Gene description for HSP90AA1
Gene name	heat shock protein 90 alpha family class A member 1
Gene symbol	HSP90AA1
Other names/aliases	EL52 HEL-S-65p HSP86 HSP89A HSP90A HSP90N HSPC1 HSPCA HSPCAL1 HSPCAL4 HSPN Hsp103 Hsp89 Hsp90 LAP-2 LAP2
Species	Homo sapiens
Experiment description of studies that identified HSP90AA1 in Macrophage
1 Experiment ID 1014 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22711894    Organism Homo sapiens Experiment description Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Authors Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. Journal name J Immunol. Publication year 2012 Sample Macrophage Sample name Monocyte-derived macrophages - CHMP4/TSG101 pulldown exosomes Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipids Methods used in the study Mass spectrometry EV-TRACK EV120137: EV-METRIC:17%, 0%
2 Experiment ID 1015 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22711894    Organism Homo sapiens Experiment description Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Authors Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. Journal name J Immunol. Publication year 2012 Sample Macrophage Sample name Monocyte-derived macrophages - Myosin B pulldown exosomes Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipids Methods used in the study Mass spectrometry EV-TRACK EV120137: EV-METRIC:17%, 0%
3 Experiment ID 1017 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22711894    Organism Homo sapiens Experiment description Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Authors Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. Journal name J Immunol. Publication year 2012 Sample Macrophage Sample name Monocyte-derived macrophages - Vinculin/Talin pulldown exosomes Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipids Methods used in the study Mass spectrometry EV-TRACK EV120137: EV-METRIC:17%, 0%
4 Experiment ID 669 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 29953960    Organism Homo sapiens Experiment description Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Authors Singhto N, Thongboonkerd V. Journal name J Proteomics Publication year 2018 Sample Macrophage Sample name U937- Human monocytic cell line differentiated to macrophages (Control) Isolation/purification methods Microfiltration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 670 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 29953960    Organism Homo sapiens Experiment description Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Authors Singhto N, Thongboonkerd V. Journal name J Proteomics Publication year 2018 Sample Macrophage Sample name U937- Human monocytic cell line differentiated to macrophages (COM treated) Isolation/purification methods Microfiltration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -