Gene description for ILK
Gene name	integrin linked kinase
Gene symbol	ILK
Other names/aliases	HEL-S-28 ILK-1 ILK-2 P59 p59ILK
Species	Homo sapiens
Experiment description of studies that identified ILK in Prostate cancer cells
1 Experiment ID 633 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name DU145 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
2 Experiment ID 634 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry [LTQ] PubMed ID 27894104    Organism Homo sapiens Experiment description Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Authors Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. Journal name Oncotarget Publication year 2016 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Polymer-based precipitation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] EV-TRACK -
3 Experiment ID 963 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25844599    Organism Homo sapiens Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T. Journal name Oncotarget Publication year 2015 Sample Prostate cancer cells Sample name DU145 Tax-Sen Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV150027: EV-METRIC:11%, 56%
4 Experiment ID 1261 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24371517    Organism Homo sapiens Experiment description Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Authors Bijnsdorp IV, Geldof AA, Lavaei M, Piersma SR, van Moorselaar RJ, Jimenez CR. Journal name J Extracell Vesicles. Publication year 2013 Sample Prostate cancer cells Sample name PC3 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK EV130168: EV-METRIC:11%, 11%
5 Experiment ID 1122 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 24347249    Organism Homo sapiens Experiment description Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Authors Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. Journal name Mol Carcinog Publication year 2015 Sample Prostate cancer cells Sample name LNCaP- Normoxic Isolation/purification methods Differential centrifugation Ultracentrifugation ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK EV140124: EV-METRIC:43%, 25%
6 Experiment ID 1123 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 24347249    Organism Homo sapiens Experiment description Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Authors Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. Journal name Mol Carcinog Publication year 2015 Sample Prostate cancer cells Sample name LNCaP- Hypoxic Isolation/purification methods Differential centrifugation Ultracentrifugation ExoQuick Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK EV140124: EV-METRIC:43%, 25%