Gene description for PDCD6IP
Gene name programmed cell death 6 interacting protein
Gene symbol PDCD6IP
Other names/aliases AIP1
ALIX
DRIP4
HP95
MCPH29
Species Homo sapiens
 Experiment description of studies that identified PDCD6IP in Saliva

1
Experiment ID66
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
Western blotting
PubMed ID 19199708   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
AuthorsGonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year2009
SampleSaliva
Sample nameSaliva
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
Immunoelectron microscopy
EV-TRACK -

2
Experiment ID1155
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21212511   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of two types of exosomes in human whole saliva.
AuthorsOgawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R.
Journal name Biol Pharm Bull
Publication year2011
SampleSaliva
Sample nameExosome I
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV110053: EV-METRIC:11%

3
Experiment ID1156
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21212511   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of two types of exosomes in human whole saliva.
AuthorsOgawa Y, Miura Y, Harazono A, Kanai-Azuma M, Akimoto Y, Kawakami H, Yamaguchi T, Toda T, Endo T, Tsubuki M, Yanoshita R.
Journal name Biol Pharm Bull
Publication year2011
SampleSaliva
Sample nameExosome II
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV110053: EV-METRIC:11%

4
Experiment ID1392
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32939236   
OrganismHomo sapiens
Experiment descriptionSalivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection
AuthorsConzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA.
Journal name J Extracell Vesicles
Publication year2020
SampleSaliva
Sample nameSaliva - pooled (13.1 µg protein)
Isolation/purification methodsDifferential centrifugation
Tangential flow filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID1393
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32939236   
OrganismHomo sapiens
Experiment descriptionSalivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection
AuthorsConzelmann C, Groß R, Zou M, Krüger F, Görgens A, Gustafsson MO, El Andaloussi S, Münch J, Müller JA.
Journal name J Extracell Vesicles
Publication year2020
SampleSaliva
Sample nameSaliva - pooled (7.1 µg protein)
Isolation/purification methodsDifferential centrifugation
Tangential flow filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID2772
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33432243   
OrganismHomo sapiens
Experiment descriptionExosome detection via the ultrafast-isolation system: EXODUS
AuthorsChen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F.
Journal name Nat Methods
Publication year2021
SampleSaliva
Sample nameSaliva
Isolation/purification methodsFiltration
Exosome detection via ultrafast-isolation system (EXODUS)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID2773
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33432243   
OrganismHomo sapiens
Experiment descriptionExosome detection via the ultrafast-isolation system: EXODUS
AuthorsChen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F.
Journal name Nat Methods
Publication year2021
SampleSaliva
Sample nameSaliva
Isolation/purification methodsFiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID2774
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33432243   
OrganismHomo sapiens
Experiment descriptionExosome detection via the ultrafast-isolation system: EXODUS
AuthorsChen Y, Zhu Q, Cheng L, Wang Y, Li M, Yang Q, Hu L, Lou D, Li J, Dong X, Lee LP, Liu F.
Journal name Nat Methods
Publication year2021
SampleSaliva
Sample nameSaliva
Isolation/purification methodsFiltration
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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