Gene description for TCF7L2
Gene name transcription factor 7-like 2 (T-cell specific, HMG-box)
Gene symbol TCF7L2
Other names/aliases TCF-4
TCF4
Species Homo sapiens
 Database cross references - TCF7L2
Vesiclepedia VP_6934
ExoCarta ExoCarta_6934
Entrez Gene 6934
HGNC 11641
MIM 602228
 TCF7L2 identified in extracellular vesicles derived from the following tissue/cell type
Colorectal cancer cells [Microvesicles]      More >>> 19930720   
Mesenchymal stem cells [Microvesicles]      More >>> 19389847   
 Experiment description of studies that identified TCF7L2 in extracellular vesicles
1
Experiment ID303
Identified moleculemrna
Extracellular vesicle typeMicrovesicles
Identification method Microarray [Illumina]
PubMed ID 19930720   
OrganismHomo sapiens
Experiment descriptionColorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells
AuthorsHong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D, Gho YS
Journal name BMC Genomics
Publication year2009
SampleColorectal cancer cells
Sample nameSW480
Isolation/purification methodsDifferential centrifugation
Ultrafiltration
Optiprep density gradient
Flotation density1.098 g/mL
Molecules identified in the studyProtein
mRNA
Methods used in the studyWestern blotting
RT-PCR
Microarray [Illumina]
2
Experiment ID394
Identified moleculemRNA
Extracellular vesicle typeMicrovesicles
Identification method Microarray
PubMed ID 19389847   
OrganismHomo sapiens
Experiment descriptionMesenchymal stem cell-derived microvesicles protect against acute tubular injury.
AuthorsBruno S, Grange C, Deregibus MC, Calogero RA, Saviozzi S, Collino F, Morando L, Busca A, Falda M, Bussolati B, Tetta C, Camussi G.
Journal name J Am Soc Nephrol
Publication year2009
SampleMesenchymal stem cells
Sample nameNormal-Mesenchymal stem cells
Isolation/purification methods-
Flotation density-
Molecules identified in the studymRNA
Methods used in the studyMicroarray