Gene description for ITGB2
Gene name	integrin subunit beta 2
Gene symbol	ITGB2
Other names/aliases	CD18 LAD LCAMB LFA-1 MAC-1 MF17 MFI7
Species	Homo sapiens
Experiment description of studies that identified ITGB2 in Macrophage
1 Experiment ID 671 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 29953960    Organism Homo sapiens Experiment description Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Authors Singhto N, Thongboonkerd V. Journal name J Proteomics Publication year 2018 Sample Macrophage Sample name U937- Human monocytic cell line differentiated to macrophages (Control) Isolation/purification methods Microfiltration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
2 Experiment ID 672 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 29953960    Organism Homo sapiens Experiment description Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Authors Singhto N, Thongboonkerd V. Journal name J Proteomics Publication year 2018 Sample Macrophage Sample name U937- Human monocytic cell line differentiated to macrophages (COM treated) Isolation/purification methods Microfiltration Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
3 Experiment ID 1016 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22711894    Organism Homo sapiens Experiment description Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Authors Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE. Journal name J Immunol. Publication year 2012 Sample Macrophage Sample name Monocyte-derived macrophages - Rab 11 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipids Methods used in the study Mass spectrometry EV-TRACK EV120137: EV-METRIC:17%, 0%