Description for Phosphatidylcholine (PC) |
| Lipid |
Phosphatidylcholine (PC) |
| Species |
Mus musculus |
Phosphatidylcholine (PC) identified in exosomes derived from the following tissue/cell type |
|
Forebrain neurons [Extracellular vesicles]
|
29348617
|
|
Forebrain neurons [Extracellular vesicles]
|
29348617
|
|
Neuroblastoma cells [Extracellular vesicles]
|
29348617
|
|
Neuroblastoma cells [Extracellular vesicles]
|
29348617
|
|
Neuroblastoma cells [Extracellular vesicles]
|
29348617
|
|
Oligodendrocytes [Exosomes]
|
18309083
|
|
Primary cortical neurons [Extracellular vesicles]
|
29348617
|
|
Primary cortical neurons [Extracellular vesicles]
|
29348617
|
Experiment description of studies that identified Phosphatidylcholine (PC) in exosomes |
| 1
|
| Experiment ID | 1645 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Forebrain neurons |
| Sample name | C57BL/6 Pik3c3flox/flox |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 1646 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Forebrain neurons |
| Sample name | C57BL/6 Pik3c3flox/flox crossed with transgenic C57BL/6 CaMKIIα-Cre |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 1631 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Neuroblastoma cells |
| Sample name | N2a |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 1632 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Neuroblastoma cells |
| Sample name | N2a |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 1637 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Neuroblastoma cells |
| Sample name | N2a |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 130 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry [QTOF]
|
| PubMed ID |
18309083
|
| Organism | Mus musculus |
| Experiment description | Ceramide triggers budding of exosome vesicles into multivesicular endosomes |
| Authors | Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, Schwille P, BrüB, Simons M. |
| Journal name |
SCIENCE
|
| Publication year | 2008 |
| Sample | Oligodendrocytes |
| Sample name | Oli-neu cells |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Western blotting Mass spectrometry[QTOF] |
| EV-TRACK |
-
|
|
|
| 7
|
| Experiment ID | 1629 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Primary cortical neurons |
| Sample name | C57BL/6 |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|
| 8
|
| Experiment ID | 1630 |
| Identified molecule | Lipid
|
| Identification method | LC-MS
|
| PubMed ID |
29348617
|
| Organism | Mus musculus |
| Experiment description | Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures |
| Authors | Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. |
| Journal name |
Nat Commun
|
| Publication year | 2018 |
| Sample | Primary cortical neurons |
| Sample name | C57BL/6 |
| Molecules identified in the study | Protein Lipid |
| Methods used in the study | Western blotting LC-MS |
| EV-TRACK |
-
|
|
|