Gene description for ITGB3 |
Gene name |
integrin subunit beta 3 |
Gene symbol |
ITGB3 |
Other names/aliases |
BDPLT16 BDPLT2 BDPLT24 CD61 GP3A GPIIIa GT GT2 |
Species |
Homo sapiens |
Experiment description of studies that identified ITGB3 in Plasma |
1
|
Experiment ID | 227 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Antibody based methods
|
PubMed ID |
2942561
|
Organism | Homo sapiens |
Experiment description | Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery |
Authors | George JN, Pickett EB, Saucerman S, McEver RP, Kunicki TJ, Kieffer N, Newman PJ |
Journal name |
J Clin Invest
|
Publication year | 1986 |
Sample | Plasma |
Sample name | Plasma - Normal |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Antibody based methods |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 234 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
10648405
|
Organism | Homo sapiens |
Experiment description | Cellular origin and procoagulant properties of microparticles in meningococcal sepsis |
Authors | Nieuwland R, Berckmans RJ, McGregor S, Bö AN, Romijn FP, Westendorp RG, Hack CE, Sturk A |
Journal name |
Blood
|
Publication year | 2000 |
Sample | Plasma |
Sample name | Plasma - Meningococcal sepsis - Survived |
Isolation/purification methods | Differential centrifugation FACS |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 235 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
10648405
|
Organism | Homo sapiens |
Experiment description | Cellular origin and procoagulant properties of microparticles in meningococcal sepsis |
Authors | Nieuwland R, Berckmans RJ, McGregor S, Bö AN, Romijn FP, Westendorp RG, Hack CE, Sturk A |
Journal name |
Blood
|
Publication year | 2000 |
Sample | Plasma |
Sample name | Plasma - Normal |
Isolation/purification methods | Differential centrifugation FACS |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 236 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
10648405
|
Organism | Homo sapiens |
Experiment description | Cellular origin and procoagulant properties of microparticles in meningococcal sepsis |
Authors | Nieuwland R, Berckmans RJ, McGregor S, Bö AN, Romijn FP, Westendorp RG, Hack CE, Sturk A |
Journal name |
Blood
|
Publication year | 2000 |
Sample | Plasma |
Sample name | Plasma - Meningococcal sepsis - Nonsurvived |
Isolation/purification methods | Differential centrifugation FACS |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 250 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
9396452
|
Organism | Homo sapiens |
Experiment description | Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant |
Authors | Nieuwland R, Berckmans RJ, Rotteveel-Eijkman RC, Maquelin KN, Roozendaal KJ, Jansen PG, ten Have K, Eijsman L, Hack CE, Sturk A |
Journal name |
Circulation
|
Publication year | 1997 |
Sample | Plasma |
Sample name | Plasma - Systemic blood - Cardiopulmonary bypass patients |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein Lipids |
Methods used in the study | FACS Annexin V-FITC |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 251 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
9396452
|
Organism | Homo sapiens |
Experiment description | Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant |
Authors | Nieuwland R, Berckmans RJ, Rotteveel-Eijkman RC, Maquelin KN, Roozendaal KJ, Jansen PG, ten Have K, Eijsman L, Hack CE, Sturk A |
Journal name |
Circulation
|
Publication year | 1997 |
Sample | Plasma |
Sample name | Plasma - Pericardial blood - Cardiopulmonary bypass patients |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein Lipids |
Methods used in the study | FACS Annexin V-FITC |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 286 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
12417540
|
Organism | Homo sapiens |
Experiment description | Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus |
Authors | Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK |
Journal name |
Circulation
|
Publication year | 2002 |
Sample | Plasma |
Sample name | Plasma - Type 2 diabetes |
Isolation/purification methods | Differential centrifugation FACS |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 287 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
12417540
|
Organism | Homo sapiens |
Experiment description | Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus |
Authors | Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK |
Journal name |
Circulation
|
Publication year | 2002 |
Sample | Plasma |
Sample name | Plasma - Normal |
Isolation/purification methods | Differential centrifugation FACS |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 354 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry [Orbitrap Velos]
|
PubMed ID |
24115447
|
Organism | Homo sapiens |
Experiment description | Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma |
Authors | Mathivanan,S. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Plasma |
Sample name | Plasma - Normal |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [Orbitrap Velos] Western blotting |
EV-TRACK |
EV130073: EV-METRIC:0%, 11%, 33%, 33%, 56%
|
|
|
10
|
Experiment ID | 418 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21049385
|
Organism | Homo sapiens |
Experiment description | The plasma microparticle proteome. |
Authors | Little KM1, Smalley DM, Harthun NL, Ley K. |
Journal name |
Semin Thromb Hemost
|
Publication year | 2010 |
Sample | Plasma |
Sample name | Normal donors-Plasma |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 443 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22329422
|
Organism | Homo sapiens |
Experiment description | Quantitative proteome profiling of normal human circulating microparticles. |
Authors | Østergaard O, Nielsen CT, Iversen LV, Jacobsen S, Tanassi JT, Heegaard NH. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Normal-Platelet-poor plasma |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 454 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22669077
|
Organism | Homo sapiens |
Experiment description | The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. |
Authors | Bosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM. |
Journal name |
J Proteomics
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Normal-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 473 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23056467
|
Organism | Homo sapiens |
Experiment description | Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. |
Authors | Al Kaabi A, Traupe T, Stutz M, Buchs N, Heller M. |
Journal name |
PLoS One
|
Publication year | 2012 |
Sample | Plasma |
Sample name | Patients of external counterpulsation therapy-Blood |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 863 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22046311
|
Organism | Mus musculus |
Experiment description | Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections |
Authors | Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA. |
Journal name |
PLoS One
|
Publication year | 2011 |
Sample | Plasma |
Sample name | Peripheral blood plasma - P. yoelii 17X infected |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS Mass spectrometry |
EV-TRACK |
EV110102: EV-METRIC:25%, 25%
|
|
|
15
|
Experiment ID | 2329 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
32487994
|
Organism | Homo sapiens |
Experiment description | Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence |
Authors | Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Plasma |
Sample name | Healthy donors |
Isolation/purification methods | Centrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
16
|
Experiment ID | 2330 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
32487994
|
Organism | Homo sapiens |
Experiment description | Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence |
Authors | Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Plasma |
Sample name | Plasmodium vivax (Malaria) patients |
Isolation/purification methods | Centrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
17
|
Experiment ID | 2433 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29320704
|
Organism | Homo sapiens |
Experiment description | Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise |
Authors | Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. |
Journal name |
Cell Metab
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Plasma |
Isolation/purification methods | Centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 2434 |
Identified molecule | Protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29320704
|
Organism | Homo sapiens |
Experiment description | Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise |
Authors | Whitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA. |
Journal name |
Cell Metab
|
Publication year | 2018 |
Sample | Plasma |
Sample name | Plasma |
Isolation/purification methods | Centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
19
|
Experiment ID | 2848 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | NWL-001 - Lung cancer patient |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
20
|
Experiment ID | 2851 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35058437
|
Organism | Homo sapiens |
Experiment description | Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 |
Authors | El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Plasma |
Sample name | CSB-024 - COVID-19 patient - convalescent phase |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|