Gene description for GC |
Gene name |
GC vitamin D binding protein |
Gene symbol |
GC |
Other names/aliases |
DBP DBP-maf DBP/GC GRD3 Gc-MAF GcMAF HEL-S-51 VDB VDBG VDBP |
Species |
Homo sapiens |
Experiment description of studies that identified GC in Plasma |
1
|
Experiment ID | 443 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22329422
|
Organism | Homo sapiens |
Experiment description | Quantitative proteome profiling of normal human circulating microparticles. |
Authors | Østergaard O, Nielsen CT, Iversen LV, Jacobsen S, Tanassi JT, Heegaard NH. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Normal-Platelet-poor plasma |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 473 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23056467
|
Organism | Homo sapiens |
Experiment description | Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. |
Authors | Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Patients of external counterpulsation therapy-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 863 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22046311
|
Organism | Mus musculus |
Experiment description | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections |
Authors | Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA. |
Journal name |
PLoS One
|
Publication year | 2011 |
Sample | Plasma |
Sample name | Peripheral blood plasma - P. yoelii 17X infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS Mass spectrometry |
EV-TRACK |
EV110102: EV-METRIC:25%, 25%
|
|
|
4
|
Experiment ID | 1224 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
26154623
|
Organism | Homo sapiens |
Experiment description | Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals |
Authors | de Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2015 |
Sample | Plasma |
Sample name | Donar 2 |
Isolation/purification methods | Exo-spin |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150034: EV-METRIC:17%, 57%
|
|
|
5
|
Experiment ID | 1225 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
26154623
|
Organism | Homo sapiens |
Experiment description | Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals |
Authors | de Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2015 |
Sample | Plasma |
Sample name | Donar 3 |
Isolation/purification methods | Exo-spin |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150034: EV-METRIC:17%, 57%
|
|
|
6
|
Experiment ID | 1226 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
26154623
|
Organism | Homo sapiens |
Experiment description | Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals |
Authors | de Menezes-Neto A, Sá MJ, Lozano-Ramos I, Segui-Barber J, Martin-Jaular L, Ullate JM, Fernandez-Becerra C, BorráFE, Del Portillo HA. |
Journal name |
J Extracell Vesicles.
|
Publication year | 2015 |
Sample | Plasma |
Sample name | Donar 1 fr7+8 |
Isolation/purification methods | Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150034: EV-METRIC:17%, 57%
|
|
|
7
|
Experiment ID | 2267 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
36624553
|
Organism | Homo sapiens |
Experiment description | Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles |
Authors | Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. |
Journal name |
Proteomics
|
Publication year | 2023 |
Sample | Plasma |
Sample name | Plasma |
Isolation/purification methods | Filtration Size exclusion chromatography Centrifugal ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 2268 |
Identified molecule | Protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
36624553
|
Organism | Homo sapiens |
Experiment description | Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles |
Authors | Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. |
Journal name |
Proteomics
|
Publication year | 2023 |
Sample | Plasma |
Sample name | Plasma - Ion exchange adsorption 12.5 mg |
Isolation/purification methods | Filtration Size exclusion chromatography Ion exchange adsorption Centrifugation Centrifugal ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 2269 |
Identified molecule | Protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
36624553
|
Organism | Homo sapiens |
Experiment description | Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles |
Authors | Wang Y, Zhang Y, Li Z, Wei S, Chi X, Yan X, Lv H, Zhao L, Zhao L. |
Journal name |
Proteomics
|
Publication year | 2023 |
Sample | Plasma |
Sample name | Plasma - Ion exchange adsorption 25 mg |
Isolation/purification methods | Filtration Size exclusion chromatography Ion exchange adsorption Centrifugation Centrifugal ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 2329 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
32487994
|
Organism | Homo sapiens |
Experiment description | Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence |
Authors | Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Plasma |
Sample name | Healthy donors |
Isolation/purification methods | Centrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 2330 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
32487994
|
Organism | Homo sapiens |
Experiment description | Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence |
Authors | Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Plasma |
Sample name | Plasmodium vivax (Malaria) patients |
Isolation/purification methods | Centrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 2848 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | NWL-001 - Lung cancer patient |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 2849 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | NWL-004 - Lung cancer patient |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 2850 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | CSB-012 - COVID-19 patient - convalescent phase |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
15
|
Experiment ID | 2851 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | CSB-024 - COVID-19 patient - convalescent phase |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|