Gene description for ANXA2
Gene name	annexin A2
Gene symbol	ANXA2
Other names/aliases	ANX2 ANX2L4 CAL1H HEL-S-270 LIP2 LPC2 LPC2D P36 PAP-IV
Species	Homo sapiens
Experiment description of studies that identified ANXA2 in Breast cancer cells
1 Experiment ID 65 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 19415654    Organism Homo sapiens Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Authors Staubach S, Razawi H, Hanisch FG. Journal name PROTEOMICS Publication year 2009 Sample Breast cancer cells Sample name MCF-7 Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [MALDI TOF] Western blotting EV-TRACK -
2 Experiment ID 575 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name BT549 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
3 Experiment ID 577 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
4 Experiment ID 886 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25102470    Organism Homo sapiens Experiment description Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Authors Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ. Journal name Biochim Biophys Acta Publication year 2014 Sample Breast cancer cells Sample name MCF-7 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.10-1.20 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV140013: EV-METRIC:56%
5 Experiment ID 1018 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 22399603    Organism Homo sapiens Experiment description Proteomic analysis of exosome-like vesicles derived from breast cancer cells. Authors Palazzolo G, Albanese NN, DI Cara G, Gygax D, Vittorelli ML, Pucci-Minafra I. Journal name Anticancer Res Publication year 2012 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV120036: EV-METRIC:44%
6 Experiment ID 1254 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 24468161    Organism Homo sapiens Experiment description Molecular characterization of exosome-like vesicles from breast cancer cells. Authors Kruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. Journal name BMC Cancer. Publication year 2014 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Microarray RT-PCR Western blotting EV-TRACK EV140357: EV-METRIC:22%
7 Experiment ID 1664 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MCF7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -
8 Experiment ID 1666 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -
9 Experiment ID 1678 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
10 Experiment ID 1679 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
11 Experiment ID 1758 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry Western blotting EV-TRACK -
12 Experiment ID 1758 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry Western blotting EV-TRACK -
13 Experiment ID 1758 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry Western blotting EV-TRACK -
14 Experiment ID 1758 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry Western blotting EV-TRACK -
15 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
16 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
17 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
18 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
19 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
20 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
21 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
22 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
23 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
24 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
25 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
26 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
27 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
28 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
29 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
30 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
31 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
32 Experiment ID 1759 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
33 Experiment ID 1760 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
34 Experiment ID 1760 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
35 Experiment ID 1760 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
36 Experiment ID 1760 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
37 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
38 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
39 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
40 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
41 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
42 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
43 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
44 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
45 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
46 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
47 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
48 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
49 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
50 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
51 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
52 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
53 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
54 Experiment ID 1761 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35918900    Organism Homo sapiens Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Authors Bauzá-Martinez J, Armony G, Pronker MF, Wu W. Journal name J Extracell Vesicles Publication year 2022 Sample Breast cancer cells Sample name LM2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectometry EV-TRACK -
55 Experiment ID 1963 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35915084    Organism Homo sapiens Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
56 Experiment ID 2867 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
57 Experiment ID 2870 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 30918259    Organism Homo sapiens Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Authors Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. Journal name Nat Commun Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry EV-TRACK -
58 Experiment ID 3350 Identified molecule protein Extracellular vesicle type Supermeres MISEV EV-like nanoparticles Identification method Mass spectrometry PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry ELISA EV-TRACK -