet R, Dadlez M, Pikula S. |
Journal name |
J Proteomics
|
Publication year | 2011 |
Sample | Osteosarcoma cells |
Sample name | Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
76
|
Experiment ID | 492 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | IGROV1 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
77
|
Experiment ID | 493 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23333927
|
Organism | Homo sapiens |
Experiment description | Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors | Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Ovarian cancer cells |
Sample name | OVCAR-3 |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130002: EV-METRIC:67%, 56%
|
|
|
78
|
Experiment ID | 992 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
79
|
Experiment ID | 993 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR433 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
80
|
Experiment ID | 994 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | OVCAR5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
81
|
Experiment ID | 995 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24434149
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. |
Authors | Sinha A, Ignatchenko V, Ignatchenko A, Mejia-Guerrero S, Kislinger T. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Ovarian cancer cells |
Sample name | SKOV3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140099: EV-METRIC:44%
|
|
|
82
|
Experiment ID | 139 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | DU145 - Rep 3 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
83
|
Experiment ID | 140 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | VCaP - Rep 2 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
84
|
Experiment ID | 142 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | LNCaP - Rep 2 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
85
|
Experiment ID | 143 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | LNCaP - Rep 3 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
86
|
Experiment ID | 144 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry [QTOF] | |
Supporting data | |
MSS | |
PubMed ID |
22723089
|
Organism | Homo sapiens |
Experiment description | Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. |
Authors | Hosseini-Beheshti E, Guns ES. |
Journal name |
MCP
|
Publication year | 2012 |
Sample | Prostate cancer cells |
Sample name | C4-2 - Rep 2 |
Isolation/purification methods | Sucrose density gradient |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QTOF] |
EV-TRACK |
EV120018: EV-METRIC:38%
|
|
|
87
|
Experiment ID | 963 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25844599
|
Organism | Homo sapiens |
Experiment description | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors | Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | DU145 Tax-Sen |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.19 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150027: EV-METRIC:11%, 56%
|
|
|
88
|
Experiment ID | 964 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
25844599
|
Organism | Homo sapiens |
Experiment description | Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors | Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year | 2015 |
Sample | Prostate cancer cells |
Sample name | DU145 Tax-Res |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.13-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150027: EV-METRIC:11%, 56%
|
|
|
89
|
Experiment ID | 1256 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
24400796
|
Organism | Homo sapiens |
Experiment description | Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. |
Authors | Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. |
Journal name |
J Proteome Res.
|
Publication year | 2014 |
Sample | Retinal pigment epithelial cells |
Sample name | ARPE-19 |
Isolation/purification methods | ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140174: EV-METRIC:13%, 13%
|
|
|
90
|
Experiment ID | 306 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | T cells |
Sample name | CEM T cell - PHA activation |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
91
|
Experiment ID | 307 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
Identification method | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [Q-TOF]
|
PubMed ID |
16342139
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization |
Authors | Miguet L, Pacaud K, Felden C, Hugel B, Martinez MC, Freyssinet JM, Herbrecht R, Potier N, van Dorsselaer A, Mauvieux L |
Journal name |
Proteomics
|
Publication year | 2006 |
Sample | T cells |
Sample name | CEM T cell - ActD activation |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [MALDI TOF/TOF] Mass spectrometry [QTOF] |
EV-TRACK |
-
|
|
|
92
|
Experiment ID | 707 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Control |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
93
|
Experiment ID | 710 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Activated |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
94
|
Experiment ID | 713 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
95
|
Experiment ID | 715 |
Identified molecule | protein
|
Extracellular vesicle type | Apoptotic bodies |
Identification method | Mass spectrometry
|
PubMed ID |
28811610
|
Organism | Homo sapiens |
Experiment description | Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. |
Authors | Néth A, Orgovan N, Só BW, Osteikoetxea X, Páczi K, Szabóylor KÉ Vukman KV, Kittel Á TuriáL, Wiener Z, TóS, Drahos L, Véy K, Horvath R, BuzáEI. |
Journal name |
Sci Rep
|
Publication year | 2017 |
Sample | T cells |
Sample name | Jurkat cells - Apoptotic |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170063: EV-METRIC:75%, 75%
|
|
|
96
|
Experiment ID | 1008 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23463506
|
Organism | Homo sapiens |
Experiment description | The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. |
Authors | Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó |
Journal name |
J Biol Chem.
|
Publication year | 2013 |
Sample | T cells |
Sample name | T lymphoblasts |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130110: EV-METRIC:22%
|
|
|
97
|
Experiment ID | 538 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
Identification method | Mass spectrometry
|
PubMed ID |
23844026
|
Organism | Homo sapiens |
Experiment description | Characterization of human thymic exosomes. |
Authors | Skogberg G, Gudmundsdottir J, van der Post S, Sandström K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year | 2013 |
Sample | Thymus |
Sample name | Normal-Thymus |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130018: EV-METRIC:63%
|
|
|
98
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
|
|