Gene description for Serpina1b
Gene name serine (or cysteine) preptidase inhibitor, clade A, member 1B
Gene symbol Serpina1b
Other names/aliases D12Ucla2
Dom2
PI2
Spi1-2
Species Mus musculus
 Experiment description of studies that identified Serpina1b in Faeces

1
Experiment ID1323
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 33431899   
OrganismMus musculus
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameIntestinal epithelial cells - C57BL/6
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
miRNA
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
EV-TRACK -

2
Experiment ID1324
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 33431899   
OrganismMus musculus
Experiment descriptionHigh-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
AuthorsKumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG.
Journal name Nat Commun
Publication year2021
SampleFaeces
Sample nameIntestinal epithelial cells - C57BL/6
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
miRNA
Methods used in the studyWestern blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
EV-TRACK -

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