Gene description for ITGA2B
Gene name integrin subunit alpha 2b
Gene symbol ITGA2B
Other names/aliases BDPLT16
BDPLT2
CD41
CD41B
GP2B
GPIIb
GT
GT1
GTA
HPA3
PPP1R93
Species Homo sapiens
 Experiment description of studies that identified ITGA2B in Serum

1
Experiment ID228
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Antibody based methods
PubMed ID 2942561   
OrganismHomo sapiens
Experiment descriptionPlatelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery
AuthorsGeorge JN, Pickett EB, Saucerman S, McEver RP, Kunicki TJ, Kieffer N, Newman PJ
Journal name J Clin Invest
Publication year1986
SampleSerum
Sample nameSerum - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyAntibody based methods
EV-TRACK -

2
Experiment ID1244
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method ELISA
PubMed ID 25167841   
OrganismHomo sapiens
Experiment descriptionAntibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
AuthorsUeda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H.
Journal name Sci Rep.
Publication year2014
SampleSerum
Sample name Normal controls
Isolation/purification methodsCD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140406: EV-METRIC:17%

3
Experiment ID1245
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method ELISA
PubMed ID 25167841   
OrganismHomo sapiens
Experiment descriptionAntibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
AuthorsUeda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H.
Journal name Sci Rep.
Publication year2014
SampleSerum
Sample nameInterstitial pneumonia patients
Isolation/purification methodsCD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140406: EV-METRIC:17%

4
Experiment ID1246
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method ELISA
PubMed ID 25167841   
OrganismHomo sapiens
Experiment descriptionAntibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
AuthorsUeda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H.
Journal name Sci Rep.
Publication year2014
SampleSerum
Sample nameLung adenocarcinoma patients
Isolation/purification methodsCD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140406: EV-METRIC:17%

5
Experiment ID1247
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method ELISA
PubMed ID 25167841   
OrganismHomo sapiens
Experiment descriptionAntibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
AuthorsUeda K, Ishikawa N, Tatsuguchi A, Saichi N, Fujii R, Nakagawa H.
Journal name Sci Rep.
Publication year2014
SampleSerum
Sample nameLung squamous cell carcinoma patients
Isolation/purification methodsCD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140406: EV-METRIC:17%

6
Experiment ID2007
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameHealthy donors
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

7
Experiment ID2008
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameSevere COVID-19 patients
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

8
Experiment ID2009
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Flow cytometry
PubMed ID 35979935   
OrganismHomo sapiens
Experiment descriptionSerum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients
AuthorsTertel T, Tomić S, Đokić J, Radojević D, Stevanović D, Ilić N, Giebel B, Kosanović M.
Journal name J Extracell Vesicles
Publication year2022
SampleSerum
Sample nameMild COVID-19 patients
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Methods used in the studyFlow cytometry
EV-TRACK -

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