Gene description for GP1BA
Gene name glycoprotein Ib platelet subunit alpha
Gene symbol GP1BA
Other names/aliases BDPLT1
BDPLT3
BSS
CD42B
CD42b-alpha
DBPLT3
GP1B
GPIbA
GPIbalpha
VWDP
Species Homo sapiens
 Experiment description of studies that identified GP1BA in Platelets

1
Experiment ID278
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 10233897   
OrganismHomo sapiens
Experiment descriptionElevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia
AuthorsHugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML
Journal name Blood
Publication year1999
SamplePlatelets
Sample namePlatelets - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
EV-TRACK -

2
Experiment ID240
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 10233897   
OrganismHomo sapiens
Experiment descriptionElevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia
AuthorsHugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML
Journal name Blood
Publication year1999
SamplePlatelets
Sample namePlatelets - Paroxysmal nocturnal hemoglobinuria patients
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
EV-TRACK -

3
Experiment ID294
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Western blotting
PubMed ID 2071604   
OrganismHomo sapiens
Experiment descriptionEvidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets
AuthorsFox JE, Austin CD, Reynolds CC, Steffen PK
Journal name J Biol Chem
Publication year1991
SamplePlatelets
Sample namePlatelets
Isolation/purification methodsDifferential centrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID369
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 16212402   
OrganismHomo sapiens
Experiment descriptionThe platelet microparticle proteome.
AuthorsGarcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF.
Journal name J Proteome Res
Publication year2005
SamplePlatelets
Sample nameNormal donors-Platelets
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

5
Experiment ID520
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23601281   
OrganismHomo sapiens
Experiment descriptionProteomic characterization of human platelet-derived microparticles.
AuthorsCapriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A.
Journal name Anal Chim Acta
Publication year2013
SamplePlatelets
Sample namePlatelets purifird from blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

6
Experiment ID1344
Identified moleculeprotein
Extracellular vesicle typePlatelet-derived microparticles
MISEVEV-like nanoparticles
Identification method Flow cytometry
PubMed ID 33009394   
OrganismHomo sapiens
Experiment descriptionPlatelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p
AuthorsQu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X.
Journal name Nat Commun
Publication year2020
SamplePlatelets
Sample namePlatelets derived from umbilical cord blood
Isolation/purification methodsFicoll-Hypaque density gradient centrifugation
Differential centrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyFlow cytometry
Western blotting
qPCR
EV-TRACK -

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