Gene description for GP1BA |
| Gene name |
glycoprotein Ib platelet subunit alpha |
| Gene symbol |
GP1BA |
| Other names/aliases |
BDPLT1 BDPLT3 BSS CD42B CD42b-alpha DBPLT3 GP1B GPIbA GPIbalpha VWDP |
| Species |
Homo sapiens |
Experiment description of studies that identified GP1BA in Platelets |
| 1
|
| Experiment ID | 278 |
| Identified molecule | protein
|
| Extracellular vesicle type | Microparticles |
| MISEV | EVs |
| Identification method | FACS
|
| PubMed ID |
10233897
|
| Organism | Homo sapiens |
| Experiment description | Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia |
| Authors | Hugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML |
| Journal name |
Blood
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets - Normal |
| Isolation/purification methods | Differential centrifugation FACS |
| Flotation density | - |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 240 |
| Identified molecule | protein
|
| Extracellular vesicle type | Microparticles |
| MISEV | EVs |
| Identification method | FACS
|
| PubMed ID |
10233897
|
| Organism | Homo sapiens |
| Experiment description | Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia |
| Authors | Hugel B, Socié, Vu T, Toti F, Gluckman E, Freyssinet JM, Scrobohaci ML |
| Journal name |
Blood
|
| Publication year | 1999 |
| Sample | Platelets |
| Sample name | Platelets - Paroxysmal nocturnal hemoglobinuria patients |
| Isolation/purification methods | Differential centrifugation FACS |
| Flotation density | - |
| Molecules identified in the study | Protein Lipids |
| Methods used in the study | FACS |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 294 |
| Identified molecule | protein
|
| Extracellular vesicle type | Microvesicles |
| MISEV | EVs |
| Identification method | Western blotting
|
| PubMed ID |
2071604
|
| Organism | Homo sapiens |
| Experiment description | Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets |
| Authors | Fox JE, Austin CD, Reynolds CC, Steffen PK |
| Journal name |
J Biol Chem
|
| Publication year | 1991 |
| Sample | Platelets |
| Sample name | Platelets |
| Isolation/purification methods | Differential centrifugation Filtration |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Western blotting |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 369 |
| Identified molecule | protein
|
| Extracellular vesicle type | Microparticles |
| MISEV | EVs |
| Identification method | Mass spectrometry
|
| PubMed ID |
16212402
|
| Organism | Homo sapiens |
| Experiment description | The platelet microparticle proteome. |
| Authors | Garcia BA, Smalley DM, Cho H, Shabanowitz J, Ley K, Hunt DF. |
| Journal name |
J Proteome Res
|
| Publication year | 2005 |
| Sample | Platelets |
| Sample name | Normal donors-Platelets |
| Isolation/purification methods | - |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 520 |
| Identified molecule | protein
|
| Extracellular vesicle type | Microparticles |
| MISEV | EVs |
| Identification method | Mass spectrometry
|
| PubMed ID |
23601281
|
| Organism | Homo sapiens |
| Experiment description | Proteomic characterization of human platelet-derived microparticles. |
| Authors | Capriotti AL, Caruso G, Cavaliere C, Piovesana S, Samperi R, Laganà A. |
| Journal name |
Anal Chim Acta
|
| Publication year | 2013 |
| Sample | Platelets |
| Sample name | Platelets purifird from blood |
| Isolation/purification methods | - |
| Flotation density | - |
| Molecules identified in the study | Protein |
| Methods used in the study | Mass spectrometry |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 1344 |
| Identified molecule | protein
|
| Extracellular vesicle type | Platelet-derived microparticles |
| MISEV | EV-like nanoparticles |
| Identification method | Flow cytometry
|
| PubMed ID |
33009394
|
| Organism | Homo sapiens |
| Experiment description | Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p |
| Authors | Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. |
| Journal name |
Nat Commun
|
| Publication year | 2020 |
| Sample | Platelets |
| Sample name | Platelets derived from umbilical cord blood |
| Isolation/purification methods | Ficoll-Hypaque density gradient centrifugation Differential centrifugation Filtration |
| Flotation density | - |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Flow cytometry Western blotting qPCR |
| EV-TRACK |
-
|
|
|