Gene description for GRB2
Gene name	growth factor receptor bound protein 2
Gene symbol	GRB2
Other names/aliases	ASH EGFRBP-GRB2 Grb3-3 MST084 MSTP084 NCKAP2
Species	Homo sapiens
Experiment description of studies that identified GRB2 in Melanoma cells
1 Experiment ID 621 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-2 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
2 Experiment ID 623 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name SK-MEL-5 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
3 Experiment ID 625 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Melanoma cells Sample name UACC-62 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
4 Experiment ID 1627 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 34012515    Organism Homo sapiens Experiment description CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Authors Suárez H, Andreu Z, Mazzeo C, Toribio V, Pérez-Rivera AE, López-Martín S, García-Silva S, Hurtado B, Morato E, Peláez L, Arribas EA, Tolentino-Cortez T, Barreda-Gómez G, Marina AI, Peinado H, Yáñez-Mó M. Journal name J Extracell Vesicles Publication year 2021 Sample Melanoma cells Sample name SK‐MEL‐147 Isolation/purification methods Differential centrifugation Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study LC-MS/MS MALDI-MS Western blotting EV-TRACK -
5 Experiment ID 1628 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 34012515    Organism Homo sapiens Experiment description CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Authors Suárez H, Andreu Z, Mazzeo C, Toribio V, Pérez-Rivera AE, López-Martín S, García-Silva S, Hurtado B, Morato E, Peláez L, Arribas EA, Tolentino-Cortez T, Barreda-Gómez G, Marina AI, Peinado H, Yáñez-Mó M. Journal name J Extracell Vesicles Publication year 2021 Sample Melanoma cells Sample name SK‐MEL‐147 Isolation/purification methods Differential centrifugation Centrifugal ultrafiltration Size exclusion chromatography Flotation density - Molecules identified in the study Protein Lipid Methods used in the study LC-MS/MS MALDI-MS Western blotting EV-TRACK -