Gene description for ALB
Gene name albumin
Gene symbol ALB
Other names/aliases FDAHT
HSA
PRO0883
PRO0903
PRO1341
Species Homo sapiens
 Experiment description of studies that identified ALB in Plasma

1
Experiment ID44
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 19028452   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
AuthorsLooze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ
Journal name BBRC
Publication year2009
SamplePlasma
Sample namePlasma
Isolation/purification methodsFiltration
Size exclusion chromatography
Sucrose density gradient
Flotation density1.15-1.16 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
Western blotting
Immunoelectron microscopy
EV-TRACK -

2
Experiment ID353
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry [Orbitrap Velos]
PubMed ID 24115447   
OrganismHomo sapiens
Experiment descriptionComparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma
AuthorsMathivanan,S.
Journal name Proteomics
Publication year2013
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [Orbitrap Velos]
Western blotting
EV-TRACK EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%

3
Experiment ID354
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry [Orbitrap Velos]
PubMed ID 24115447   
OrganismHomo sapiens
Experiment descriptionComparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma
AuthorsMathivanan,S.
Journal name Proteomics
Publication year2013
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [Orbitrap Velos]
Western blotting
EV-TRACK EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%

4
Experiment ID355
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry [Orbitrap Velos]
PubMed ID 24115447   
OrganismHomo sapiens
Experiment descriptionComparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma
AuthorsMathivanan,S.
Journal name Proteomics
Publication year2013
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Immunoaffinity (EpCAM)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [Orbitrap Velos]
Western blotting
EV-TRACK EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%

5
Experiment ID443
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22329422   
OrganismHomo sapiens
Experiment descriptionQuantitative proteome profiling of normal human circulating microparticles.
AuthorsØstergaard O, Nielsen CT, Iversen LV, Jacobsen S, Tanassi JT, Heegaard NH.
Journal name J Proteome Res
Publication year2012
SamplePlasma
Sample nameNormal-Platelet-poor plasma
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

6
Experiment ID454
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22669077   
OrganismHomo sapiens
Experiment descriptionThe proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation.
AuthorsBosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM.
Journal name J Proteomics
Publication year2012
SamplePlasma
Sample nameNormal-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

7
Experiment ID473
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23056467   
OrganismHomo sapiens
Experiment descriptionCause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.
AuthorsAl Kaabi A, Traupe T, Stutz M, Buchs N, Heller M.
Journal name PLoS One
Publication year2012
SamplePlasma
Sample namePatients of external counterpulsation therapy-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

8
Experiment ID863
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22046311   
OrganismMus musculus
Experiment descriptionExosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections
AuthorsMartin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA.
Journal name PLoS One
Publication year2011
SamplePlasma
Sample namePeripheral blood plasma - P. yoelii 17X infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
Mass spectrometry
EV-TRACK EV110102: EV-METRIC:25%, 25%

9
Experiment ID1075
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25104112   
OrganismHomo sapiens
Experiment descriptionPlacenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.
AuthorsSarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C.
Journal name J Transl Med
Publication year2014
SamplePlasma
Sample nameFresh plasma- healthy women
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.12-1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140094: EV-METRIC:56%

10
Experiment ID1076
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25104112   
OrganismHomo sapiens
Experiment descriptionPlacenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.
AuthorsSarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C.
Journal name J Transl Med
Publication year2014
SamplePlasma
Sample nameStored plamsa(freeze/thaw) plasma- healthy women
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Flotation density1.12-1.19 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140094: EV-METRIC:56%

11
Experiment ID1223
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 1
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

12
Experiment ID1224
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 2
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

13
Experiment ID1225
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 3
Isolation/purification methodsExo-spin
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

14
Experiment ID1226
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 1 fr7+8
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

15
Experiment ID1227
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 1 fr9+10
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

16
Experiment ID1228
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar fr11
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

17
Experiment ID1229
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26154623   
OrganismHomo sapiens
Experiment descriptionSize-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals
Authorsde Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA.
Journal name J Extracell Vesicles.
Publication year2015
SamplePlasma
Sample nameDonar 3 fr8
Isolation/purification methodsSize exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150034: EV-METRIC:17%, 57%

18
Experiment ID2317
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles/Exosomes
MISEVEVs
Identification method Western blotting
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameNon-smokers
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

19
Experiment ID2318
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles/Exosomes
MISEVEVs
Identification method Western blotting
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameSmokers
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

20
Experiment ID2319
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles/Exosomes
MISEVEVs
Identification method Western blotting
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameCOPD patients
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -

21
Experiment ID1727
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 9
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
ELISA
EV-TRACK -

22
Experiment ID1728
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 10
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

23
Experiment ID1729
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 11
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

24
Experiment ID1730
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 12
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

25
Experiment ID1731
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 13
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

26
Experiment ID1732
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 14
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

27
Experiment ID1733
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 15
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

28
Experiment ID1734
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 16
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

29
Experiment ID1735
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 17
Isolation/purification methodsCentrifugal filtration
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

30
Experiment ID1747
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 1
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.012 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

31
Experiment ID1748
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 2
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.028 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

32
Experiment ID1749
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 3
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.045 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

33
Experiment ID1750
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 4
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.056 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

34
Experiment ID1751
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 5
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.065 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

35
Experiment ID1752
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 6
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.076 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

36
Experiment ID1753
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 7
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.097 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

37
Experiment ID1754
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 8
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.113 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

38
Experiment ID1755
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 9
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.138 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

39
Experiment ID1756
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 10
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.193 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

40
Experiment ID1757
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method SIMOA
PubMed ID 34092791   
OrganismHomo sapiens
Experiment descriptionL1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma
AuthorsNorman M, Ter-Ovanesyan D, Trieu W, Lazarovits R, Kowal EJK, Lee JH, Chen-Plotkin AS, Regev A, Church GM, Walt DR.
Journal name Nat Methods
Publication year2021
SamplePlasma
Sample nameFraction 11
Isolation/purification methodsCentrifugal filtration
OptiPrep density gradient centrifugation
Flotation density1.219 g/mL
Molecules identified in the studyProtein
Methods used in the studySIMOA
EV-TRACK -

41
Experiment ID2848
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-001 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

42
Experiment ID2848
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-001 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

43
Experiment ID2849
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-004 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

44
Experiment ID2849
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-004 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

45
Experiment ID2850
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-012 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

46
Experiment ID2850
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-012 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

47
Experiment ID2851
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-024 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

48
Experiment ID2851
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-024 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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