Description for Phosphatidylserine (PS) |
| Lipid |
Phosphatidylserine (PS) |
| Species |
Homo sapiens |
Phosphatidylserine (PS) identified in exosomes derived from the following tissue/cell type |
|
Ascites [Exosomes]
|
19188015
|
|
Atherosclerotic plaques [Apoptotic bodies]
|
9918520
|
|
Dendritic cells [Exosomes]
|
14965343
|
|
Inflammatory fluid [Microvesicles]
|
7697722
|
|
Macrophage [Microvesicles/Exosomes]
|
22711894
|
|
Macrophage [Exosomes]
|
22711894
|
|
Macrophage [Exosomes]
|
22711894
|
|
Macrophage [Exosomes]
|
22711894
|
|
Melanoma cells [Exosomes]
|
19801663
|
|
Ovarian cancer cells [Exosomes]
|
19188015
|
|
Ovarian cancer cells [Exosomes]
|
19188015
|
|
Plasma [Microparticles]
|
12805058
|
|
Plasma [Microparticles]
|
9396452
|
|
Plasma [Microparticles]
|
9396452
|
|
Plasma [Microparticles]
|
12805058
|
|
Plasma [Microparticles]
|
12196479
|
|
Plasma [Microparticles]
|
12196479
|
|
Plasma [Microparticles]
|
12196479
|
|
Platelets [Microparticles]
|
10233897
|
|
Platelets [Microparticles]
|
10233897
|
|
Platelets [Microparticles]
|
10233897
|
|
Red blood cells [Microvesicles]
|
7697722
|
|
Synovial fluid [Microvesicles]
|
23185418
|
Experiment description of studies that identified Phosphatidylserine (PS) in exosomes |
| 1
|
| Experiment ID | 131 |
| Identified molecule | Lipid
|
| Identification method | Cytofluorographic analysis Annexin-V-FITC
|
| PubMed ID |
19188015
|
| Organism | Homo sapiens |
| Experiment description | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes |
| Authors | Keller S, Kö AK, Marmé, Runz S, Wolterink S, Koensgen D, Mustea A, Sehouli J, Altevogt P. |
| Journal name |
CL
|
| Publication year | 2009 |
| Sample | Ascites |
| Sample name | Malignant ascites - Ovarian cancer |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Cytofluorographic analysis Annexin V-FITC Western blotting FACS |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 221 |
| Identified molecule | Lipid
|
| Identification method | Immunoaffinity
|
| PubMed ID |
9918520
|
| Organism | Homo sapiens |
| Experiment description | Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity |
| Authors | Mallat Z, Hugel B, Ohan J, Lesèe G, Freyssinet JM, Tedgui A |
| Journal name |
Circulation
|
| Publication year | 1999 |
| Sample | Atherosclerotic plaques |
| Sample name | Atherosclerotic plaques |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Immunohistochemistry Immunoaffinity |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 128 |
| Identified molecule | Lipid
|
| Identification method | HPLC Gas chromatography
|
| PubMed ID |
14965343
|
| Organism | Homo sapiens |
| Experiment description | Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization |
| Authors | Laulagnier K, Motta C, Hamdi S, Roy S, Fauvelle F, Pageaux JF, Kobayashi T, Salles JP, Perret B, Bonnerot C, Record M. |
| Journal name |
BJ
|
| Publication year | 2004 |
| Sample | Dendritic cells |
| Sample name | Bone marrow - Dendritic cells |
| Molecules identified in the study | Lipids |
| Methods used in the study | High performance liquid chromatography Gas chromatography |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 233 |
| Identified molecule | Lipid
|
| Identification method | Thin layer chromatography Cytofluorographic analysis
|
| PubMed ID |
7697722
|
| Organism | Homo sapiens |
| Experiment description | Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells |
| Authors | Fourcade O, Simon MF, Viodé, Rugani N, Leballe F, Ragab A, Fournié, Sarda L, Chap H |
| Journal name |
Cell
|
| Publication year | 1995 |
| Sample | Inflammatory fluid |
| Sample name | Inflammatory fluids - Arthritis |
| Molecules identified in the study | Lipids |
| Methods used in the study | Thin layer chromatography Cytofluorographic analysis |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 1012 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry
|
| PubMed ID |
22711894
|
| Organism | Homo sapiens |
| Experiment description | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. |
| Authors | Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. |
| Journal name |
J Immunol.
|
| Publication year | 2012 |
| Sample | Macrophage |
| Sample name | Monocyte-derived macrophages - uninfected |
| Molecules identified in the study | Protein |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
EV120137: EV-METRIC:17%, 0%
|
|
|
| 6
|
| Experiment ID | 1013 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry
|
| PubMed ID |
22711894
|
| Organism | Homo sapiens |
| Experiment description | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. |
| Authors | Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. |
| Journal name |
J Immunol.
|
| Publication year | 2012 |
| Sample | Macrophage |
| Sample name | Monocyte-derived macrophages - HLA-DR pulldwon microvesicles |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
EV120137: EV-METRIC:17%, 0%
|
|
|
| 7
|
| Experiment ID | 1014 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry
|
| PubMed ID |
22711894
|
| Organism | Homo sapiens |
| Experiment description | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. |
| Authors | Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. |
| Journal name |
J Immunol.
|
| Publication year | 2012 |
| Sample | Macrophage |
| Sample name | Monocyte-derived macrophages - CHMP4/TSG101 pulldown exosomes |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
EV120137: EV-METRIC:17%, 0%
|
|
|
| 8
|
| Experiment ID | 1015 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry
|
| PubMed ID |
22711894
|
| Organism | Homo sapiens |
| Experiment description | Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. |
| Authors | Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. |
| Journal name |
J Immunol.
|
| Publication year | 2012 |
| Sample | Macrophage |
| Sample name | Monocyte-derived macrophages - Myosin B pulldown exosomes |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
EV120137: EV-METRIC:17%, 0%
|
|
|
| 9
|
| Experiment ID | 71 |
| Identified molecule | Lipid
|
| Identification method | Thin layer chromatography
|
| PubMed ID |
19801663
|
| Organism | Homo sapiens |
| Experiment description | Microenvironmental pH is a key factor for exosome traffic in tumor cells. |
| Authors | Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, de Milito A, Coscia C, Iessi E, Logozzi MA, Molinari A, Colone M, Tatti M, Sargiacomo M, Fais S |
| Journal name |
JBC
|
| Publication year | 2009 |
| Sample | Melanoma cells |
| Sample name | Mel1 |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Western blotting Thin layer chromatography |
| EV-TRACK |
-
|
|
|
| 10
|
| Experiment ID | 132 |
| Identified molecule | Lipid
|
| Identification method | Cytofluorographic analysis Annexin-V-FITC
|
| PubMed ID |
19188015
|
| Organism | Homo sapiens |
| Experiment description | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes |
| Authors | Keller S, Kö AK, Marmé, Runz S, Wolterink S, Koensgen D, Mustea A, Sehouli J, Altevogt P. |
| Journal name |
CL
|
| Publication year | 2009 |
| Sample | Ovarian cancer cells |
| Sample name | OVMz |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Cytofluorographic analysis Annexin V-FITC FACS |
| EV-TRACK |
-
|
|
|
| 11
|
| Experiment ID | 133 |
| Identified molecule | Lipid
|
| Identification method | Cytofluorographic analysis Annexin-V-FITC
|
| PubMed ID |
19188015
|
| Organism | Homo sapiens |
| Experiment description | Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes |
| Authors | Keller S, Kö AK, Marmé, Runz S, Wolterink S, Koensgen D, Mustea A, Sehouli J, Altevogt P. |
| Journal name |
CL
|
| Publication year | 2009 |
| Sample | Ovarian cancer cells |
| Sample name | SKOV3ip |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | Cytofluorographic analysis Annexin V-FITC FACS |
| EV-TRACK |
-
|
|
|
| 12
|
| Experiment ID | 261 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
12805058
|
| Organism | Homo sapiens |
| Experiment description | Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes |
| Authors | Shet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP. |
| Journal name |
Blood
|
| Publication year | 2003 |
| Sample | Plasma |
| Sample name | Plasma - Sickle cell patients - Crisis |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 13
|
| Experiment ID | 250 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
9396452
|
| Organism | Homo sapiens |
| Experiment description | Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant |
| Authors | Nieuwland R, Berckmans RJ, Rotteveel-Eijkman RC, Maquelin KN, Roozendaal KJ, Jansen PG, ten Have K, Eijsman L, Hack CE, Sturk A |
| Journal name |
Circulation
|
| Publication year | 1997 |
| Sample | Plasma |
| Sample name | Plasma - Systemic blood - Cardiopulmonary bypass patients |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 14
|
| Experiment ID | 251 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
9396452
|
| Organism | Homo sapiens |
| Experiment description | Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant |
| Authors | Nieuwland R, Berckmans RJ, Rotteveel-Eijkman RC, Maquelin KN, Roozendaal KJ, Jansen PG, ten Have K, Eijsman L, Hack CE, Sturk A |
| Journal name |
Circulation
|
| Publication year | 1997 |
| Sample | Plasma |
| Sample name | Plasma - Pericardial blood - Cardiopulmonary bypass patients |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 15
|
| Experiment ID | 262 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
12805058
|
| Organism | Homo sapiens |
| Experiment description | Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes |
| Authors | Shet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP. |
| Journal name |
Blood
|
| Publication year | 2003 |
| Sample | Plasma |
| Sample name | Plasma - Sickle cell patients - Steady state |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 16
|
| Experiment ID | 288 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
12196479
|
| Organism | Homo sapiens |
| Experiment description | Type 1 and type 2 diabetic patients display different patterns of cellular microparticles |
| Authors | Sabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F |
| Journal name |
Diabetes
|
| Publication year | 2002 |
| Sample | Plasma |
| Sample name | Plasma - Healthy donors |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 17
|
| Experiment ID | 289 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
12196479
|
| Organism | Homo sapiens |
| Experiment description | Type 1 and type 2 diabetic patients display different patterns of cellular microparticles |
| Authors | Sabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F |
| Journal name |
Diabetes
|
| Publication year | 2002 |
| Sample | Plasma |
| Sample name | Plasma - Type 1 diabetes |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 18
|
| Experiment ID | 290 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
12196479
|
| Organism | Homo sapiens |
| Experiment description | Type 1 and type 2 diabetic patients display different patterns of cellular microparticles |
| Authors | Sabatier F, Darmon P, Hugel B, Combes V, Sanmarco M, Velut JG, Arnoux D, Charpiot P, Freyssinet JM, Oliver C, Sampol J, Dignat-George F |
| Journal name |
Diabetes
|
| Publication year | 2002 |
| Sample | Plasma |
| Sample name | Plasma - Type 2 diabetes |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS Annexin V-FITC |
| EV-TRACK |
-
|
|
|
| 19
|
| Experiment ID | 278 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
10233897
|
| Organism | Homo sapiens |
| Experiment description | Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia |
| Authors | Hugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML |
| Journal name |
Blood
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets - Normal |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS |
| EV-TRACK |
-
|
|
|
| 20
|
| Experiment ID | 240 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
10233897
|
| Organism | Homo sapiens |
| Experiment description | Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia |
| Authors | Hugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML |
| Journal name |
Blood
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets - Paroxysmal nocturnal hemoglobinuria patients |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS |
| EV-TRACK |
-
|
|
|
| 21
|
| Experiment ID | 295 |
| Identified molecule | Lipid
|
| Identification method | Annexin V-FITC
|
| PubMed ID |
10233897
|
| Organism | Homo sapiens |
| Experiment description | Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia |
| Authors | Hugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML |
| Journal name |
Blood
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets - Aplastic anemia patients |
| Molecules identified in the study | Lipids |
| Methods used in the study | FACS |
| EV-TRACK |
-
|
|
|
| 22
|
| Experiment ID | 232 |
| Identified molecule | Lipid
|
| Identification method | Thin layer chromatography Cytofluorographic analysis
|
| PubMed ID |
7697722
|
| Organism | Homo sapiens |
| Experiment description | Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells |
| Authors | Fourcade O, Simon MF, Viodé, Rugani N, Leballe F, Ragab A, Fournié, Sarda L, Chap H |
| Journal name |
Cell
|
| Publication year | 1995 |
| Sample | Red blood cells |
| Sample name | Erythrocyte |
| Molecules identified in the study | Lipids |
| Methods used in the study | Thin layer chromatography Cytofluorographic analysis |
| EV-TRACK |
-
|
|
|
| 23
|
| Experiment ID | 1011 |
| Identified molecule | Lipid
|
| Identification method | Mass spectrometry
|
| PubMed ID |
23185418
|
| Organism | Homo sapiens |
| Experiment description | Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. |
| Authors | Gyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI. |
| Journal name |
PLoS One.
|
| Publication year | 2012 |
| Sample | Synovial fluid |
| Sample name | synovial fluid - patient with juvenile idiopathic arthritis (JIA) |
| Molecules identified in the study | Protein |
| Methods used in the study | Mass spectrometry FACS |
| EV-TRACK |
EV120104: EV-METRIC:29%
|
|
|