Gene description for Cd63
Gene name CD63 antigen
Gene symbol Cd63
Other names/aliases ME491
Tspan30
Species Mus musculus
 Experiment description of studies that identified Cd63 in Hepatocytes

1
Experiment ID36
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 19367702   
OrganismMus musculus
Experiment descriptionCharacterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
AuthorsConde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year2008
SampleHepatocytes
Sample nameMLP-29
Isolation/purification methodsDifferential centrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID1470
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID1471
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID1472
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6 - Fraction 2
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID1473
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6 - Fraction 3
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID1480
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - WT C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA array
EV-TRACK -

7
Experiment ID1481
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - Liver-specific Ggpps-/- C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA array
EV-TRACK -

8
Experiment ID1482
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - WT C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA array
EV-TRACK -

9
Experiment ID1483
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 32024826   
OrganismMus musculus
Experiment descriptionLiver governs adipose remodelling via extracellular vesicles in response to lipid overload
AuthorsZhao Y, Zhao MF, Jiang S, Wu J, Liu J, Yuan XW, Shen D, Zhang JZ, Zhou N, He J, Fang L, Sun XT, Xue B, Li CJ.
Journal name Nat Commun
Publication year2020
SampleHepatocytes
Sample namePrimary hepatocytes - Liver-specific Ggpps-/- C57BL/6
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA array
EV-TRACK -

10
Experiment ID2442
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34489604   
OrganismMus musculus
Experiment descriptionHepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
AuthorsJi Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM.
Journal name Nat Metab
Publication year2021
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6
Isolation/purification methodsCentrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

11
Experiment ID2443
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34489604   
OrganismMus musculus
Experiment descriptionHepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
AuthorsJi Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM.
Journal name Nat Metab
Publication year2021
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6
Isolation/purification methodsCentrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

12
Experiment ID2444
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34489604   
OrganismMus musculus
Experiment descriptionHepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
AuthorsJi Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM.
Journal name Nat Metab
Publication year2021
SampleHepatocytes
Sample namePrimary hepatocytes - C57BL/6
Isolation/purification methodsCentrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

13
Experiment ID2445
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34489604   
OrganismMus musculus
Experiment descriptionHepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
AuthorsJi Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM.
Journal name Nat Metab
Publication year2021
SampleHepatocytes
Sample namePrimary hepatocytes - hepatocyte-specific Cas9 transgenic C57BL/6
Isolation/purification methodsCentrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

14
Experiment ID2446
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34489604   
OrganismMus musculus
Experiment descriptionHepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
AuthorsJi Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM.
Journal name Nat Metab
Publication year2021
SampleHepatocytes
Sample namePrimary hepatocytes - hepatocyte-specific Cas9 transgenic C57BL/6
Isolation/purification methodsCentrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

<